Basic information
Locus name	AT1G54340
Alias	IDH
Organism	Arabidopsis thaliana
Taxonomic identifier	[NCBI]
Function category	Lipid/Carbohydrate metabolism
Effect for Senescence	Unclear
Gene Description	isocitrate dehydrogenase
Evidence	Genomic evidence:microarray data [Ref 1]
References	1: Taylor L, Nunes-Nesi A, Parsley K, Leiss A, Leach G, Coates S, Wingler A, Fernie AR, Hibberd JM Cytosolic pyruvate,orthophosphate dikinase functions in nitrogen remobilization during leaf senescence and limits individual seed growth and nitrogen content. Plant J. 2010 May 1;62(4):641-52
Gene Ontology	biological process isocitrate metabolic process oxidation-reduction process molecular function isocitrate dehydrogenase (NADP+) activity oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
Pathway	KEGG map00020 (EC 1.1.1.42) map00480 (EC 1.1.1.42) map00720 (EC 1.1.1.42) MetaCyc PWY-5913
Sequence	AT1G54340.1 | Genomic | mRNA | CDS | Protein
miRNA Interaction
Details	target: AT1G54340.1  miRNA: ath-miR773 miRNA: ath-miR773 mfe: -28.4 kcal/mol  p-value: 0.005973  position:  1070  target 5' A              C     U 3'             GGGC AAAGCUGGA AGCAA              UCUG UUUCGACCU UCGUU   miRNA  3' C    U               U 5'
Ortholog Group
Ortholog Groups: OG5_127057	Accession Taxon NP_175836 ( AT1G54340 ) Arabidopsis thaliana NP_176768 Arabidopsis thaliana NP_196963 Arabidopsis thaliana CMT216C Cyanidioschyzon merolae strain 10D 196567 Chlamydomonas reinhardtii ACO63708 Micromonas sp. RCC299 NP_001042583 Oryza sativa Japonica Group NP_001043749 Oryza sativa Japonica Group NP_001053269 Oryza sativa Japonica Group NP_001056381 Oryza sativa Japonica Group 1300010306 Ostreococcus tauri estExt_Genewise1.C_2450028 Physcomitrella patens subsp. patens fgenesh1_pg.scaffold_241000011 Physcomitrella patens subsp. patens 27914.m000430 Ricinus communis 29880.m000365 Ricinus communis 29933.m001413 Ricinus communis estExt_fgenesh1_pg.C_chr_30133 Thalassiosira pseudonana CCMP1335 XP_002957593 Volvox carteri f. nagariensis
Cross Link
Database Entry ID E-value Start End InterPro ID Description PANTHER PTHR11822 0.0 1 414 IPR004790 Isocitrate dehydrogenase NADP-dependent PIRSF PIRSF000108 1.1E-285 3 412 IPR004790 Isocitrate dehydrogenase NADP-dependent SUPERFAMILY SSF53659 5.2E-152 3 408 No hit NA TIGRFAM TIGR00127 1.0E-236 5 409 IPR004790 Isocitrate dehydrogenase NADP-dependent Pfam PF00180 1.1E-87 7 401 IPR024084 Isopropylmalate dehydrogenase-like domain ProSitePatterns PS00470 NA 272 291 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site
Subcellular Localization
Localization	peroxisome
Evidence	SUBAcon
Pubmed ID	23180787