Basic information
Locus name	AT4G12300
Organism	Arabidopsis thaliana
Taxonomic identifier	[NCBI]
Function category	Redox regulation:flavonoid biosynthesis
Effect for Senescence	Unclear
Gene Description	Flavonoid 3,5-hydroxylase
Evidence	Genomic evidence:microarray data [Ref 1]
References	1: Buchanan-Wollaston V, Page T, Harrison E, Breeze E, Lim PO, Nam HG, Lin JF, Wu SH, Swidzinski J, Ishizaki K, Leaver CJ Comparative transcriptome analysis reveals significant differences in gene expression and signalling pathways between developmental and dark/starvation-induced senescence in Arabidopsis. Plant J. 2005 May;42(4):567-85
Gene Ontology	biological process oxidation-reduction process molecular function electron carrier activity heme binding iron ion binding oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
Pathway	Reactome REACT_13433
Sequence	AT4G12300.1 | Genomic | mRNA | CDS | Protein
Microarray
Sampling	Buchanan-Wollaston V, Page T, Harrison E, Breeze E, Lim PO, Nam HG, Lin JF, Wu SH, Swidzinski J, Ishizaki K, Leaver CJ. Comparative transcriptome analysis reveals significant differences in gene expression and signalling pathways between developmental and dark/starvation-induced senescence in Arabidopsis. Plant J. 2005 May;42(4)
Comparation	Legends: Col: wild type, indicates the ratio of expression in senescing leaves/green leaves. NahG, coi1 and ein2: indicates the ratio of expression in senescing leaves of mutant/senescing wild type. D/L: ratio of DARK 5d/control. CD: Cell Death, ratio of starved cell suspension culture/control. Genes showing at least 3 fold (ratio) up regulation during leaf senescence.
Ortholog Group
Ortholog Groups: OG5_163864	Accession Taxon NP_192967 ( AT4G12300 ) Arabidopsis thaliana NP_192970 Arabidopsis thaliana NP_199275 Arabidopsis thaliana NP_001043985 Oryza sativa Japonica Group NP_001062431 Oryza sativa Japonica Group 30190.m011007 Ricinus communis
Cross Link
Database Entry ID E-value Start End InterPro ID Description PANTHER PTHR24298 6.6E-115 1 515 No hit NA Pfam PF00067 1.0E-105 43 496 IPR001128 Cytochrome P450 SUPERFAMILY SSF48264 1.1E-127 43 508 IPR001128 Cytochrome P450 PRINTS PR00463 2.8E-48 70 89 IPR002401 Cytochrome P450, E-class, group I PRINTS PR00463 2.8E-48 94 115 IPR002401 Cytochrome P450, E-class, group I PRINTS PR00463 2.8E-48 303 320 IPR002401 Cytochrome P450, E-class, group I PRINTS PR00385 1.5E-10 314 331 IPR001128 Cytochrome P450 PRINTS PR00463 2.8E-48 323 349 IPR002401 Cytochrome P450, E-class, group I PRINTS PR00463 2.8E-48 366 384 IPR002401 Cytochrome P450, E-class, group I PRINTS PR00385 1.5E-10 367 378 IPR001128 Cytochrome P450 PRINTS PR00463 2.8E-48 407 431 IPR002401 Cytochrome P450, E-class, group I PRINTS PR00463 2.8E-48 444 454 IPR002401 Cytochrome P450, E-class, group I PRINTS PR00385 1.5E-10 445 454 IPR001128 Cytochrome P450 ProSitePatterns PS00086 NA 447 456 IPR017972 Cytochrome P450, conserved site PRINTS PR00385 1.5E-10 454 465 IPR001128 Cytochrome P450 PRINTS PR00463 2.8E-48 454 477 IPR002401 Cytochrome P450, E-class, group I