Basic information
Locus name	AT5G63490
Alias	PB1
Organism	Arabidopsis thaliana
Taxonomic identifier	[NCBI]
Function category	Signal transduction
Effect for Senescence	unclear
Gene Description	CBS domain-containing protein / octicosapeptide/Phox/Bemp1 (PB1) domain-containing protein contains Pfam profiles: PF00571 CBS domain, PF00564: PB1 domain
Evidence	Genomic evidence:microarray data [Ref 1]
References	1: Buchanan-Wollaston V, Page T, Harrison E, Breeze E, Lim PO, Nam HG, Lin JF, Wu SH, Swidzinski J, Ishizaki K, Leaver CJ Comparative transcriptome analysis reveals significant differences in gene expression and signalling pathways between developmental and dark/starvation-induced senescence in Arabidopsis. Plant J. 2005 May;42(4):567-85
Gene Ontology	molecular function protein binding
Sequence	AT5G63490.1 | Genomic | mRNA | CDS | Protein
Microarray
Sampling	Buchanan-Wollaston V, Page T, Harrison E, Breeze E, Lim PO, Nam HG, Lin JF, Wu SH, Swidzinski J, Ishizaki K, Leaver CJ. Comparative transcriptome analysis reveals significant differences in gene expression and signalling pathways between developmental and dark/starvation-induced senescence in Arabidopsis. Plant J. 2005 May;42(4)
Comparation	Legends: Col: wild type, indicates the ratio of expression in senescing leaves/green leaves. NahG, coi1 and ein2: indicates the ratio of expression in senescing leaves of mutant/senescing wild type. D/L: ratio of DARK 5d/control. CD: Cell Death, ratio of starved cell suspension culture/control. Genes showing at least 3 fold (ratio) up regulation during leaf senescence.
miRNA Interaction
Details	target: AT5G63490.1  miRNA: ath-miR858 miRNA: ath-miR858 mfe: -26.4 kcal/mol  p-value: 0.019080  position:  201  target 5' G              U      C 3'             GAGG CGAGCGGAC GUGAAA              UUCC GCUUGUCUG UGCUUU   miRNA  3'      A         U        5'
Ortholog Group
Ortholog Groups: OG5_129976	Accession Taxon NP_181191 Arabidopsis thaliana NP_190863 Arabidopsis thaliana NP_201154 ( AT5G63490 ) Arabidopsis thaliana NP_568736 Arabidopsis thaliana NP_680412 Arabidopsis thaliana ACO70298 Micromonas sp. RCC299 NP_001045238 Oryza sativa Japonica Group NP_001045471 Oryza sativa Japonica Group NP_001065859 Oryza sativa Japonica Group NP_001066263 Oryza sativa Japonica Group e_gw1.11.64.1 Physcomitrella patens subsp. patens e_gw1.119.17.1 Physcomitrella patens subsp. patens e_gw1.86.19.1 Physcomitrella patens subsp. patens e_gw1.87.23.1 Physcomitrella patens subsp. patens estExt_gwp_gw1.C_860018 Physcomitrella patens subsp. patens 29903.m000183 Ricinus communis 30147.m014487 Ricinus communis 34735.m000048 Ricinus communis e_gw1.6.156.1 Thalassiosira pseudonana CCMP1335 thaps1_ua_kg.chr_6000178 Thalassiosira pseudonana CCMP1335
Cross Link
Database Entry ID E-value Start End InterPro ID Description PANTHER PTHR11911 3.7E-270 46 522 No hit NA SUPERFAMILY SSF54631 3.5E-26 52 169 No hit NA ProSiteProfiles PS51371 11.1 59 118 IPR000644 Cystathionine beta-synthase, core Pfam PF00571 3.8E-9 62 108 IPR000644 Cystathionine beta-synthase, core SMART SM00116 9.7E-5 62 110 IPR000644 Cystathionine beta-synthase, core Pfam PF00571 1.3E-6 121 162 IPR000644 Cystathionine beta-synthase, core ProSiteProfiles PS51371 9.3 125 183 IPR000644 Cystathionine beta-synthase, core SMART SM00116 0.1 128 172 IPR000644 Cystathionine beta-synthase, core ProSiteProfiles PS51371 9.8 225 285 IPR000644 Cystathionine beta-synthase, core Pfam PF00571 1.2E-5 230 277 IPR000644 Cystathionine beta-synthase, core SMART SM00116 2.0E-4 231 278 IPR000644 Cystathionine beta-synthase, core SUPERFAMILY SSF54631 9.2E-22 231 341 No hit NA Pfam PF00571 9.3E-5 289 335 IPR000644 Cystathionine beta-synthase, core ProSiteProfiles PS51371 9.9 293 350 IPR000644 Cystathionine beta-synthase, core SMART SM00116 5.5 296 344 IPR000644 Cystathionine beta-synthase, core SUPERFAMILY SSF54277 5.1E-17 397 486 No hit NA Pfam PF00564 8.9E-17 404 488 IPR000270 Phox/Bem1p SMART SM00666 1.7E-18 404 489 IPR000270 Phox/Bem1p