Basic information
Locus name	AT2G41220
Organism	Arabidopsis thaliana
Taxonomic identifier	[NCBI]
Function category	Nutrient recycling:N mobilization and transport
Effect for Senescence	Unclear
Gene Description	Glutamate synthase, chloroplast (GLU2). Upregulated in senescent leaves.
Evidence	Genomic evidence:microarray data [Ref 1]
References	1: Buchanan-Wollaston V, Page T, Harrison E, Breeze E, Lim PO, Nam HG, Lin JF, Wu SH, Swidzinski J, Ishizaki K, Leaver CJ Comparative transcriptome analysis reveals significant differences in gene expression and signalling pathways between developmental and dark/starvation-induced senescence in Arabidopsis. Plant J. 2005 May;42(4):567-85
Gene Ontology	biological process glutamate biosynthetic process metabolic process oxidation-reduction process molecular function glutamate synthase activity oxidoreductase activity, acting on the CH-NH2 group of donors oxidoreductase activity
Pathway
Sequence	AT2G41220.1 | Genomic | mRNA | CDS | Protein
Microarray
Sampling	Buchanan-Wollaston V, Page T, Harrison E, Breeze E, Lim PO, Nam HG, Lin JF, Wu SH, Swidzinski J, Ishizaki K, Leaver CJ. Comparative transcriptome analysis reveals significant differences in gene expression and signalling pathways between developmental and dark/starvation-induced senescence in Arabidopsis. Plant J. 2005 May;42(4)
Comparation	Legends: Col: wild type, indicates the ratio of expression in senescing leaves/green leaves. NahG, coi1 and ein2: indicates the ratio of expression in senescing leaves of mutant/senescing wild type. D/L: ratio of DARK 5d/control. CD: Cell Death, ratio of starved cell suspension culture/control. Genes showing at least 3 fold (ratio) up regulation during leaf senescence.
miRNA Interaction
Details	target: AT2G41220.1  miRNA: ath-miR775 miRNA: ath-miR775 mfe: -25.6 kcal/mol  p-value: 0.098318  position:  4457  target 5' C    U          A U   C 3'             UGGU UUGCUGGACA C GAA              ACCG GACGAUCUGU G CUU   miRNA  3'      U          A       5'
Ortholog Group
Ortholog Groups: OG5_126892	Accession Taxon NP_181655 ( AT2G41220 ) Arabidopsis thaliana NP_200158 Arabidopsis thaliana NP_568134 Arabidopsis thaliana NP_850763 Arabidopsis thaliana CMV060C Cyanidioschyzon merolae strain 10D 140487 Chlamydomonas reinhardtii 205746 Chlamydomonas reinhardtii ACO63113 Micromonas sp. RCC299 ACO66784 Micromonas sp. RCC299 NP_001043884 Oryza sativa Japonica Group NP_001056274 Oryza sativa Japonica Group NP_001060520 Oryza sativa Japonica Group estExt_gwp_GeneWisePlus.C_Chr_14.00010129 Ostreococcus tauri e_gw1.81.14.1 Physcomitrella patens subsp. patens e_gw1.93.13.1 Physcomitrella patens subsp. patens estExt_Genewise1.C_790134 Physcomitrella patens subsp. patens estExt_gwp_gw1.C_2120032 Physcomitrella patens subsp. patens estExt_gwp_gw1.C_420185 Physcomitrella patens subsp. patens estExt_gwp_gw1.C_580076 Physcomitrella patens subsp. patens 29612.m000378 Ricinus communis 30169.m006499 Ricinus communis estExt_Genewise1.C_chr_130128 Thalassiosira pseudonana CCMP1335 estExt_thaps1_ua_kg.C_chr_170026 Thalassiosira pseudonana CCMP1335 estExt_thaps1_ua_kg.C_chr_60307 Thalassiosira pseudonana CCMP1335 XP_002948046 Volvox carteri f. nagariensis XP_002958237 Volvox carteri f. nagariensis
Cross Link
Database Entry ID E-value Start End InterPro ID Description PANTHER PTHR11938 0.0 92 1615 No hit NA Pfam PF00310 5.0E-135 108 479 IPR000583 Class II glutamine amidotransferase domain ProSiteProfiles PS51278 20.5 108 507 IPR017932 Glutamine amidotransferase type 2 domain SUPERFAMILY SSF56235 8.5E-143 108 534 No hit NA SUPERFAMILY SSF51395 3.7E-252 552 1310 No hit NA Pfam PF04898 8.8E-114 555 850 IPR006982 Glutamate synthase, central-N Pfam PF01645 1.5E-161 908 1292 IPR002932 Glutamate synthase, central-C SUPERFAMILY SSF69336 1.6E-88 1342 1604 IPR002489 Glutamate synthase, alpha subunit, C-terminal Pfam PF01493 8.3E-63 1371 1564 IPR002489 Glutamate synthase, alpha subunit, C-terminal
Subcellular Localization
Localization	plastid
Evidence	SUBAcon
Pubmed ID	23180787