Basic information
Locus name	AT4G16780
Alias	ATHB2
Organism	Arabidopsis thaliana
Taxonomic identifier	[NCBI]
Function category	Transcription regulation
Effect for Senescence	unclear
Gene Description	ARABIDOPSIS THALIANA HOMEOBOX PROTEIN 2 (ATHB-2); FUNCTIONS IN: transcription factor activity, sequence-specific DNA binding, protein homodimerization activity, DNA binding; INVOLVED IN: in 11 processes; LOCATED IN: nucleus; EXPRESSED IN: 9 plant structures; EXPRESSED DURING: 7 growth stages; CONTAINS InterPro DOMAIN/s: HD-ZIP protein, N-terminal (InterPro:IPR006712), Helix-turn-helix motif, lambda-like repressor (InterPro:IPR000047), Homeobox (InterPro:IPR001356), Homeobox, conserved site (InterPro:IPR017970), Homeodomain-like (InterPro:IPR009057), Leucine zipper, homeobox-associated (InterPro:IPR003106), Homeodomain-related (InterPro:IPR012287); BEST Arabidopsis thaliana protein match is: HAT2; DNA binding / transcription factor/ transcription repressor (TAIR:AT5G47370.1); Has 5670 Blast hits to 5588 proteins in 379 species: Archae - 0; Bacteria - 0; Metazoa - 3894; Fungi - 230; Plants - 1439; Viruses - 17; Other Eukaryotes - 90 (source: NCBI BLink).
Evidence	Genomic evidence:microarray data [Ref 1]
References	1: Breeze E, Harrison E, McHattie S, Hughes L, Hickman R, Hill C, Kiddle S, Kim YS, Penfold CA, Jenkins D, Zhang C, Morris K, Jenner C, Jackson S, Thomas B, Tabrett A, Legaie R, Moore JD, Wild DL, Ott S, Rand D, Beynon J, Denby K, Mead A, Buchanan-Wollaston High-resolution temporal profiling of transcripts during Arabidopsis leaf senescence reveals a distinct chronology of processes and regulation. Plant Cell 2011 Mar;23(3):873-94
Gene Ontology	biological process regulation of transcription, DNA-dependent cellular component nucleus molecular function DNA binding sequence-specific DNA binding transcription factor activity sequence-specific DNA binding transcription regulatory region sequence-specific DNA binding
Sequence	AT4G16780.1 | Genomic | mRNA | CDS | Protein
Ortholog Group
Ortholog Groups: OG5_188108	Accession Taxon NP_193411 ( AT4G16780 ) Arabidopsis thaliana NP_193476 Arabidopsis thaliana NP_199548 Arabidopsis thaliana
Cross Link
Database Entry ID E-value Start End InterPro ID Description Pfam PF04618 5.8E-31 1 108 IPR006712 HD-ZIP protein, N-terminal PANTHER PTHR24326 4.5E-55 69 240 No hit NA ProSiteProfiles PS50071 17.4 124 184 IPR001356 Homeodomain SMART SM00389 5.2E-16 126 188 IPR001356 Homeodomain SUPERFAMILY SSF46689 4.3E-18 126 193 IPR009057 Homeodomain-like Pfam PF00046 6.1E-17 128 182 IPR001356 Homeodomain PRINTS PR00031 1.1E-5 155 164 IPR000047 Helix-turn-helix motif ProSitePatterns PS00027 NA 159 182 IPR017970 Homeobox, conserved site PRINTS PR00031 1.1E-5 164 180 IPR000047 Helix-turn-helix motif Coils Coil NA 183 218 No hit NA Pfam PF02183 1.3E-17 184 227 IPR003106 Leucine zipper, homeobox-associated SMART SM00340 3.8E-26 184 227 IPR003106 Leucine zipper, homeobox-associated
Subcellular Localization
Localization 1 Localization nucleus Evidence Localization with GFP-fusion protein (GFP:cDNA) Pubmed ID 10737809
Localization 2 Localization nucleus Evidence Localization with GFP-ORF fusion protein (GFP:cDNA) Pubmed ID 15610358
Localization 3 Localization nucleus Evidence SUBAcon Pubmed ID 23180787