Basic information
Locus name	AT5G01600
Alias	ATFER1
Organism	Arabidopsis thaliana
Taxonomic identifier	[NCBI]
Function category	ROS
Effect for Senescence	delay
Gene Description	Encodes a ferretin protein that is targeted to the chloroplast.
Evidence	Genetic evidence [Ref 1]
References	1: Murgia I, Vazzola V, Tarantino D, Cellier F, Ravet K, Briat JF, Soave C. Knock-out of ferritin AtFer1 causes earlier onset of age-dependent leaf senescence in Arabidopsis. Plant Physiol Biochem. 2007 Dec;45(12):898-907. Epub 2007 Sep 29.
Gene Ontology	biological process cellular iron ion homeostasis iron ion transport molecular function ferric iron binding oxidoreductase activity transition metal ion binding
Sequence	AT5G01600.1 | Genomic | mRNA | CDS | Protein
Mutant information
Mutant name	atfer1-2
Mutant/Transgenic	mutant
Ecotype	Col-0
Mutagenesis type	T-DNA
Microarray
Sampling	Buchanan-Wollaston V, Page T, Harrison E, Breeze E, Lim PO, Nam HG, Lin JF, Wu SH, Swidzinski J, Ishizaki K, Leaver CJ. Comparative transcriptome analysis reveals significant differences in gene expression and signalling pathways between developmental and dark/starvation-induced senescence in Arabidopsis. Plant J. 2005 May;42(4)
Comparation	Legends: Col: wild type, indicates the ratio of expression in senescing leaves/green leaves. NahG, coi1 and ein2: indicates the ratio of expression in senescing leaves of mutant/senescing wild type. D/L: ratio of DARK 5d/control. CD: Cell Death, ratio of starved cell suspension culture/control. Genes showing at least 3 fold (ratio) up regulation during leaf senescence.
miRNA Interaction
Details	target: AT5G01600.1  miRNA: ath-miR854a miRNA: ath-miR854a mfe: -32.8 kcal/mol  p-value: 0.001982  position:  377  target 5' U              A     A 3'             UCCUCUUUCUUAUC UCAUC              AGGAGGAGGGAUAG AGUAG   miRNA  3' G              G       5'  target: AT5G01600.1  miRNA: ath-miR854b miRNA: ath-miR854b mfe: -32.8 kcal/mol  p-value: 0.002879  position:  377  target 5' U              A     A 3'             UCCUCUUUCUUAUC UCAUC              AGGAGGAGGGAUAG AGUAG   miRNA  3' G              G       5'  target: AT5G01600.1  miRNA: ath-miR854c miRNA: ath-miR854c mfe: -32.8 kcal/mol  p-value: 0.002065  position:  377  target 5' U              A     A 3'             UCCUCUUUCUUAUC UCAUC              AGGAGGAGGGAUAG AGUAG   miRNA  3' G              G       5'  target: AT5G01600.1  miRNA: ath-miR854d miRNA: ath-miR854d mfe: -32.8 kcal/mol  p-value: 0.001989  position:  377  target 5' U              A     A 3'             UCCUCUUUCUUAUC UCAUC              AGGAGGAGGGAUAG AGUAG   miRNA  3' G              G       5'  target: AT5G01600.1  miRNA: ath-miR854e miRNA: ath-miR854e mfe: -32.8 kcal/mol  p-value: 0.002864  position:  377  target 5' U              A     A 3'             UCCUCUUUCUUAUC UCAUC              AGGAGGAGGGAUAG AGUAG   miRNA  3' G              G       5'
Ortholog Group
Ortholog Groups: OG5_127547	Accession Taxon NP_181559 Arabidopsis thaliana NP_187716 Arabidopsis thaliana NP_191168 Arabidopsis thaliana NP_195780 ( AT5G01600 ) Arabidopsis thaliana CMP227C Cyanidioschyzon merolae strain 10D 157947 Chlamydomonas reinhardtii ACO67672 Micromonas sp. RCC299 NP_001065540 Oryza sativa Japonica Group NP_001065936 Oryza sativa Japonica Group gw1.02.00.449.1 Ostreococcus tauri e_gw1.126.54.1 Physcomitrella patens subsp. patens estExt_fgenesh1_pg.C_590206 Physcomitrella patens subsp. patens estExt_gwp_gw1.C_510141 Physcomitrella patens subsp. patens 29729.m002277 Ricinus communis 29820.m000995 Ricinus communis XP_002951031 Volvox carteri f. nagariensis
Cross Link
Database Entry ID E-value Start End InterPro ID Description PANTHER PTHR11431 3.2E-163 6 255 IPR001519 Ferritin SUPERFAMILY SSF47240 2.2E-63 79 255 IPR009078 Ferritin-like superfamily ProSiteProfiles PS50905 42.2 88 241 IPR009040 Ferritin- like diiron domain Pfam PF00210 1.7E-40 97 240 IPR008331 Ferritin/DPS protein domain ProSitePatterns PS00204 NA 208 228 IPR014034 Ferritin, conserved site
Mutant Image
Knock-out of ferritin AtFer1 causes earlier onset of age-dependent leaf senescence in Arabidopsis
Subcellular Localization
Localization	plastid
Evidence	SUBAcon
Pubmed ID	23180787