Basic information
Locus name	AT5G52640
Organism	Arabidopsis thaliana
Taxonomic identifier	[NCBI]
Function category	Others:stress and detoxification
Effect for Senescence	unclear
Gene Description	heat shock protein 81-1 (HSP81-1) / heat shock protein 83 (HSP83) nearly identical to SP|P27323 Heat shock protein 81-1 (HSP81-1) (Heat shock protein 83) {Arabidopsis thaliana}; contains Pfam profiles PF02518: ATPase, histidine kinase-, DNA gyrase B-, and HSP90-like domain protein, PF00183: Hsp90 protein
Evidence	Genomic evidence:microarray data [Ref 1]
References	1: Buchanan-Wollaston V, Page T, Harrison E, Breeze E, Lim PO, Nam HG, Lin JF, Wu SH, Swidzinski J, Ishizaki K, Leaver CJ Comparative transcriptome analysis reveals significant differences in gene expression and signalling pathways between developmental and dark/starvation-induced senescence in Arabidopsis. Plant J. 2005 May;42(4):567-85
Gene Ontology	biological process protein folding response to stress molecular function ATP binding unfolded protein binding
Sequence	AT5G52640.1 | Genomic | mRNA | CDS | Protein
Microarray
Sampling	Buchanan-Wollaston V, Page T, Harrison E, Breeze E, Lim PO, Nam HG, Lin JF, Wu SH, Swidzinski J, Ishizaki K, Leaver CJ. Comparative transcriptome analysis reveals significant differences in gene expression and signalling pathways between developmental and dark/starvation-induced senescence in Arabidopsis. Plant J. 2005 May;42(4)
Comparation	Legends: Col: wild type, indicates the ratio of expression in senescing leaves/green leaves. NahG, coi1 and ein2: indicates the ratio of expression in senescing leaves of mutant/senescing wild type. D/L: ratio of DARK 5d/control. CD: Cell Death, ratio of starved cell suspension culture/control. Genes showing at least 3 fold (ratio) up regulation during leaf senescence.
miRNA Interaction
Details	target: AT5G52640.1  miRNA: ath-miR171b miRNA: ath-miR171b mfe: -29.1 kcal/mol  p-value: 0.006760  position:  399  target 5' A              A     A 3'             GUGGUAUUGGCAUG C CAA              CACUAUAACCGUGC G GUU   miRNA  3' G              C A     5'  target: AT5G52640.1  miRNA: ath-miR171c miRNA: ath-miR171c mfe: -29.1 kcal/mol  p-value: 0.006017  position:  399  target 5' A              A     A 3'             GUGGUAUUGGCAUG C CAA              CACUAUAACCGUGC G GUU   miRNA  3' G              C A     5'  target: AT5G52640.1  miRNA: ath-miR780 miRNA: ath-miR780 mfe: -23.3 kcal/mol  p-value: 0.055165  position:  2131  target 5' C                   U 3'             UGCUAGG AUUCAC AGGA              ACGGUCU UAAGUG UUCU   miRNA  3' U       A      C    U 5'
Ortholog Group
Ortholog Groups: OG5_126623	Accession Taxon NP_178487 Arabidopsis thaliana NP_187434 Arabidopsis thaliana NP_194150 Arabidopsis thaliana NP_200076 ( AT5G52640 ) Arabidopsis thaliana NP_200411 Arabidopsis thaliana NP_200412 Arabidopsis thaliana NP_200414 Arabidopsis thaliana NP_849932 Arabidopsis thaliana NP_974606 Arabidopsis thaliana CMQ224C Cyanidioschyzon merolae strain 10D 138117 Chlamydomonas reinhardtii 154398 Chlamydomonas reinhardtii 97057 Chlamydomonas reinhardtii NP_113234 