Basic information
Locus name	AT3G17000
Organism	Arabidopsis thaliana
Taxonomic identifier	[NCBI]
Function category	Protein degradation/modification
Effect for Senescence	unclear
Gene Description	ubiquitin-conjugating enzyme, putative similar to Non-Canonical UBiquitin Conjugating Enzyme 1 (NCUBE1) from [Gallus gallus] GI:7362937, [Mus musculus] GI:7363050, [Homo sapiens] GI:7362973; contains Pfam profile PF00179: Ubiquitin-conjugating enzyme
Evidence	Genomic evidence:microarray data [Ref 1]
References	1: Buchanan-Wollaston V, Page T, Harrison E, Breeze E, Lim PO, Nam HG, Lin JF, Wu SH, Swidzinski J, Ishizaki K, Leaver CJ Comparative transcriptome analysis reveals significant differences in gene expression and signalling pathways between developmental and dark/starvation-induced senescence in Arabidopsis. Plant J. 2005 May;42(4):567-85
Gene Ontology	molecular function acid-amino acid ligase activity
Sequence	AT3G17000.1 | Genomic | mRNA | CDS | Protein
Microarray
Sampling	Buchanan-Wollaston V, Page T, Harrison E, Breeze E, Lim PO, Nam HG, Lin JF, Wu SH, Swidzinski J, Ishizaki K, Leaver CJ. Comparative transcriptome analysis reveals significant differences in gene expression and signalling pathways between developmental and dark/starvation-induced senescence in Arabidopsis. Plant J. 2005 May;42(4)
Comparation	Legends: Col: wild type, indicates the ratio of expression in senescing leaves/green leaves. NahG, coi1 and ein2: indicates the ratio of expression in senescing leaves of mutant/senescing wild type. D/L: ratio of DARK 5d/control. CD: Cell Death, ratio of starved cell suspension culture/control. Genes showing at least 3 fold (ratio) up regulation during leaf senescence.
miRNA Interaction
Details	target: AT3G17000.1  miRNA: ath-miR397a miRNA: ath-miR397a mfe: -27.0 kcal/mol  p-value: 0.006590  position:  1059  target 5' A                    A 3'             GUCAAUGCUGCGUUUAA GA              UAGUUGCGACGUGAGUU CU   miRNA  3' G                 A    5'
Ortholog Group
Ortholog Groups: OG5_128898	Accession Taxon NP_566563 ( AT3G17000 ) Arabidopsis thaliana CMS321C Cyanidioschyzon merolae strain 10D 185318 Chlamydomonas reinhardtii ACO69049 Micromonas sp. RCC299 NP_001049901 Oryza sativa Japonica Group 0600010223 Ostreococcus tauri e_gw1.407.21.1 Physcomitrella patens subsp. patens 29889.m003283 Ricinus communis e_gw1.6.439.1 Thalassiosira pseudonana CCMP1335 XP_002958888 Volvox carteri f. nagariensis
Cross Link
Database Entry ID E-value Start End InterPro ID Description PANTHER PTHR24067 4.1E-80 1 288 No hit NA SUPERFAMILY SSF54495 7.0E-39 12 134 IPR016135 Ubiquitin-conjugating enzyme/RWD-like ProSiteProfiles PS50127 24.1 14 126 IPR000608 Ubiquitin-conjugating enzyme, E2 SMART SM00212 5.8E-30 14 174 No hit NA Pfam PF00179 8.7E-24 15 126 IPR000608 Ubiquitin-conjugating enzyme, E2
Subcellular Localization
Localization	cytosol,endoplasmic reticulum
Evidence	SUBAcon
Pubmed ID	23180787