Basic information
Locus name	AT3G21220
Alias	ATMKK5
Organism	Arabidopsis thaliana
Taxonomic identifier	[NCBI]
Function category	Signal transduction
Effect for Senescence	unclear
Gene Description	ARABIDOPSIS THALIANA MITOGEN-ACTIVATED PROTEIN KINASE KINASE 5 (ATMKK5); FUNCTIONS IN: MAP kinase kinase activity, kinase activity; INVOLVED IN: stomatal complex patterning, floral organ abscission, defense response, incompatible interaction, stomatal complex development; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Protein kinase, ATP binding site (InterPro:IPR017441), Protein kinase, core (InterPro:IPR000719), Serine/threonine protein kinase (InterPro:IPR002290), Serine/threonine protein kinase-related (InterPro:IPR017442), Protein kinase-like (InterPro:IPR011009), Serine/threonine protein kinase, active site (InterPro:IPR008271); BEST Arabidopsis thaliana protein match is: ATMKK4 (ARABIDOPSIS THALIANA MITOGEN-ACTIVATED PROTEIN KINASE KINASE 4); MAP kinase kinase/ kinase (TAIR:AT1G51660.1); Has 94754 Blast hits to 93537 proteins in 3315 species: Archae - 53; Bacteria - 8454; Metazoa - 41241; Fungi - 8407; Plants - 18504; Viruses - 491; Other Eukaryotes - 17604 (source: NCBI BLink).
Evidence	Genomic evidence:microarray data [Ref 1]
References	1: Breeze E, Harrison E, McHattie S, Hughes L, Hickman R, Hill C, Kiddle S, Kim YS, Penfold CA, Jenkins D, Zhang C, Morris K, Jenner C, Jackson S, Thomas B, Tabrett A, Legaie R, Moore JD, Wild DL, Ott S, Rand D, Beynon J, Denby K, Mead A, Buchanan-Wollaston High-resolution temporal profiling of transcripts during Arabidopsis leaf senescence reveals a distinct chronology of processes and regulation. Plant Cell 2011 Mar;23(3):873-94
Gene Ontology	biological process protein phosphorylation molecular function ATP binding protein kinase activity protein serine/threonine kinase activity
Sequence	AT3G21220.1 | Genomic | mRNA | CDS | Protein
Ortholog Group
Ortholog Groups: OG5_150257	Accession Taxon NP_173271 Arabidopsis thaliana NP_175577 Arabidopsis thaliana NP_177492 Arabidopsis thaliana NP_187274 Arabidopsis thaliana NP_188759 ( AT3G21220 ) Arabidopsis thaliana NP_001048341 Oryza sativa Japonica Group NP_001057028 Oryza sativa Japonica Group estExt_Genewise1.C_160199 Physcomitrella patens subsp. patens estExt_fgenesh1_pm.C_1140016 Physcomitrella patens subsp. patens 29748.m000383 Ricinus communis
Cross Link
Database Entry ID E-value Start End InterPro ID Description PANTHER PTHR24361 3.2E-134 13 346 No hit NA SUPERFAMILY SSF56112 9.0E-79 68 344 IPR011009 Protein kinase-like domain ProSiteProfiles PS50011 46.6 70 325 IPR000719 Protein kinase, catalytic domain SMART SM00220 1.1E-86 70 325 IPR002290 Serine/threonine- / dual specificity protein kinase, catalytic domain Pfam PF00069 2.2E-66 71 325 IPR000719 Protein kinase, catalytic domain ProSitePatterns PS00107 NA 76 99 IPR017441 Protein kinase, ATP binding site ProSitePatterns PS00108 NA 183 195 IPR008271 Serine/threonine-protein kinase, active site