Guillardia theta ACO60985 Micromonas sp. RCC299 ACO68641 Micromonas sp. RCC299 ACO69885 Micromonas sp. RCC299 NP_001058590 Oryza sativa Japonica Group NP_001062103 Oryza sativa Japonica Group NP_001062159 Oryza sativa Japonica Group NP_001063456 Oryza sativa Japonica Group NP_001063500 Oryza sativa Japonica Group NP_001063503 Oryza sativa Japonica Group NP_001063504 Oryza sativa Japonica Group NP_001066882 Oryza sativa Japonica Group e_gw1.01.00.75.1 Ostreococcus tauri estExt_gwp_GeneWisePlus.C_Chr_10.00010241 Ostreococcus tauri estExt_gwp_GeneWisePlus.C_Chr_17.00010078 Ostreococcus tauri e_gw1.258.6.1 Physcomitrella patens subsp. patens estExt_Genewise1.C_1180132 Physcomitrella patens subsp. patens estExt_Genewise1.C_1260016 Physcomitrella patens subsp. patens estExt_Genewise1.C_2200037 Physcomitrella patens subsp. patens estExt_Genewise1.C_2910052 Physcomitrella patens subsp. patens estExt_fgenesh1_pm.C_2200009 Physcomitrella patens subsp. patens estExt_gwp_gw1.C_200100 Physcomitrella patens subsp. patens estExt_gwp_gw1.C_830068 Physcomitrella patens subsp. patens fgenesh1_pg.scaffold_267000018 Physcomitrella patens subsp. patens fgenesh1_pg.scaffold_8000034 Physcomitrella patens subsp. patens 27893.m000229 Ricinus communis 29597.m000289 Ricinus communis 30138.m003888 Ricinus communis 30169.m006619 Ricinus communis 30170.m014200 Ricinus communis 30190.m011266 Ricinus communis estExt_fgenesh1_pg.C_chr_50518 Thalassiosira pseudonana CCMP1335 fgenesh1_pg.C_chr_6000440 Thalassiosira pseudonana CCMP1335 XP_002947115 Volvox carteri f. nagariensis XP_002948054 Volvox carteri f. nagariensis XP_002949693 Volvox carteri f. nagariensis
Cross Link
Database Entry ID E-value Start End InterPro ID Description Hamap MF_00505 27.3 7 671 IPR001404 Heat shock protein Hsp90 PANTHER PTHR11528 0.0 8 705 IPR001404 Heat shock protein Hsp90 PIRSF PIRSF002583 0.0 8 700 IPR001404 Heat shock protein Hsp90 PRINTS PR00775 1.1E-83 10 30 IPR020575 Heat shock protein Hsp90, N-terminal SUPERFAMILY SSF55874 1.8E-75 10 218 IPR003594 Histidine kinase-like ATPase, ATP-binding domain ProSitePatterns PS00298 NA 30 39 IPR019805 Heat shock protein Hsp90, conserved site PRINTS PR00775 1.1E-83 31 53 IPR020575 Heat shock protein Hsp90, N-terminal SMART SM00387 1.4E-10 32 187 IPR003594 Histidine kinase-like ATPase, ATP-binding domain Pfam PF02518 4.9E-11 34 184 IPR003594 Histidine kinase-like ATPase, ATP-binding domain PRINTS PR00775 1.1E-83 80 97 IPR020575 Heat shock protein Hsp90, N-terminal PRINTS PR00775 1.1E-83 98 115 IPR020575 Heat shock protein Hsp90, N-terminal PRINTS PR00775 1.1E-83 123 145 IPR020575 Heat shock protein Hsp90, N-terminal PRINTS PR00775 1.1E-83 175 192 IPR020575 Heat shock protein Hsp90, N-terminal Pfam PF00183 4.1E-265 189 705 IPR001404 Heat shock protein Hsp90 PRINTS PR00775 1.1E-83 193 211 IPR020575 Heat shock protein Hsp90, N-terminal SUPERFAMILY SSF54211 3.1E-109 269 524 IPR020568 Ribosomal protein S5 domain 2-type fold Coils Coil NA 523 550 No hit NA SUPERFAMILY SSF110942 1.8E-38 548 670 No hit NA
Subcellular Localization
Localization	cytosol
Evidence	SUBAcon
Pubmed ID	23180787