Basic information
Locus name	AT2G25070
Organism	Arabidopsis thaliana
Taxonomic identifier	[NCBI]
Function category	Protein degradation/modification
Effect for Senescence	unclear
Gene Description	protein phosphatase 2C, putative / PP2C, putative; FUNCTIONS IN: protein serine/threonine phosphatase activity, catalytic activity; INVOLVED IN: protein amino acid dephosphorylation
Evidence	Genomic evidence:microarray data [Ref 1]
References	1: Breeze E, Harrison E, McHattie S, Hughes L, Hickman R, Hill C, Kiddle S, Kim YS, Penfold CA, Jenkins D, Zhang C, Morris K, Jenner C, Jackson S, Thomas B, Tabrett A, Legaie R, Moore JD, Wild DL, Ott S, Rand D, Beynon J, Denby K, Mead A, Buchanan-Wollaston High-resolution temporal profiling of transcripts during Arabidopsis leaf senescence reveals a distinct chronology of processes and regulation. Plant Cell 2011 Mar;23(3):873-94
Gene Ontology	biological process protein dephosphorylation molecular function catalytic activity protein serine/threonine phosphatase activity
Sequence	AT2G25070.1 | Genomic | mRNA | CDS | Protein
miRNA Interaction
Details	target: AT2G25070.1  miRNA: ath-miR5645a miRNA: ath-miR5645a mfe: -25.4 kcal/mol  p-value: 0.008767  position: 533  target 5' U              G   G  3'             UUAGCGGCAUGAUU AAG                 AAUUGCUGUACUGA UUU      miRNA  3' G              G   A  5'  target: AT2G25070.1  miRNA: ath-miR5645b miRNA: ath-miR5645b mfe: -25.4 kcal/mol  p-value: 0.008673  position: 533  target 5' U              G   G  3'             UUAGCGGCAUGAUU AAG                 AAUUGCUGUACUGA UUU      miRNA  3' G              G   A  5'  target: AT2G25070.1  miRNA: ath-miR5645d miRNA: ath-miR5645d mfe: -25.4 kcal/mol  p-value: 0.007158  position: 533  target 5' U              G   G  3'             UUAGCGGCAUGAUU AAG                 AAUUGCUGUACUGA UUU      miRNA  3' G              G   A  5'  target: AT2G25070.1  miRNA: ath-miR5645e miRNA: ath-miR5645e mfe: -25.4 kcal/mol  p-value: 0.008273  position: 533  target 5' U              G   G  3'             UUAGCGGCAUGAUU AAG                 AAUUGCUGUACUGA UUU      miRNA  3' G              G   A  5'  target: AT2G25070.1  miRNA: ath-miR5645f miRNA: ath-miR5645f mfe: -25.4 kcal/mol  p-value: 0.008872  position: 533  target 5' U              G   G  3'             UUAGCGGCAUGAUU AAG                 AAUUGCUGUACUGA UUU      miRNA  3' G              G   A  5'
Ortholog Group
Ortholog Groups: OG5_126741	Accession Taxon NP_180079 ( AT2G25070 ) Arabidopsis thaliana NP_194914 Arabidopsis thaliana CMK117C Cyanidioschyzon merolae strain 10D 164613 Chlamydomonas reinhardtii 192081 Chlamydomonas reinhardtii ACO67257 Micromonas sp. RCC299 NP_001046088 Oryza sativa Japonica Group NP_001058229 Oryza sativa Japonica Group NP_001063908 Oryza sativa Japonica Group e_gw1.09.00.176.1 Ostreococcus tauri e_gw1.13.314.1 Physcomitrella patens subsp. patens e_gw1.158.75.1 Physcomitrella patens subsp. patens estExt_Genewise1.C_3150016 Physcomitrella patens subsp. patens 29848.m004528 Ricinus communis e_gw1.1.514.1 Thalassiosira pseudonana CCMP1335 e_gw1.15.82.1 Thalassiosira pseudonana CCMP1335 estExt_gwp_gw1.C_chr_10694 Thalassiosira pseudonana CCMP1335 gw1.17.74.1 Thalassiosira pseudonana CCMP1335 XP_002952433 Volvox carteri f. nagariensis XP_002954391 Volvox carteri f. nagariensis
Cross Link
Database Entry ID E-value Start End InterPro ID Description PANTHER PTHR13832 5.7E-181 1 354 IPR015655 Protein phosphatase 2C SUPERFAMILY SSF81606 5.0E-84 3 109 IPR001932 Protein phosphatase 2C (PP2C)-like SMART SM00332 2.5E-109 13 327 IPR001932 Protein phosphatase 2C (PP2C)-like Pfam PF00481 1.1E-12 23 102 IPR001932 Protein phosphatase 2C (PP2C)-like SMART SM00331 0.0 28 329 IPR001932 Protein phosphatase 2C (PP2C)-like ProSitePatterns PS01032 NA 52 60 IPR000222 Protein phosphatase 2C, manganese/magnesium aspartate binding site SUPERFAMILY SSF81606 5.0E-84 154 331 IPR001932 Protein phosphatase 2C (PP2C)-like Pfam PF00481 2.5E-60 157 313 IPR001932 Protein phosphatase 2C (PP2C)-like
Subcellular Localization
Localization	cytosol
Evidence	SUBAcon
Pubmed ID	23180787