Basic information
Locus name	AT4G20930
Organism	Arabidopsis thaliana
Taxonomic identifier	[NCBI]
Function category	Others
Effect for Senescence	unclear
Gene Description	3-hydroxyisobutyrate dehydrogenase, putative; FUNCTIONS IN: in 7 functions; INVOLVED IN: pentose-phosphate shunt, valine metabolic process, valine catabolic process, metabolic process; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages;
Evidence	Genomic evidence:microarray data [Ref 1]
References	1: Breeze E, Harrison E, McHattie S, Hughes L, Hickman R, Hill C, Kiddle S, Kim YS, Penfold CA, Jenkins D, Zhang C, Morris K, Jenner C, Jackson S, Thomas B, Tabrett A, Legaie R, Moore JD, Wild DL, Ott S, Rand D, Beynon J, Denby K, Mead A, Buchanan-Wollaston High-resolution temporal profiling of transcripts during Arabidopsis leaf senescence reveals a distinct chronology of processes and regulation. Plant Cell 2011 Mar;23(3):873-94
Gene Ontology	biological process oxidation-reduction process pentose-phosphate shunt valine metabolic process molecular function oxidoreductase activity phosphogluconate dehydrogenase (decarboxylating) activity
Pathway	KEGG map00280 (EC 1.1.1.31)
Sequence	AT4G20930.1 | Genomic | mRNA | CDS | Protein
Ortholog Group
Ortholog Groups: OG5_126809	Accession Taxon NP_001030765 Arabidopsis thaliana NP_194641 Arabidopsis thaliana NP_564030 Arabidopsis thaliana NP_566768 Arabidopsis thaliana NP_567617 ( AT4G20930 ) Arabidopsis thaliana CMJ086C Cyanidioschyzon merolae strain 10D 120516 Chlamydomonas reinhardtii 139269 Chlamydomonas reinhardtii 172988 Chlamydomonas reinhardtii ACO66915 Micromonas sp. RCC299 NP_001043386 Oryza sativa Japonica Group NP_001044212 Oryza sativa Japonica Group NP_001047154 Oryza sativa Japonica Group NP_001058356 Oryza sativa Japonica Group e_gw1.05.00.248.1 Ostreococcus tauri e_gw1.10.81.1 Physcomitrella patens subsp. patens e_gw1.60.71.1 Physcomitrella patens subsp. patens estExt_Genewise1.C_250231 Physcomitrella patens subsp. patens estExt_gwp_gw1.C_4270020 Physcomitrella patens subsp. patens 29706.m001350 Ricinus communis 30005.m001255 Ricinus communis 30071.m000444 Ricinus communis 30075.m001171 Ricinus communis fgenesh1_pg.C_chr_2000624 Thalassiosira pseudonana CCMP1335 fgenesh1_pm.C_chr_4000054 Thalassiosira pseudonana CCMP1335 gw1.7.287.1 Thalassiosira pseudonana CCMP1335 XP_002946110 Volvox carteri f. nagariensis XP_002952345 Volvox carteri f. nagariensis XP_002954857 Volvox carteri f. nagariensis
Cross Link
Database Entry ID E-value Start End InterPro ID Description PANTHER PTHR22981 1.7E-152 1 347 IPR015815 Hydroxy monocarboxylic acid anion dehydrogenase, HIBADH-type PIRSF PIRSF000103 1.3E-76 32 347 IPR015815 Hydroxy monocarboxylic acid anion dehydrogenase, HIBADH-type Pfam PF03446 1.5E-41 38 210 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding SUPERFAMILY SSF51735 4.2E-37 38 210 No hit NA ProSitePatterns PS00895 NA 42 55 IPR002204 3-hydroxyisobutyrate dehydrogenase-related, conserved site TIGRFAM TIGR01692 2.9E-109 42 339 IPR011548 3-hydroxyisobutyrate dehydrogenase SUPERFAMILY SSF48179 4.0E-38 212 340 IPR008927 6-phosphogluconate dehydrogenase, C-terminal-like
Subcellular Localization
Localization	mitochondrion
Evidence	SUBAcon
Pubmed ID	23180787