Basic information
Locus name	AT2G27150
Alias	AAO3
Organism	Arabidopsis thaliana
Taxonomic identifier	[NCBI]
Function category	Hormone response pathway:Auxin
Effect for Senescence	unclear
Gene Description	aldehyde oxidase 3 (AAO3) identical to GP:3172044:gnl:PID:d1029570:AB010080
Evidence	Genomic evidence:microarray data [Ref 1]
References	1: Buchanan-Wollaston V, Page T, Harrison E, Breeze E, Lim PO, Nam HG, Lin JF, Wu SH, Swidzinski J, Ishizaki K, Leaver CJ Comparative transcriptome analysis reveals significant differences in gene expression and signalling pathways between developmental and dark/starvation-induced senescence in Arabidopsis. Plant J. 2005 May;42(4):567-85
Gene Ontology	biological process oxidation-reduction process molecular function electron carrier activity iron ion binding iron-sulfur cluster binding metal ion binding oxidoreductase activity
Sequence	AT2G27150.1 | Genomic | mRNA | CDS | Protein AT2G27150.2 | Genomic | mRNA | CDS | Protein
Microarray
Sampling	Buchanan-Wollaston V, Page T, Harrison E, Breeze E, Lim PO, Nam HG, Lin JF, Wu SH, Swidzinski J, Ishizaki K, Leaver CJ. Comparative transcriptome analysis reveals significant differences in gene expression and signalling pathways between developmental and dark/starvation-induced senescence in Arabidopsis. Plant J. 2005 May;42(4)
Comparation	Legends: Col: wild type, indicates the ratio of expression in senescing leaves/green leaves. NahG, coi1 and ein2: indicates the ratio of expression in senescing leaves of mutant/senescing wild type. D/L: ratio of DARK 5d/control. CD: Cell Death, ratio of starved cell suspension culture/control. Genes showing at least 3 fold (ratio) up regulation during leaf senescence.
miRNA Interaction
Details	target: AT2G27150.1  miRNA: ath-miR828 miRNA: ath-miR828 mfe: -24.8 kcal/mol  p-value: 0.012046  position:  1985  target 5' A     C         U    C   G 3'             UGGAG AUUCAUUUA AGCA AGA              ACCUU UGAGUAAAU UCGU UCU   miRNA  3'       A                    5'  target: AT2G27150.1  miRNA: ath-miR852 miRNA: ath-miR852 mfe: -24.8 kcal/mol  p-value: 0.065379  position:  326  target 5' G       U            G 3'             AGGG UG GGUGCUUGUCUU              UCUU AU CCGCGAAUAGAA   miRNA  3' G    G  U              5'  target: AT2G27150.2  miRNA: ath-miR828 miRNA: ath-miR828 mfe: -24.8 kcal/mol  p-value: 0.014079  position:  1985  target 5' A     C         U    C   G 3'             UGGAG AUUCAUUUA AGCA AGA              ACCUU UGAGUAAAU UCGU UCU   miRNA  3'       A                    5'  target: AT2G27150.2  miRNA: ath-miR852 miRNA: ath-miR852 mfe: -24.8 kcal/mol  p-value: 0.076800  position:  326  target 5' G       U            G 3'             AGGG UG GGUGCUUGUCUU              UCUU AU CCGCGAAUAGAA   miRNA  3' G    G  U              5'
Ortholog Group
Ortholog Groups: OG5_127252	Accession Taxon NP_001077966 ( AT2G27150 ) Arabidopsis thaliana NP_180283 Arabidopsis thaliana NP_189946 Arabidopsis thaliana NP_195215 Arabidopsis thaliana NP_195216 Arabidopsis thaliana NP_563711 Arabidopsis thaliana NP_568407 Arabidopsis thaliana NP_851049 Arabidopsis thaliana 117669 Chlamydomonas reinhardtii ACO65070 Micromonas sp. RCC299 NP_001050420 Oryza sativa Japonica Group NP_001051517 Oryza sativa Japonica Group NP_001051518 Oryza sativa Japonica Group NP_001058964 Oryza sativa Japonica Group NP_001059379 Oryza sativa Japonica Group NP_001064133 Oryza sativa Japonica Group e_gw1.170.7.1 Physcomitrella patens subsp. patens estExt_fgenesh1_pg.C_440069 Physcomitrella patens subsp. patens estExt_fgenesh1_pm.C_930001 Physcomitrella patens subsp. patens 29976.m000486 Ricinus communis 30169.m006431 Ricinus communis 47744.m000020 Ricinus communis estExt_thaps1_ua_kg.C_chr_220040 Thalassiosira pseudonana CCMP1335 XP_002953715 Volvox carteri f. nagariensis
Cross Link
Database Entry ID E-value Start End InterPro ID Description PIRSF PIRSF000127 0.0 1 1329 IPR016208 Aldehyde oxidase/xanthine dehydrogenase ProSiteProfiles PS51085 9.9 1 88 IPR001041 2Fe-2S ferredoxin-type domain SUPERFAMILY SSF54292 2.2E-20 1 89 IPR001041 2Fe-2S ferredoxin-type domain PANTHER PTHR11908 0.0 3 1332 No hit NA Pfam PF00111 3.7E-8 6 73 IPR001041 2Fe-2S ferredoxin-type domain ProSitePatterns PS00197 NA 40 48 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site Pfam PF01799 8.0E-22 84 163 IPR002888 [2Fe-2S]-binding SUPERFAMILY SSF47741 6.0E-32 96 206 IPR002888 [2Fe-2S]-binding SUPERFAMILY SSF56176 1.1E-42 187 397 IPR016166 FAD-binding, type 2 ProSiteProfiles PS51387 19.5 219 400 IPR016166 FAD-binding, type 2 Pfam PF00941 2.6E-41 224 398 IPR002346 Molybdopterin dehydrogenase, FAD-binding SUPERFAMILY SSF55447 3.3E-12 409 520 IPR005107 CO dehydrogenase flavoprotein, C-terminal SMART SM01092 1.3E-6 411 520 IPR005107 CO dehydrogenase flavoprotein, C-terminal Pfam PF03450 1.1E-17 412 518 IPR005107 CO dehydrogenase flavoprotein, C-terminal SUPERFAMILY SSF54665 1.6E-35 556 689 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead Pfam PF01315 4.1E-31 579 688 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead SMART SM01008 2.6E-30 579 689 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead SUPERFAMILY SSF56003 1.4E-158 693 1317 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding Pfam PF02738 3.4E-180 700 1239 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding
Subcellular Localization
Localization	cytosol
Evidence	SUBAcon
Pubmed ID	23180787