Basic information
Locus name	AT5G03630
Alias	ATMDAR2
Organism	Arabidopsis thaliana
Taxonomic identifier	[NCBI]
Function category	Others
Effect for Senescence	unclear
Gene Description	ATMDAR2; FUNCTIONS IN: monodehydroascorbate reductase (NADH) activity; INVOLVED IN: response to cadmium ion, response to salt stress; LOCATED IN: cytosol; EXPRESSED IN: 26 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: FAD-dependent pyridine nucleotide-disulphide oxidoreductase (InterPro:IPR013027), FAD/NAD-linked reductase, dimerisation (InterPro:IPR016156); BEST Arabidopsis thaliana protein match is: MDHAR (MONODEHYDROASCORBATE REDUCTASE); monodehydroascorbate reductase (NADH) (TAIR:AT3G09940.1); Has 15548 Blast hits to 15528 proteins in 1711 species: Archae - 317; Bacteria - 10742; Metazoa - 673; Fungi - 378; Plants - 332; Viruses - 0; Other Eukaryotes - 3106 (source: NCBI BLink).
Evidence	Genomic evidence:microarray data [Ref 1]
References	1: Breeze E, Harrison E, McHattie S, Hughes L, Hickman R, Hill C, Kiddle S, Kim YS, Penfold CA, Jenkins D, Zhang C, Morris K, Jenner C, Jackson S, Thomas B, Tabrett A, Legaie R, Moore JD, Wild DL, Ott S, Rand D, Beynon J, Denby K, Mead A, Buchanan-Wollaston High-resolution temporal profiling of transcripts during Arabidopsis leaf senescence reveals a distinct chronology of processes and regulation. Plant Cell 2011 Mar;23(3):873-94
Gene Ontology	biological process oxidation-reduction process
Sequence	AT5G03630.1 | Genomic | mRNA | CDS | Protein
miRNA Interaction
Details	target: AT5G03630.1  miRNA: ath-miR856 miRNA: ath-miR856 mfe: -30.8 kcal/mol  p-value: 0.000104  position: 565  target 5' G    U            C     C  3'             GCUG GGUUGUUGGUGG GGUUA                 CGAC UCAAUAACCAUC CUAAU      miRNA  3'      U                     5'
Ortholog Group
Ortholog Groups: OG5_126784	Accession Taxon NP_001118607 Arabidopsis thaliana NP_001154674 Arabidopsis thaliana NP_189420 Arabidopsis thaliana NP_190856 Arabidopsis thaliana NP_564818 Arabidopsis thaliana NP_566361 Arabidopsis thaliana NP_568125 ( AT5G03630 ) Arabidopsis thaliana NP_849839 Arabidopsis thaliana NP_849840 Arabidopsis thaliana NP_849841 Arabidopsis thaliana CMT414C Cyanidioschyzon merolae strain 10D 134305 Chlamydomonas reinhardtii 139735 Chlamydomonas reinhardtii ACO65430 Micromonas sp. RCC299 NP_001047874 Oryza sativa Japonica Group NP_001047875 Oryza sativa Japonica Group NP_001061002 Oryza sativa Japonica Group NP_001062486 Oryza sativa Japonica Group NP_001063960 Oryza sativa Japonica Group estExt_fgenesh1_pm.C_Chr_05.00010013 Ostreococcus tauri estExt_Genewise1.C_900017 Physcomitrella patens subsp. patens estExt_fgenesh1_pg.C_2110037 Physcomitrella patens subsp. patens estExt_gwp_gw1.C_2370040 Physcomitrella patens subsp. patens estExt_gwp_gw1.C_2690062 Physcomitrella patens subsp. patens 27461.m000101 Ricinus communis 29917.m001987 Ricinus communis 30190.m011270 Ricinus communis estExt_Genewise1.C_chr_20089 Thalassiosira pseudonana CCMP1335 fgenesh1_pg.C_chr_8000365 Thalassiosira pseudonana CCMP1335 XP_002945853 Volvox carteri f. nagariensis XP_002948928 Volvox carteri f. nagariensis
Cross Link
Database Entry ID E-value Start End InterPro ID Description SUPERFAMILY SSF51905 4.2E-37 2 330 No hit NA PANTHER PTHR22912 8.5E-228 3 404 No hit NA Pfam PF07992 7.2E-24 8 303 IPR023753 Pyridine nucleotide-disulphide oxidoreductase, FAD/NAD(P)-binding domain PRINTS PR00411 8.3E-16 8 30 No hit NA PRINTS PR00368 2.4E-21 10 29 IPR013027 FAD-dependent pyridine nucleotide-disulphide oxidoreductase PRINTS PR00368 2.4E-21 116 134 IPR013027 FAD-dependent pyridine nucleotide-disulphide oxidoreductase Pfam PF00070 1.4E-16 166 248 IPR001327 Pyridine nucleotide-disulphide oxidoreductase, NAD-binding domain PRINTS PR00368 2.4E-21 166 184 IPR013027 FAD-dependent pyridine nucleotide-disulphide oxidoreductase PRINTS PR00411 8.3E-16 166 191 No hit NA PRINTS PR00368 2.4E-21 253 269 IPR013027 FAD-dependent pyridine nucleotide-disulphide oxidoreductase PRINTS PR00411 8.3E-16 254 268 No hit NA PRINTS PR00368 2.4E-21 278 300 IPR013027 FAD-dependent pyridine nucleotide-disulphide oxidoreductase PRINTS PR00411 8.3E-16 293 300 No hit NA SUPERFAMILY SSF55424 7.3E-13 340 431 IPR016156 FAD/NAD-linked reductase, dimerisation
Subcellular Localization
Localization	cytosol
Evidence	SUBAcon
Pubmed ID	23180787