Basic information
Locus name	At1g50030
Alias	TOR1
Organism	Arabidopsis thaliana
Taxonomic identifier	[NCBI]
Function category	Nutrient recycling
Effect for Senescence	promote
Gene Description	TARGET OF RAPAMYCIN
Evidence	Genetic evidence:Mutant [Ref 1]
References	1: Ren M, Venglat P, Qiu S, Feng L, Cao Y, Wang E, Xiang D, Wang J, Alexander D, Chalivendra S, Logan D, Mattoo A, Selvaraj G, Datla R. Target of rapamycin signaling regulates metabolism, growth, and life span in Arabidopsis. Plant Cell. 2012 Dec;24(12):4850-74. doi: 10.1105/tpc.112.107144. Epub 2012 Dec 28.
Gene Ontology	molecular function drug binding phosphotransferase activity, alcohol group as acceptor protein binding
Sequence	AT1G50030.1 | mRNA | CDS | Protein AT1G50030.2 | mRNA | CDS | Protein
Mutant information
Mutated 1 Mutant name TOR-OE1 Mutant/Transgenic transgene Ecotype Col-0 Mutagenesis type T-DNA
Mutated 2 Mutant name TOR-OE1 Mutant/Transgenic Ecotype Col-0 Mutagenesis type transgene
Ortholog Group
Ortholog Groups: OG5_127212	Accession Taxon NP_001117459 Arabidopsis thaliana NP_175425 ( At1g50030 ) Arabidopsis thaliana CMR018C Cyanidioschyzon merolae strain 10D 176480 Chlamydomonas reinhardtii ACO68161 Micromonas sp. RCC299 NP_001054988 Oryza sativa Japonica Group gw1.01.00.11.1 Ostreococcus tauri estExt_fgenesh1_pg.C_4480004 Physcomitrella patens subsp. patens 30198.m000859 Ricinus communis 30198.m000860 Ricinus communis estExt_Genewise1.C_chr_120248 Thalassiosira pseudonana CCMP1335 XP_002954630 Volvox carteri f. nagariensis
Cross Link
Database Entry ID E-value Start End InterPro ID Description PANTHER PTHR11139 0.0 106 2481 No hit NA SUPERFAMILY SSF48371 6.4E-32 119 453 IPR016024 Armadillo-type fold SUPERFAMILY SSF48371 1.2E-118 353 822 IPR016024 Armadillo-type fold Pfam PF11865 8.2E-52 776 944 IPR024585 Domain of unknown function DUF3385, target of rapamycin protein SUPERFAMILY SSF48371 1.2E-118 867 1161 IPR016024 Armadillo-type fold SUPERFAMILY SSF48371 1.2E-118 1209 1432 IPR016024 Armadillo-type fold ProSiteProfiles PS51189 65.3 1309 1887 IPR014009 PIK-related kinase Pfam PF02259 6.1E-109 1449 1813 IPR003151 PIK-related kinase, FAT Pfam PF08771 6.1E-36 1920 2023 IPR009076 Rapamycin-binding domain SUPERFAMILY SSF47212 4.5E-37 1924 2021 IPR009076 Rapamycin-binding domain SUPERFAMILY SSF56112 1.2E-96 2005 2168 IPR011009 Protein kinase-like domain Pfam PF00454 2.7E-64 2091 2339 IPR000403 Phosphatidylinositol 3-/4-kinase, catalytic domain ProSiteProfiles PS50290 62.6 2091 2481 IPR000403 Phosphatidylinositol 3-/4-kinase, catalytic domain SMART SM00146 2.1E-96 2092 2417 IPR000403 Phosphatidylinositol 3-/4-kinase, catalytic domain ProSitePatterns PS00915 NA 2095 2109 IPR018936 Phosphatidylinositol 3/4-kinase, conserved site SUPERFAMILY SSF56112 1.2E-96 2203 2354 IPR011009 Protein kinase-like domain ProSitePatterns PS00916 NA 2232 2252 IPR018936 Phosphatidylinositol 3/4-kinase, conserved site ProSiteProfiles PS51190 17.5 2449 2481 IPR003152 PIK-related kinase, FATC Pfam PF02260 5.0E-16 2450 2481 IPR003152 PIK-related kinase, FATC
Mutant Image
The TOR overexpression line (TOR-OE1) flowers and senesces earlier compared with the wild type