Basic information
Locus name	AT1G77000
Organism	Arabidopsis thaliana
Taxonomic identifier	[NCBI]
Function category	Protein degradation/modification:F-box
Effect for Senescence	unclear
Gene Description	F-box family protein similar to GP|21554029| F-box protein AtFBL5 from [Arabidopsis thaliana]; similar to F-box protein FBL2 GI:6063090 from [Homo sapiens]
Evidence	Genomic evidence:microarray data [Ref 1]
References	1: Buchanan-Wollaston V, Page T, Harrison E, Breeze E, Lim PO, Nam HG, Lin JF, Wu SH, Swidzinski J, Ishizaki K, Leaver CJ Comparative transcriptome analysis reveals significant differences in gene expression and signalling pathways between developmental and dark/starvation-induced senescence in Arabidopsis. Plant J. 2005 May;42(4):567-85
Gene Ontology	molecular function protein binding
Sequence	AT1G77000.1 | Genomic | mRNA | CDS | Protein
Microarray
Sampling	Buchanan-Wollaston V, Page T, Harrison E, Breeze E, Lim PO, Nam HG, Lin JF, Wu SH, Swidzinski J, Ishizaki K, Leaver CJ. Comparative transcriptome analysis reveals significant differences in gene expression and signalling pathways between developmental and dark/starvation-induced senescence in Arabidopsis. Plant J. 2005 May;42(4)
Comparation	Legends: Col: wild type, indicates the ratio of expression in senescing leaves/green leaves. NahG, coi1 and ein2: indicates the ratio of expression in senescing leaves of mutant/senescing wild type. D/L: ratio of DARK 5d/control. CD: Cell Death, ratio of starved cell suspension culture/control. Genes showing at least 3 fold (ratio) up regulation during leaf senescence.
miRNA Interaction
Details	target: AT1G77000.1  miRNA: ath-miR2938 miRNA: ath-miR2938 mfe: -25.8 kcal/mol  p-value: 0.027900  position:  235  target 5' G             U       U 3'             UGGAG CUUCUCA GAAGAUU              ACCUU GGAGAGU UUUCUAG   miRNA  3' G     G                 5'
Ortholog Group
Ortholog Groups: OG5_153396	Accession Taxon NP_564139 Arabidopsis thaliana NP_565147 ( AT1G77000 ) Arabidopsis thaliana NP_001045004 Oryza sativa Japonica Group NP_001055598 Oryza sativa Japonica Group e_gw1.128.81.1 Physcomitrella patens subsp. patens e_gw1.371.8.1 Physcomitrella patens subsp. patens estExt_gwp_gw1.C_3640007 Physcomitrella patens subsp. patens 29648.m001928 Ricinus communis
Cross Link
Database Entry ID E-value Start End InterPro ID Description PANTHER PTHR23125 7.8E-248 1 355 No hit NA SUPERFAMILY SSF81383 2.8E-6 27 63 IPR001810 F-box domain, cyclin-like Pfam PF00646 7.1E-5 28 62 IPR001810 F-box domain, cyclin-like SMART SM00367 580.0 63 88 IPR006553 Leucine-rich repeat, cysteine-containing subtype SUPERFAMILY SSF52047 5.9E-38 64 321 No hit NA SMART SM00367 140.0 89 115 IPR006553 Leucine-rich repeat, cysteine-containing subtype SMART SM00367 2.5E-6 116 141 IPR006553 Leucine-rich repeat, cysteine-containing subtype Pfam PF13516 0.2 142 162 No hit NA SMART SM00367 6.5E-5 142 167 IPR006553 Leucine-rich repeat, cysteine-containing subtype SMART SM00367 0.0 168 194 IPR006553 Leucine-rich repeat, cysteine-containing subtype Pfam PF13516 4.7E-4 195 218 No hit NA SMART SM00367 5.2E-7 195 220 IPR006553 Leucine-rich repeat, cysteine-containing subtype Pfam PF13516 0.0 221 245 No hit NA SMART SM00367 1.0E-7 221 246 IPR006553 Leucine-rich repeat, cysteine-containing subtype SMART SM00367 3.2E-7 247 272 IPR006553 Leucine-rich repeat, cysteine-containing subtype SMART SM00367 0.1 291 316 IPR006553 Leucine-rich repeat, cysteine-containing subtype