Basic information
Locus name	AT2G42810
Alias	PP5
Organism	Arabidopsis thaliana
Taxonomic identifier	[NCBI]
Function category	Protein degradation/modification:phosphoprotein phosphatase activity
Effect for Senescence	unclear
Gene Description	PROTEIN PHOSPHATASE 5 (PP5); FUNCTIONS IN: protein binding, protein serine/threonine phosphatase activity, phosphoprotein phosphatase activity; INVOLVED IN: response to cadmium ion, red or far red light signaling pathway, nucleocytoplasmic transport
Evidence	Genomic evidence:microarray data [Ref 1]
References	1: Breeze E, Harrison E, McHattie S, Hughes L, Hickman R, Hill C, Kiddle S, Kim YS, Penfold CA, Jenkins D, Zhang C, Morris K, Jenner C, Jackson S, Thomas B, Tabrett A, Legaie R, Moore JD, Wild DL, Ott S, Rand D, Beynon J, Denby K, Mead A, Buchanan-Wollaston High-resolution temporal profiling of transcripts during Arabidopsis leaf senescence reveals a distinct chronology of processes and regulation. Plant Cell 2011 Mar;23(3):873-94
Gene Ontology	biological process protein dephosphorylation cellular component cytoplasm molecular function hydrolase activity phosphoprotein phosphatase activity
Sequence	AT2G42810.1 | Genomic | mRNA | CDS | Protein AT2G42810.2 | Genomic | mRNA | CDS | Protein
miRNA Interaction
Details	target: AT2G42810.2  miRNA: ath-miR5021 miRNA: ath-miR5021 mfe: -30.0 kcal/mol  p-value: 0.000097  position: 1986  target 5' U                   U  3'             UUUUCUUCUUCUUCUUUUC                 AAAAGAAGAAGAAGAAGAG      miRNA  3'                     U  5'
Ortholog Group
Ortholog Groups: OG5_128254	Accession Taxon NP_001031534 ( AT2G42810 ) Arabidopsis thaliana NP_565985 Arabidopsis thaliana CMP075C Cyanidioschyzon merolae strain 10D 31082 Chlamydomonas reinhardtii ACO61201 Micromonas sp. RCC299 NP_001054892 Oryza sativa Japonica Group estExt_fgenesh1_pm.C_800025 Physcomitrella patens subsp. patens 29993.m001069 Ricinus communis e_gw1.4.408.1 Thalassiosira pseudonana CCMP1335 XP_002953345 Volvox carteri f. nagariensis
Cross Link
Database Entry ID E-value Start End InterPro ID Description PANTHER PTHR11668 2.2E-297 1 484 No hit NA PIRSF PIRSF033096 0.0 1 484 IPR011236 Serine/threonine protein phosphatase 5 SUPERFAMILY SSF48452 1.9E-34 9 138 No hit NA Pfam PF13414 1.9E-18 12 77 No hit NA ProSiteProfiles PS50005 8.5 13 46 IPR019734 Tetratricopeptide repeat ProSiteProfiles PS50293 24.7 13 114 IPR013026 Tetratricopeptide repeat-containing domain SMART SM00028 0.0 13 46 IPR019734 Tetratricopeptide repeat ProSiteProfiles PS50005 7.3 47 80 IPR019734 Tetratricopeptide repeat SMART SM00028 0.0 47 80 IPR019734 Tetratricopeptide repeat ProSiteProfiles PS50005 12.5 81 114 IPR019734 Tetratricopeptide repeat SMART SM00028 2.7E-7 81 114 IPR019734 Tetratricopeptide repeat Pfam PF00515 7.8E-9 82 114 IPR001440 Tetratricopeptide TPR-1 Pfam PF08321 1.0E-35 120 215 IPR013235 PPP domain SUPERFAMILY SSF56300 2.1E-106 172 478 No hit NA SMART SM00156 4.3E-127 190 466 IPR006186 Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase Pfam PF00149 7.2E-38 222 416 IPR004843 Metallophosphoesterase domain PRINTS PR00114 2.6E-68 222 249 IPR006186 Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase PRINTS PR00114 2.6E-68 252 279 IPR006186 Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase PRINTS PR00114 2.6E-68 285 309 IPR006186 Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase PRINTS PR00114 2.6E-68 319 345 IPR006186 Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase PRINTS PR00114 2.6E-68 349 376 IPR006186 Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase PRINTS PR00114 2.6E-68 405 425 IPR006186 Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase PRINTS PR00114 2.6E-68 427 443 IPR006186 Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase
Subcellular Localization
Localization 1 Localization ER Evidence Localization with GFP-fusion protein (GFP:cDNA) Pubmed ID 10737809
Localization 2 Localization cytosol Evidence SUBAcon Pubmed ID 23180787
Localization 3 Localization cytosol,nucleus Evidence SUBAcon Pubmed ID 23180787