Basic information
Locus name	AT1G69490
Alias	NAP/ANAC029
Organism	Arabidopsis thaliana
Taxonomic identifier	[NCBI]
Function category	Transcription regulation:NAC
Effect for Senescence	promote
Gene Description	Encodes a member of the NAC transcription factor gene family. It is expressed in floral primordia and upregulated by AP3 and PI. Its expression is associated with leaf senescence.
Evidence	Genetic evidence:Transgene and mutant [Ref 1]; Genomic evidence:microarray data [Ref 2]
References	1: Guo Y, Gan S AtNAP, a NAC family transcription factor, has an important role in leaf senescence. Plant J. 2006 May;46(4):601-12 2: Buchanan-Wollaston V, Page T, Harrison E, Breeze E, Lim PO, Nam HG, Lin JF, Wu SH, Swidzinski J, Ishizaki K, Leaver CJ Comparative transcriptome analysis reveals significant differences in gene expression and signalling pathways between developmental and dark/starvation-induced senescence in Arabidopsis. Plant J. 2005 May;42(4):567-85
Gene Ontology	biological process regulation of transcription, DNA-dependent molecular function DNA binding
Sequence	AT1G69490.1 | Genomic | mRNA | CDS | Protein
Mutant information
Mutated 1 Mutant name atnap Mutant/Transgenic mutant Ecotype Col-0 Mutagenesis type T-DNA insertion_knock out
Mutated 2 Mutant name Inducible overexpression of AtNAP line Mutant/Transgenic transgenic Ecotype Col-0 Mutagenesis type transgene
Microarray
Sampling	Buchanan-Wollaston V, Page T, Harrison E, Breeze E, Lim PO, Nam HG, Lin JF, Wu SH, Swidzinski J, Ishizaki K, Leaver CJ. Comparative transcriptome analysis reveals significant differences in gene expression and signalling pathways between developmental and dark/starvation-induced senescence in Arabidopsis. Plant J. 2005 May;42(4)
Comparation	Legends: Col: wild type, indicates the ratio of expression in senescing leaves/green leaves. NahG, coi1 and ein2: indicates the ratio of expression in senescing leaves of mutant/senescing wild type. D/L: ratio of DARK 5d/control. CD: Cell Death, ratio of starved cell suspension culture/control. Genes showing at least 3 fold (ratio) up regulation during leaf senescence.
miRNA Interaction
Details	target: AT1G69490.1  miRNA: ath-miR781 miRNA: ath-miR781 mfe: -28.6 kcal/mol  p-value: 0.001820  position:  410  target 5' G        A            U 3'             UAGGUGUC AGAAAGCUCUAG              AUUCAUAG UCUUUUGAGAUU   miRNA  3'          G              5'
Ortholog Group
Ortholog Groups: OG5_213067	Accession Taxon NP_564966 ( AT1G69490 ) Arabidopsis thaliana 29813.m001519 Ricinus communis
Cross Link
Database Entry ID E-value Start End InterPro ID Description PANTHER PTHR31719 2.6E-113 1 249 No hit NA SUPERFAMILY SSF101941 1.6E-65 4 161 IPR003441 No apical meristem (NAM) protein Pfam PF02365 2.8E-52 9 134 IPR003441 No apical meristem (NAM) protein ProSiteProfiles PS51005 60.6 9 161 IPR003441 No apical meristem (NAM) protein
Mutant Image
atnap mutant exhibited delay senescence phenotype compared with wild type Col-0
Subcellular Localization
Localization	nucleus
Evidence	SUBAcon
Pubmed ID	23180787