Basic information
Locus name	AT2G38080
Alias	IRX12
Organism	Arabidopsis thaliana
Taxonomic identifier	[NCBI]
Function category	Others:laccase activity
Effect for Senescence	unclear
Gene Description	IRREGULAR XYLEM 12 (IRX12); FUNCTIONS IN: laccase activity; INVOLVED IN: secondary cell wall biogenesis
Evidence	Genomic evidence:microarray data [Ref 1]
References	1: Breeze E, Harrison E, McHattie S, Hughes L, Hickman R, Hill C, Kiddle S, Kim YS, Penfold CA, Jenkins D, Zhang C, Morris K, Jenner C, Jackson S, Thomas B, Tabrett A, Legaie R, Moore JD, Wild DL, Ott S, Rand D, Beynon J, Denby K, Mead A, Buchanan-Wollaston High-resolution temporal profiling of transcripts during Arabidopsis leaf senescence reveals a distinct chronology of processes and regulation. Plant Cell 2011 Mar;23(3):873-94
Gene Ontology	biological process oxidation-reduction process molecular function copper ion binding oxidoreductase activity
Sequence	AT2G38080.1 | Genomic | mRNA | CDS | Protein
miRNA Interaction
Details	target: AT2G38080.1  miRNA: ath-miR397a miRNA: ath-miR397a mfe: -39.4 kcal/mol  p-value: 0.000096  position: 749  target 5' A                    A  3'             GUCAACGCUGCACUUAAUGA                 UAGUUGCGACGUGAGUUACU      miRNA  3' G                       5'  target: AT2G38080.1  miRNA: ath-miR397b miRNA: ath-miR397b mfe: -32.8 kcal/mol  p-value: 0.000679  position: 749  target 5' A       C            A  3'             GUCAACG UGCACUUAAUGA                 UAGUUGC ACGUGAGUUACU      miRNA  3' G       U               5'
Ortholog Group
Ortholog Groups: OG5_132798	Accession Taxon NP_173252 Arabidopsis thaliana NP_180477 Arabidopsis thaliana NP_195739 Arabidopsis thaliana NP_195946 Arabidopsis thaliana NP_200699 Arabidopsis thaliana NP_200810 Arabidopsis thaliana NP_565881 ( AT2G38080 ) Arabidopsis thaliana NP_001044772 Oryza sativa Japonica Group NP_001044773 Oryza sativa Japonica Group NP_001049699 Oryza sativa Japonica Group NP_001055744 Oryza sativa Japonica Group NP_001055746 Oryza sativa Japonica Group NP_001055747 Oryza sativa Japonica Group fgenesh1_pm.scaffold_206000007 Physcomitrella patens subsp. patens 27847.m000126 Ricinus communis 29568.m000289 Ricinus communis 29568.m000290 Ricinus communis 29568.m000293 Ricinus communis 29610.m000409 Ricinus communis 29751.m001786 Ricinus communis 29751.m001905 Ricinus communis 30004.m000427 Ricinus communis 30004.m000428 Ricinus communis 30078.m002327 Ricinus communis 30130.m000268 Ricinus communis 30131.m007048 Ricinus communis
Cross Link
Database Entry ID E-value Start End InterPro ID Description PANTHER PTHR11709 0.0 5 558 No hit NA SUPERFAMILY SSF49503 4.5E-41 19 170 IPR008972 Cupredoxin TIGRFAM TIGR03389 1.7E-274 25 558 IPR017761 Laccase Pfam PF07732 1.5E-42 33 146 IPR011707 Multicopper oxidase, type 3 SUPERFAMILY SSF49503 2.7E-41 153 321 IPR008972 Cupredoxin Pfam PF00394 8.9E-42 160 307 IPR001117 Multicopper oxidase, type 1 SUPERFAMILY SSF49503 6.1E-46 348 558 IPR008972 Cupredoxin Pfam PF07731 2.6E-38 412 541 IPR011706 Multicopper oxidase, type 2 ProSitePatterns PS00079 NA 516 536 IPR002355 Multicopper oxidase, copper-binding site ProSitePatterns PS00080 NA 521 532 IPR002355 Multicopper oxidase, copper-binding site
Subcellular Localization
Localization	extracellular
Evidence	SUBAcon
Pubmed ID	23180787