Basic information
Locus name	AT3G20290
Alias	ATEHD1
Organism	Arabidopsis thaliana
Taxonomic identifier	[NCBI]
Function category	Others
Effect for Senescence	unclear
Gene Description	EPS15 HOMOLOGY DOMAIN 1 (ATEHD1); FUNCTIONS IN: GTP binding, GTPase activity, calcium ion binding; INVOLVED IN: endocytosis; LOCATED IN: endosome, microsome, membrane, cytoplasm; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: EF-HAND 2 (InterPro:IPR018249), EPS15 homology (EH) (InterPro:IPR000261), Dynamin, GTPase region (InterPro:IPR001401), EF-Hand type (InterPro:IPR011992), Calcium-binding EF-hand (InterPro:IPR002048), EF hand (InterPro:IPR018248); BEST Arabidopsis thaliana protein match is: ATEHD2 (EPS15 HOMOLOGY DOMAIN 2); GTP binding / GTPase/ calcium ion binding (TAIR:AT4G05520.1); Has 2133 Blast hits to 1415 proteins in 190 species: Archae - 0; Bacteria - 44; Metazoa - 1401; Fungi - 361; Plants - 110; Viruses - 0; Other Eukaryotes - 217 (source: NCBI BLink).
Evidence	Genomic evidence:microarray data [Ref 1]
References	1: Breeze E, Harrison E, McHattie S, Hughes L, Hickman R, Hill C, Kiddle S, Kim YS, Penfold CA, Jenkins D, Zhang C, Morris K, Jenner C, Jackson S, Thomas B, Tabrett A, Legaie R, Moore JD, Wild DL, Ott S, Rand D, Beynon J, Denby K, Mead A, Buchanan-Wollaston High-resolution temporal profiling of transcripts during Arabidopsis leaf senescence reveals a distinct chronology of processes and regulation. Plant Cell 2011 Mar;23(3):873-94
Gene Ontology	molecular function GTP binding GTPase activity calcium ion binding protein binding
Sequence	AT3G20290.1 | Genomic | mRNA | CDS | Protein AT3G20290.2 | Genomic | mRNA | CDS | Protein
Ortholog Group
Ortholog Groups: OG5_127350	Accession Taxon NP_001030731 Arabidopsis thaliana NP_566657 ( AT3G20290 ) Arabidopsis thaliana NP_567299 Arabidopsis thaliana NP_974517 Arabidopsis thaliana 205562 Chlamydomonas reinhardtii ACO61231 Micromonas sp. RCC299 NP_001045954 Oryza sativa Japonica Group NP_001054202 Oryza sativa Japonica Group NP_001058410 Oryza sativa Japonica Group e_gw1.403.8.1 Physcomitrella patens subsp. patens estExt_fgenesh1_pg.C_1520070 Physcomitrella patens subsp. patens 29640.m000405 Ricinus communis 29842.m003519 Ricinus communis e_gw1.4.190.1 Thalassiosira pseudonana CCMP1335 estExt_fgenesh1_pg.C_chr_130354 Thalassiosira pseudonana CCMP1335 XP_002946165 Volvox carteri f. nagariensis
Cross Link
Database Entry ID E-value Start End InterPro ID Description PANTHER PTHR11216 0.0 1 540 No hit NA SMART SM00027 3.6E-13 8 100 IPR000261 EPS15 homology (EH) SUPERFAMILY SSF47473 9.4E-22 12 97 No hit NA Pfam PF12763 1.8E-7 14 80 No hit NA ProSiteProfiles PS50222 10.0 14 49 IPR002048 EF-hand domain SMART SM00054 3.1 18 46 IPR002048 EF-hand domain ProSiteProfiles PS50222 8.7 52 83 IPR002048 EF-hand domain SMART SM00054 0.4 52 80 IPR002048 EF-hand domain SUPERFAMILY SSF52540 3.7E-31 190 467 IPR027417 P-loop containing nucleoside triphosphate hydrolase Pfam PF00350 6.9E-20 200 360 IPR001401 Dynamin, GTPase domain Coils Coil NA 468 489 No hit NA
Subcellular Localization
Localization	cytosol
Evidence	SUBAcon
Pubmed ID	23180787