Basic information
Locus name	AT5G57610
Organism	Arabidopsis thaliana
Taxonomic identifier	[NCBI]
Function category	Protein degradation/modification:protein kinase and phosphatases
Effect for Senescence	unclear
Gene Description	protein kinase family protein similar to protein kinase [Glycine max] GI:170047, MAP3K delta-1 protein kinase [Arabidopsis thaliana] GI:2253010; contains Pfam profile: PF00069 Eukaryotic protein kinase domain
Evidence	Genomic evidence:microarray data [Ref 1]
References	1: Buchanan-Wollaston V, Page T, Harrison E, Breeze E, Lim PO, Nam HG, Lin JF, Wu SH, Swidzinski J, Ishizaki K, Leaver CJ Comparative transcriptome analysis reveals significant differences in gene expression and signalling pathways between developmental and dark/starvation-induced senescence in Arabidopsis. Plant J. 2005 May;42(4):567-85
Gene Ontology	biological process protein phosphorylation molecular function protein kinase activity
Sequence	AT5G57610.1 | Genomic | mRNA | CDS | Protein
Microarray
Sampling	Buchanan-Wollaston V, Page T, Harrison E, Breeze E, Lim PO, Nam HG, Lin JF, Wu SH, Swidzinski J, Ishizaki K, Leaver CJ. Comparative transcriptome analysis reveals significant differences in gene expression and signalling pathways between developmental and dark/starvation-induced senescence in Arabidopsis. Plant J. 2005 May;42(4)
Comparation	Legends: Col: wild type, indicates the ratio of expression in senescing leaves/green leaves. NahG, coi1 and ein2: indicates the ratio of expression in senescing leaves of mutant/senescing wild type. D/L: ratio of DARK 5d/control. CD: Cell Death, ratio of starved cell suspension culture/control. Genes showing at least 3 fold (ratio) up regulation during leaf senescence.
miRNA Interaction
Details	target: AT5G57610.1  miRNA: ath-miR419 miRNA: ath-miR419 mfe: -24.8 kcal/mol  p-value: 0.047594  position:  2761  target 5' A  G           C U   U 3'             GA AUCCUCAGCGU C AUA              UU UAGGAGUCGUA G UAU   miRNA  3' G  G           A     U 5'
Ortholog Group
Ortholog Groups: OG5_144926	Accession Taxon NP_173077 Arabidopsis thaliana NP_178075 Arabidopsis thaliana NP_181050 Arabidopsis thaliana NP_200569 ( AT5G57610 ) Arabidopsis thaliana 122213 Chlamydomonas reinhardtii NP_001067178 Oryza sativa Japonica Group e_gw1.131.129.1 Physcomitrella patens subsp. patens estExt_fgenesh1_pm.C_660028 Physcomitrella patens subsp. patens 30169.m006307 Ricinus communis 30169.m006308 Ricinus communis 30179.m000563 Ricinus communis XP_002956794 Volvox carteri f. nagariensis
Cross Link
Database Entry ID E-value Start End InterPro ID Description SMART SM00666 1.4E-32 38 123 IPR000270 Phox/Bem1p Pfam PF00564 6.8E-20 39 124 IPR000270 Phox/Bem1p SUPERFAMILY SSF54277 4.9E-24 40 128 No hit NA PANTHER PTHR23257 1.5E-237 79 1054 No hit NA SUPERFAMILY SSF56112 1.6E-74 773 1042 IPR011009 Protein kinase-like domain ProSiteProfiles PS50011 40.1 781 1047 IPR000719 Protein kinase, catalytic domain SMART SM00220 7.4E-56 781 1048 IPR002290 Serine/threonine- / dual specificity protein kinase, catalytic domain Pfam PF07714 5.9E-62 782 1044 IPR001245 Serine-threonine/tyrosine-protein kinase catalytic domain ProSitePatterns PS00107 NA 787 818 IPR017441 Protein kinase, ATP binding site PRINTS PR00109 1.1E-15 863 876 IPR001245 Serine-threonine/tyrosine-protein kinase catalytic domain PRINTS PR00109 1.1E-15 900 918 IPR001245 Serine-threonine/tyrosine-protein kinase catalytic domain ProSitePatterns PS00108 NA 906 918 IPR008271 Serine/threonine-protein kinase, active site PRINTS PR00109 1.1E-15 971 993 IPR001245 Serine-threonine/tyrosine-protein kinase catalytic domain PRINTS PR00109 1.1E-15 1015 1037 IPR001245 Serine-threonine/tyrosine-protein kinase catalytic domain
Subcellular Localization
Localization	cytosol,nucleus
Evidence	SUBAcon
Pubmed ID	23180787