Basic information
Locus name	AT3G60010
Alias	ASK13
Organism	Arabidopsis thaliana
Taxonomic identifier	[NCBI]
Function category	Protein degradation/modification
Effect for Senescence	unclear
Gene Description	ARABIDOPSIS SKP1-LIKE 13 (ASK13); FUNCTIONS IN: ubiquitin-protein ligase activity, protein binding; INVOLVED IN: ubiquitin-dependent protein catabolic process; LOCATED IN: endomembrane system; EXPRESSED IN: 15 plant structures; EXPRESSED DURING: M germinated pollen stage, 4 anthesis, seedling growth, petal differentiation and expansion stage; CONTAINS InterPro DOMAIN/s: E3 ubiquitin ligase, SCF complex, Skp subunit (InterPro:IPR016897), SKP1 component, dimerisation (InterPro:IPR016072), SKP1 component (InterPro:IPR001232), BTB/POZ fold (InterPro:IPR011333), SKP1 component, POZ (InterPro:IPR016073); BEST Arabidopsis thaliana protein match is: ASK11 (ARABIDOPSIS SKP1-LIKE 11); protein binding / ubiquitin-protein ligase (TAIR:AT4G34210.1); Has 1076 Blast hits to 1074 proteins in 198 species: Archae - 0; Bacteria - 0; Metazoa - 465; Fungi - 109; Plants - 362; Viruses - 11; Other Eukaryotes - 129 (source: NCBI BLink).
Evidence	Genomic evidence:microarray data [Ref 1]
References	1: Breeze E, Harrison E, McHattie S, Hughes L, Hickman R, Hill C, Kiddle S, Kim YS, Penfold CA, Jenkins D, Zhang C, Morris K, Jenner C, Jackson S, Thomas B, Tabrett A, Legaie R, Moore JD, Wild DL, Ott S, Rand D, Beynon J, Denby K, Mead A, Buchanan-Wollaston High-resolution temporal profiling of transcripts during Arabidopsis leaf senescence reveals a distinct chronology of processes and regulation. Plant Cell 2011 Mar;23(3):873-94
Gene Ontology	biological process ubiquitin-dependent protein catabolic process
Pathway	Reactome REACT_6185
Sequence	AT3G60010.1 | Genomic | mRNA | CDS | Protein
Ortholog Group
Ortholog Groups: OG5_127430	Accession Taxon NP_565123 Arabidopsis thaliana NP_567090 ( AT3G60010 ) Arabidopsis thaliana NP_567959 Arabidopsis thaliana NP_567967 Arabidopsis thaliana NP_568603 Arabidopsis thaliana CMP118C Cyanidioschyzon merolae strain 10D 128004 Chlamydomonas reinhardtii ACO65881 Micromonas sp. RCC299 NP_001058882 Oryza sativa Japonica Group NP_001061672 Oryza sativa Japonica Group NP_001062743 Oryza sativa Japonica Group NP_001062746 Oryza sativa Japonica Group NP_001062747 Oryza sativa Japonica Group NP_001063805 Oryza sativa Japonica Group fgenesh1_pg.C_Chr_20.0001000042 Ostreococcus tauri estExt_fgenesh1_pg.C_90170 Physcomitrella patens subsp. patens estExt_fgenesh1_pm.C_70040 Physcomitrella patens subsp. patens fgenesh1_pm.scaffold_49000019 Physcomitrella patens subsp. patens 28962.m000447 Ricinus communis 30170.m014264 Ricinus communis 30170.m014265 Ricinus communis 34425.m000015 Ricinus communis e_gw1.20.162.1 Thalassiosira pseudonana CCMP1335 fgenesh1_pg.C_chr_15000067 Thalassiosira pseudonana CCMP1335 XP_002947872 Volvox carteri f. nagariensis
Cross Link
Database Entry ID E-value Start End InterPro ID Description PIRSF PIRSF028729 3.9E-74 1 154 IPR016897 E3 ubiquitin ligase, SCF complex, Skp subunit PANTHER PTHR11165 3.3E-93 2 154 IPR001232 SKP1 component SMART SM00512 7.2E-51 2 104 IPR001232 SKP1 component Pfam PF03931 2.0E-23 3 62 IPR016073 SKP1 component, POZ SUPERFAMILY SSF54695 9.7E-20 3 64 IPR011333 BTB/POZ fold Pfam PF01466 2.2E-37 75 154 IPR016072 SKP1 component, dimerisation SUPERFAMILY SSF81382 3.4E-28 75 152 IPR016072 SKP1 component, dimerisation
Subcellular Localization
Localization	cytosol,golgi
Evidence	SUBAcon
Pubmed ID	23180787