Basic information
Locus name	AT5G61380
Alias	TOC1
Organism	Arabidopsis thaliana
Taxonomic identifier	[NCBI]
Function category	Transcription regulation
Effect for Senescence	unclear
Gene Description	TIMING OF CAB EXPRESSION 1 (TOC1); FUNCTIONS IN: transcription regulator activity, two-component response regulator activity; INVOLVED IN: circumnutation, regulation of transcription, DNA-dependent, circadian rhythm; LOCATED IN: nucleus; EXPRESSED IN: 22 plant structures;
Evidence	Genomic evidence:microarray data [Ref 1]
References	1: Breeze E, Harrison E, McHattie S, Hughes L, Hickman R, Hill C, Kiddle S, Kim YS, Penfold CA, Jenkins D, Zhang C, Morris K, Jenner C, Jackson S, Thomas B, Tabrett A, Legaie R, Moore JD, Wild DL, Ott S, Rand D, Beynon J, Denby K, Mead A, Buchanan-Wollaston High-resolution temporal profiling of transcripts during Arabidopsis leaf senescence reveals a distinct chronology of processes and regulation. Plant Cell 2011 Mar;23(3):873-94
Gene Ontology	biological process phosphorelay signal transduction system regulation of transcription, DNA-dependent molecular function phosphorelay response regulator activity protein binding
Pathway	Reactome REACT_14797
Sequence	AT5G61380.1 | Genomic | mRNA | CDS | Protein
Ortholog Group
Ortholog Groups: OG5_170758	Accession Taxon NP_200946 ( AT5G61380 ) Arabidopsis thaliana NP_001047448 Oryza sativa Japonica Group estExt_fgenesh1_pm.C_Chr_13.00010031 Ostreococcus tauri 30138.m004044 Ricinus communis
Cross Link
Database Entry ID E-value Start End InterPro ID Description PANTHER PTHR26402 1.9E-25 11 142 No hit NA SUPERFAMILY SSF52172 8.7E-25 17 144 IPR011006 CheY-like superfamily SMART SM00448 8.8E-19 19 134 IPR001789 Signal transduction response regulator, receiver domain ProSiteProfiles PS50110 26.4 20 138 IPR001789 Signal transduction response regulator, receiver domain Pfam PF00072 3.6E-17 21 132 IPR001789 Signal transduction response regulator, receiver domain Pfam PF06203 5.6E-17 533 575 IPR010402 CCT domain ProSiteProfiles PS51017 15.1 533 575 IPR010402 CCT domain
Subcellular Localization
Localization 1 Localization nucleus Evidence Localization with GFP-fusion protein (GFP:cDNA) Pubmed ID 10737809
Localization 2 Localization nucleus Evidence SUBAcon Pubmed ID 23180787