Basic information
Locus name	AT5G26240
Alias	CLC-D
Organism	Arabidopsis thaliana
Taxonomic identifier	[NCBI]
Function category	Others
Effect for Senescence	unclear
Gene Description	CHLORIDE CHANNEL D (CLC-D); FUNCTIONS IN: anion channel activity, voltage-gated chloride channel activity; INVOLVED IN: cellular anion homeostasis, response to metal ion, unidimensional cell growth; LOCATED IN: trans-Golgi network, intracellular; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Chloride channel, core (InterPro:IPR014743), Chloride channel, voltage gated (InterPro:IPR001807), Chloride channel plant CLC (InterPro:IPR002251), Cystathionine beta-synthase, core (InterPro:IPR000644); BEST Arabidopsis thaliana protein match is: CLC-C (CHLORIDE CHANNEL C); anion channel/ voltage-gated chloride channel (TAIR:AT5G49890.1); Has 5031 Blast hits to 4226 proteins in 976 species: Archae - 92; Bacteria - 2887; Metazoa - 948; Fungi - 219; Plants - 192; Viruses - 0; Other Eukaryotes - 693 (source: NCBI BLink).
Evidence	Genomic evidence:microarray data [Ref 1]
References	1: Breeze E, Harrison E, McHattie S, Hughes L, Hickman R, Hill C, Kiddle S, Kim YS, Penfold CA, Jenkins D, Zhang C, Morris K, Jenner C, Jackson S, Thomas B, Tabrett A, Legaie R, Moore JD, Wild DL, Ott S, Rand D, Beynon J, Denby K, Mead A, Buchanan-Wollaston High-resolution temporal profiling of transcripts during Arabidopsis leaf senescence reveals a distinct chronology of processes and regulation. Plant Cell 2011 Mar;23(3):873-94
Gene Ontology	biological process chloride transport transmembrane transport cellular component membrane molecular function voltage-gated chloride channel activity
Sequence	AT5G26240.1 | Genomic | mRNA | CDS | Protein
Ortholog Group
Ortholog Groups: OG5_128607	Accession Taxon NP_001031990 Arabidopsis thaliana NP_189353 Arabidopsis thaliana NP_197996 ( AT5G26240 ) Arabidopsis thaliana NP_198313 Arabidopsis thaliana NP_198905 Arabidopsis thaliana NP_199800 Arabidopsis thaliana 38456 Chlamydomonas reinhardtii ACO67276 Micromonas sp. RCC299 NP_001047143 Oryza sativa Japonica Group NP_001054061 Oryza sativa Japonica Group NP_001066692 Oryza sativa Japonica Group e_gw1.09.00.41.1 Ostreococcus tauri e_gw1.331.2.1 Physcomitrella patens subsp. patens estExt_fgenesh1_pm.C_220039 Physcomitrella patens subsp. patens estExt_gwp_gw1.C_1370065 Physcomitrella patens subsp. patens 27394.m000358 Ricinus communis 29609.m000610 Ricinus communis 29844.m003366 Ricinus communis 30190.m010945 Ricinus communis thaps1_ua_kg.chr_11b000011 Thalassiosira pseudonana CCMP1335 XP_002947069 Volvox carteri f. nagariensis XP_002953983 Volvox carteri f. nagariensis
Cross Link
Database Entry ID E-value Start End InterPro ID Description PANTHER PTHR11689 0.0 7 789 No hit NA PRINTS PR01120 6.8E-19 50 58 IPR002251 Chloride channel ClC-plant SUPERFAMILY SSF81340 6.0E-104 54 381 IPR014743 Chloride channel, core Pfam PF00654 6.6E-92 131 555 IPR001807 Chloride channel, voltage gated PRINTS PR00762 2.8E-61 144 161 IPR001807 Chloride channel, voltage gated PRINTS PR00762 2.8E-61 175 194 IPR001807 Chloride channel, voltage gated PRINTS PR00762 2.8E-61 239 258 IPR001807 Chloride channel, voltage gated PRINTS PR01120 6.8E-19 260 268 IPR002251 Chloride channel ClC-plant PRINTS PR01120 6.8E-19 274 284 IPR002251 Chloride channel ClC-plant PRINTS PR01120 6.8E-19 292 299 IPR002251 Chloride channel ClC-plant PRINTS PR01120 6.8E-19 422 438 IPR002251 Chloride channel ClC-plant SUPERFAMILY SSF81340 6.0E-104 427 576 IPR014743 Chloride channel, core PRINTS PR00762 2.8E-61 470 490 IPR001807 Chloride channel, voltage gated PRINTS PR00762 2.8E-61 505 521 IPR001807 Chloride channel, voltage gated PRINTS PR00762 2.8E-61 523 542 IPR001807 Chloride channel, voltage gated PRINTS PR00762 2.8E-61 561 575 IPR001807 Chloride channel, voltage gated SUPERFAMILY SSF54631 1.9E-26 579 751 No hit NA Pfam PF00571 2.4E-6 589 646 IPR000644 Cystathionine beta-synthase, core ProSiteProfiles PS51371 8.5 592 652 IPR000644 Cystathionine beta-synthase, core SMART SM00116 0.1 595 647 IPR000644 Cystathionine beta-synthase, core Pfam PF00571 3.5E-7 704 751 IPR000644 Cystathionine beta-synthase, core ProSiteProfiles PS51371 11.7 704 761 IPR000644 Cystathionine beta-synthase, core SMART SM00116 4.4E-6 707 755 IPR000644 Cystathionine beta-synthase, core
Subcellular Localization
Localization	plasma membrane
Evidence	SUBAcon
Pubmed ID	23180787