Basic information
Locus name	AT4G32320
Alias	APX6
Organism	Arabidopsis thaliana
Taxonomic identifier	[NCBI]
Function category	Redox regulation
Effect for Senescence	unclear
Gene Description	APX6; FUNCTIONS IN: L-ascorbate peroxidase activity, peroxidase activity, heme binding; INVOLVED IN: response to oxidative stress; LOCATED IN: cytosol; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Haem peroxidase (InterPro:IPR010255), Plant ascorbate peroxidase (InterPro:IPR002207), Haem peroxidase, plant/fungal/bacterial (InterPro:IPR002016); BEST Arabidopsis thaliana protein match is: APX2 (ASCORBATE PEROXIDASE 2); L-ascorbate peroxidase (TAIR:AT3G09640.2); Has 5766 Blast hits to 5749 proteins in 867 species: Archae - 34; Bacteria - 1578; Metazoa - 0; Fungi - 616; Plants - 2663; Viruses - 0; Other Eukaryotes - 875 (source: NCBI BLink).
Evidence	Genomic evidence:microarray data [Ref 1]
References	1: Breeze E, Harrison E, McHattie S, Hughes L, Hickman R, Hill C, Kiddle S, Kim YS, Penfold CA, Jenkins D, Zhang C, Morris K, Jenner C, Jackson S, Thomas B, Tabrett A, Legaie R, Moore JD, Wild DL, Ott S, Rand D, Beynon J, Denby K, Mead A, Buchanan-Wollaston High-resolution temporal profiling of transcripts during Arabidopsis leaf senescence reveals a distinct chronology of processes and regulation. Plant Cell 2011 Mar;23(3):873-94
Gene Ontology	biological process oxidation-reduction process response to oxidative stress molecular function heme binding peroxidase activity
Pathway	KEGG map00360 (EC 1.11.1.7) map00680 (EC 1.11.1.7) map00940 (EC 1.11.1.7) MetaCyc PWY-5461
Sequence	AT4G32320.1 | Genomic | mRNA | CDS | Protein
miRNA Interaction
Details	target: AT4G32320.1  miRNA: ath-miR5661 miRNA: ath-miR5661 mfe: -30.8 kcal/mol  p-value: 0.000994  position: 393  target 5' A                   G  3'             AGGCUGC UGGUGUGCUUC                 UCUGAUG ACUACAUGGAG      miRNA  3' G       U           A  5'
Ortholog Group
Ortholog Groups: OG5_153349	Accession Taxon NP_194958 ( AT4G32320 ) Arabidopsis thaliana 205910 Chlamydomonas reinhardtii ACO63233 Micromonas sp. RCC299 NP_001062280 Oryza sativa Japonica Group e_gw1.08.00.306.1 Ostreococcus tauri e_gw1.277.22.1 Physcomitrella patens subsp. patens 29848.m004624 Ricinus communis thaps1_ua_kg.chr_6000133 Thalassiosira pseudonana CCMP1335 XP_002952032 Volvox carteri f. nagariensis
Cross Link
Database Entry ID E-value Start End InterPro ID Description PANTHER PTHR31356 1.2E-42 27 327 No hit NA SUPERFAMILY SSF48113 4.7E-66 96 326 IPR010255 Haem peroxidase Pfam PF00141 1.6E-43 102 304 IPR002016 Haem peroxidase, plant/fungal/bacterial PRINTS PR00458 7.3E-19 114 128 IPR002016 Haem peroxidase, plant/fungal/bacterial PRINTS PR00459 2.4E-26 114 129 IPR002207 Plant ascorbate peroxidase ProSitePatterns PS00436 NA 114 125 IPR019794 Peroxidase, active site ProSiteProfiles PS50873 20.5 114 329 IPR002016 Haem peroxidase, plant/fungal/bacterial PRINTS PR00459 2.4E-26 132 142 IPR002207 Plant ascorbate peroxidase PRINTS PR00459 2.4E-26 172 190 IPR002207 Plant ascorbate peroxidase PRINTS PR00458 7.3E-19 173 190 IPR002016 Haem peroxidase, plant/fungal/bacterial PRINTS PR00458 7.3E-19 191 203 IPR002016 Haem peroxidase, plant/fungal/bacterial PRINTS PR00459 2.4E-26 191 203 IPR002207 Plant ascorbate peroxidase PRINTS PR00459 2.4E-26 212 229 IPR002207 Plant ascorbate peroxidase PRINTS PR00459 2.4E-26 230 251 IPR002207 Plant ascorbate peroxidase PRINTS PR00458 7.3E-19 236 251 IPR002016 Haem peroxidase, plant/fungal/bacterial ProSitePatterns PS00435 NA 236 246 IPR019793 Peroxidases heam-ligand binding site PRINTS PR00459 2.4E-26 300 324 IPR002207 Plant ascorbate peroxidase
Subcellular Localization
Localization	cytosol
Evidence	SUBAcon
Pubmed ID	23180787