Basic information
Locus name	AT3G25610
Organism	Arabidopsis thaliana
Taxonomic identifier	[NCBI]
Function category	Others
Effect for Senescence	unclear
Gene Description	haloacid dehalogenase-like hydrolase family protein; FUNCTIONS IN: ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism; INVOLVED IN: metabolic process, phospholipid transport, ATP biosynthetic process; LOCATED IN: plasma membrane; EXPRESSED IN: 12 plant structures; EXPRESSED DURING: 6 growth stages; CONTAINS InterPro DOMAIN/s: Haloacid dehalogenase-like hydrolase (InterPro:IPR005834), ATPase, P-type, phospholipid-translocating, flippase (InterPro:IPR006539), ATPase, P-type, ATPase-associated region (InterPro:IPR008250), ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter (InterPro:IPR001757), ATPase, P-type phosphorylation site (InterPro:IPR018303), HAD superfamily hydrolase-like, type 3 (InterPro:IPR013200); BEST Arabidopsis thaliana protein match is: ACA.l (autoinhibited Ca2+/ATPase II); ATPase, coupled to transmembrane movement of ions, phosphorylative mechanism / calmodulin binding (TAIR:AT1G13210.1); Has 8438 Blast hits to 7431 proteins in 929 species: Archae - 91; Bacteria - 2011; Metazoa - 2748; Fungi - 1347; Plants - 683; Viruses - 3; Other Eukaryotes - 1555 (source: NCBI BLink).
Evidence	Genomic evidence:microarray data [Ref 1]
References	1: Breeze E, Harrison E, McHattie S, Hughes L, Hickman R, Hill C, Kiddle S, Kim YS, Penfold CA, Jenkins D, Zhang C, Morris K, Jenner C, Jackson S, Thomas B, Tabrett A, Legaie R, Moore JD, Wild DL, Ott S, Rand D, Beynon J, Denby K, Mead A, Buchanan-Wollaston High-resolution temporal profiling of transcripts during Arabidopsis leaf senescence reveals a distinct chronology of processes and regulation. Plant Cell 2011 Mar;23(3):873-94
Gene Ontology	biological process cation transport phospholipid transport cellular component integral to membrane molecular function ATP binding cation-transporting ATPase activity magnesium ion binding phospholipid-translocating ATPase activity
Sequence	AT3G25610.1 | Genomic | mRNA | CDS | Protein
Microarray
Sampling	Buchanan-Wollaston V, Page T, Harrison E, Breeze E, Lim PO, Nam HG, Lin JF, Wu SH, Swidzinski J, Ishizaki K, Leaver CJ. Comparative transcriptome analysis reveals significant differences in gene expression and signalling pathways between developmental and dark/starvation-induced senescence in Arabidopsis. Plant J. 2005 May;42(4)
Comparation	Legends: Col: wild type, indicates the ratio of expression in senescing leaves/green leaves. NahG, coi1 and ein2: indicates the ratio of expression in senescing leaves of mutant/senescing wild type. Genes showing at least 3 fold (ratio) up regulation during leaf senescence.
Ortholog Group
Ortholog Groups: OG5_126610	Accession Taxon NP_172780 Arabidopsis thaliana NP_173193 Arabidopsis thaliana NP_173938 Arabidopsis thaliana NP_175830 Arabidopsis thaliana NP_176191 Arabidopsis thaliana NP_177038 Arabidopsis thaliana NP_177414 Arabidopsis thaliana NP_188006 Arabidopsis thaliana NP_189189 ( AT3G25610 ) Arabidopsis thaliana NP_189425 Arabidopsis thaliana NP_568146 Arabidopsis thaliana CMR306C Cyanidioschyzon merolae strain 10D 172401 Chlamydomonas reinhardtii 190292 Chlamydomonas reinhardtii 193025 Chlamydomonas reinhardtii ACO63501 Micromonas sp. RCC299 ACO69428 Micromonas sp. RCC299 NP_001042736 Oryza sativa Japonica Group NP_001049990 Oryza sativa Japonica Group NP_001050030 Oryza sativa Japonica Group NP_001054374 Oryza sativa Japonica Group NP_001057891 Oryza sativa Japonica Group NP_001064586 Oryza sativa Japonica Group e_gw1.06.00.22.1 Ostreococcus tauri e_gw1.38.18.1 Physcomitrella patens subsp. patens e_gw1.39.241.1 Physcomitrella patens subsp. patens estExt_Genewise1.C_2100028 Physcomitrella patens subsp. patens estExt_Genewise1.C_310043 Physcomitrella patens subsp. patens estExt_fgenesh1_pg.C_870094 Physcomitrella patens subsp. patens estExt_gwp_gw1.C_1360110 Physcomitrella patens subsp. patens estExt_gwp_gw1.C_620092 Physcomitrella patens subsp. patens fgenesh1_pg.scaffold_175000024 Physcomitrella patens subsp. patens 29593.m000173 Ricinus communis 29706.m001335 Ricinus communis 29736.m002078 Ricinus communis 29852.m002012 Ricinus communis 29915.m000480 Ricinus communis 29933.m001387 Ricinus communis 30138.m003832 Ricinus communis 30174.m008744 Ricinus communis estExt_Genewise1.C_chr_10487 Thalassiosira pseudonana CCMP1335 XP_002950894 Volvox carteri f. nagariensis XP_002950896 Volvox carteri f. nagariensis XP_002954566 Volvox carteri f. nagariensis
Cross Link
Database Entry ID E-value Start End InterPro ID Description PANTHER PTHR24092 0.0 5 1168 IPR006539 Phospholipid-transporting P-type ATPase, subfamily IV SUPERFAMILY SSF81665 2.1E-56 54 143 No hit NA TIGRFAM TIGR01652 0.0 57 1148 IPR006539 Phospholipid-transporting P-type ATPase, subfamily IV Pfam PF00122 8.8E-13 114 391 IPR008250 P-type ATPase, A domain SUPERFAMILY SSF81653 2.5E-15 141 211 No hit NA SUPERFAMILY SSF81653 2.5E-15 247 286 No hit NA SUPERFAMILY SSF81665 2.1E-56 289 422 No hit NA SUPERFAMILY SSF56784 4.4E-33 423 439 IPR023214 HAD-like domain Pfam PF12710 9.8E-16 427 874 No hit NA PRINTS PR00119 6.0E-7 428 442 IPR001757 Cation-transporting P-type ATPase ProSitePatterns PS00154 NA 430 436 IPR018303 P-type ATPase, phosphorylation site SUPERFAMILY SSF81660 5.4E-24 498 662 IPR023299 P-type ATPase, cytoplasmic domain N SUPERFAMILY SSF56784 4.4E-33 639 746 IPR023214 HAD-like domain SUPERFAMILY SSF56784 4.4E-33 819 918 IPR023214 HAD-like domain TIGRFAM TIGR01494 1.8E-31 834 945 IPR001757 Cation-transporting P-type ATPase PRINTS PR00119 6.0E-7 863 882 IPR001757 Cation-transporting P-type ATPase SUPERFAMILY SSF81665 2.1E-56 912 1142 No hit NA
Subcellular Localization
Localization	plasma membrane
Evidence	SUBAcon
Pubmed ID	23180787