Basic information
Locus name	AT3G45140
Alias	LOX2
Organism	Arabidopsis thaliana
Taxonomic identifier	[NCBI]
Function category	Hormone response pathway:JA
Effect for Senescence	promote
Gene Description	Chloroplast lipoxygenase required for wound-induced jasmonic acid accumulation in Arabidopsis.Mutants are resistant to Staphylococcus aureus and accumulate salicylic acid upon infection
Evidence	Molecular evidence:Northern [Ref 1, Ref 2]
References	1: Seltmann MA, Stingl NE, Lautenschlaeger JK, Krischke M, Mueller MJ, Berger S Differential impact of lipoxygenase 2 and jasmonates on natural and stress-induced senescence in Arabidopsis. Plant Physiol. 2010 Apr;152(4):1940-50 2: He Y, Fukushige H, Hildebrand DF, Gan S Evidence supporting a role of jasmonic acid in Arabidopsis leaf senescence. Plant Physiol. 2002 Mar;128(3):876-84
Gene Ontology	biological process oxidation-reduction process molecular function metal ion binding oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
Pathway	KEGG map00591 (EC 1.13.11.12) map00592 (EC 1.13.11.12) MetaCyc PWY-5410
Sequence	AT3G45140.1 | Genomic | mRNA | CDS | Protein
Mutant information
Mutant name	LOX2-RNAi
Mutant/Transgenic	transgenic
Ecotype	Col-0
Mutagenesis type	RNAi
Ortholog Group
Ortholog Groups: OG5_127482	Accession Taxon NP_175900 Arabidopsis thaliana NP_176923 Arabidopsis thaliana NP_177396 Arabidopsis thaliana NP_188879 Arabidopsis thaliana NP_564021 Arabidopsis thaliana NP_566875 ( AT3G45140 ) Arabidopsis thaliana 144677 Chlamydomonas reinhardtii NP_001046180 Oryza sativa Japonica Group NP_001049158 Oryza sativa Japonica Group NP_001050990 Oryza sativa Japonica Group NP_001050993 Oryza sativa Japonica Group NP_001050995 Oryza sativa Japonica Group NP_001051212 Oryza sativa Japonica Group NP_001052913 Oryza sativa Japonica Group NP_001055143 Oryza sativa Japonica Group NP_001062199 Oryza sativa Japonica Group NP_001062200 Oryza sativa Japonica Group NP_001067011 Oryza sativa Japonica Group NP_001067015 Oryza sativa Japonica Group NP_001068135 Oryza sativa Japonica Group e_gw1.171.1.1 Physcomitrella patens subsp. patens e_gw1.21.1.1 Physcomitrella patens subsp. patens e_gw1.434.22.1 Physcomitrella patens subsp. patens e_gw1.97.30.1 Physcomitrella patens subsp. patens estExt_Genewise1.C_4190013 Physcomitrella patens subsp. patens estExt_fgenesh1_pg.C_4190004 Physcomitrella patens subsp. patens estExt_gwp_gw1.C_2320058 Physcomitrella patens subsp. patens estExt_gwp_gw1.C_4190009 Physcomitrella patens subsp. patens estExt_gwp_gw1.C_4190017 Physcomitrella patens subsp. patens estExt_gwp_gw1.C_700115 Physcomitrella patens subsp. patens 29468.m000030 Ricinus communis 29680.m001710 Ricinus communis 29726.m003891 Ricinus communis 29808.m000898 Ricinus communis 29851.m002422 Ricinus communis 29851.m002424 Ricinus communis 29929.m004699 Ricinus communis 30128.m008781 Ricinus communis 30152.m002449 Ricinus communis 30169.m006387 Ricinus communis 30169.m006389 Ricinus communis 30178.m000859 Ricinus communis XP_002952279 Volvox carteri f. nagariensis XP_002952280 Volvox carteri f. nagariensis XP_002956550 Volvox carteri f. nagariensis XP_002956551 Volvox carteri f. nagariensis
Cross Link
Database Entry ID E-value Start End InterPro ID Description SUPERFAMILY SSF49723 1.9E-32 48 203 IPR008976 Lipase/lipooxygenase, PLAT/LH2 SMART SM00308 2.6E-44 73 200 IPR001024 Lipoxygenase, LH2 ProSiteProfiles PS50095 19.0 79 199 IPR001024 Lipoxygenase, LH2 PANTHER PTHR11771 0.0 85 896 IPR000907 Lipoxygenase Pfam PF01477 9.9E-11 134 198 IPR001024 Lipoxygenase, LH2 PRINTS PR00468 1.0E-69 169 187 IPR001246 Lipoxygenase, plant PRINTS PR00468 1.0E-69 195 216 IPR001246 Lipoxygenase, plant ProSiteProfiles PS51393 295.8 202 896 IPR013819 Lipoxygenase, C-terminal SUPERFAMILY SSF48484 6.8E-255 204 896 IPR013819 Lipoxygenase, C-terminal Pfam PF00305 7.3E-297 209 880 IPR013819 Lipoxygenase, C-terminal PRINTS PR00468 1.0E-69 237 253 IPR001246 Lipoxygenase, plant PRINTS PR00468 1.0E-69 269 288 IPR001246 Lipoxygenase, plant PRINTS PR00468 1.0E-69 335 356 IPR001246 Lipoxygenase, plant PRINTS PR00468 1.0E-69 379 395 IPR001246 Lipoxygenase, plant PRINTS PR00468 1.0E-69 418 437 IPR001246 Lipoxygenase, plant PRINTS PR00468 1.0E-69 486 510 IPR001246 Lipoxygenase, plant PRINTS PR00087 1.3E-19 531 548 IPR013819 Lipoxygenase, C-terminal PRINTS PR00087 1.3E-19 549 566 IPR013819 Lipoxygenase, C-terminal ProSitePatterns PS00711 NA 549 563 IPR020833 Lipoxygenase, iron binding site PRINTS PR00087 1.3E-19 569 589 IPR013819 Lipoxygenase, C-terminal ProSitePatterns PS00081 NA 576 586 IPR020834 Lipoxygenase, conserved site PRINTS PR00468 1.0E-69 809 823 IPR001246 Lipoxygenase, plant
Subcellular Localization
Localization	plastid
Evidence	SUBAcon
Pubmed ID	23180787