Basic information
Locus name	AT2G43080
Alias	AT-P4H-1
Organism	Arabidopsis thaliana
Taxonomic identifier	[NCBI]
Function category	Redox regulation
Effect for Senescence	unclear
Gene Description	A. THALIANA P4H ISOFORM 1 (AT-P4H-1); FUNCTIONS IN: oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors, procollagen-proline 4-dioxygenase activity; INVOLVED IN: peptidyl-proline hydroxylation to 4-hydroxy-L-proline
Evidence	Genomic evidence:microarray data [Ref 1]
References	1: Breeze E, Harrison E, McHattie S, Hughes L, Hickman R, Hill C, Kiddle S, Kim YS, Penfold CA, Jenkins D, Zhang C, Morris K, Jenner C, Jackson S, Thomas B, Tabrett A, Legaie R, Moore JD, Wild DL, Ott S, Rand D, Beynon J, Denby K, Mead A, Buchanan-Wollaston High-resolution temporal profiling of transcripts during Arabidopsis leaf senescence reveals a distinct chronology of processes and regulation. Plant Cell 2011 Mar;23(3):873-94
Gene Ontology	biological process oxidation-reduction process molecular function iron ion binding oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors oxidoreductase activity
Pathway	KEGG map00260 (EC 1.14.11.-) map00402 (EC 1.14.11.-) map00904 (EC 1.14.11.-)
Sequence	AT2G43080.1 | Genomic | mRNA | CDS | Protein
Ortholog Group
Ortholog Groups: OG5_139374	Accession Taxon NP_181836 ( AT2G43080 ) Arabidopsis thaliana NP_001052511 Oryza sativa Japonica Group estExt_Genewise1.C_80094 Physcomitrella patens subsp. patens 29888.m000316 Ricinus communis
Cross Link
Database Entry ID E-value Start End InterPro ID Description PANTHER PTHR10869 8.9E-109 42 280 No hit NA SMART SM00702 7.5E-67 84 278 IPR006620 Prolyl 4-hydroxylase, alpha subunit ProSiteProfiles PS51471 11.7 162 279 IPR005123 Oxoglutarate/iron-dependent dioxygenase Pfam PF03171 8.8E-14 164 278 IPR005123 Oxoglutarate/iron-dependent dioxygenase
Subcellular Localization
Localization	plasma membrane
Evidence	SUBAcon
Pubmed ID	23180787