Basic information
Locus name	AT5G03380
Organism	Arabidopsis thaliana
Taxonomic identifier	[NCBI]
Function category	Others
Effect for Senescence	unclear
Gene Description	heavy-metal-associated domain-containing protein; FUNCTIONS IN: metal ion binding; INVOLVED IN: metal ion transport; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Heavy metal transport/detoxification protein (InterPro:IPR006121); BEST Arabidopsis thaliana protein match is: heavy-metal-associated domain-containing protein (TAIR:AT2G36950.1); Has 3445 Blast hits to 2574 proteins in 351 species: Archae - 9; Bacteria - 365; Metazoa - 931; Fungi - 228; Plants - 1424; Viruses - 0; Other Eukaryotes - 488 (source: NCBI BLink).
Evidence	Genomic evidence:microarray data [Ref 1]
References	1: Breeze E, Harrison E, McHattie S, Hughes L, Hickman R, Hill C, Kiddle S, Kim YS, Penfold CA, Jenkins D, Zhang C, Morris K, Jenner C, Jackson S, Thomas B, Tabrett A, Legaie R, Moore JD, Wild DL, Ott S, Rand D, Beynon J, Denby K, Mead A, Buchanan-Wollaston High-resolution temporal profiling of transcripts during Arabidopsis leaf senescence reveals a distinct chronology of processes and regulation. Plant Cell 2011 Mar;23(3):873-94
Gene Ontology	biological process metal ion transport molecular function metal ion binding
Sequence	AT5G03380.1 | Genomic | mRNA | CDS | Protein AT5G03380.2 | Genomic | mRNA | CDS | Protein
Ortholog Group
Ortholog Groups: OG5_170116	Accession Taxon NP_001031825 Arabidopsis thaliana NP_195958 ( AT5G03380 ) Arabidopsis thaliana NP_565855 Arabidopsis thaliana NP_001048989 Oryza sativa Japonica Group 30078.m002291 Ricinus communis
Cross Link
Database Entry ID E-value Start End InterPro ID Description PANTHER PTHR22814 3.0E-116 1 281 No hit NA SUPERFAMILY SSF55008 1.4E-11 3 53 IPR006121 Heavy metal-associated domain, HMA Pfam PF00403 2.2E-14 4 55 IPR006121 Heavy metal-associated domain, HMA ProSiteProfiles PS50846 9.9 5 53 IPR006121 Heavy metal-associated domain, HMA SUPERFAMILY SSF55008 9.8E-11 126 183 IPR006121 Heavy metal-associated domain, HMA Pfam PF00403 4.4E-11 132 190 IPR006121 Heavy metal-associated domain, HMA
Subcellular Localization
Localization	cytosol,plasma membrane
Evidence	SUBAcon
Pubmed ID	23180787