Basic information
Locus name	AT1G64950
Alias	CYP89A5
Organism	Arabidopsis thaliana
Taxonomic identifier	[NCBI]
Function category	Redox regulation
Effect for Senescence	unclear
Gene Description	CYP89A5; FUNCTIONS IN: electron carrier activity, monooxygenase activity, iron ion binding, oxygen binding, heme binding
Evidence	Genomic evidence:microarray data [Ref 1]
References	1: Breeze E, Harrison E, McHattie S, Hughes L, Hickman R, Hill C, Kiddle S, Kim YS, Penfold CA, Jenkins D, Zhang C, Morris K, Jenner C, Jackson S, Thomas B, Tabrett A, Legaie R, Moore JD, Wild DL, Ott S, Rand D, Beynon J, Denby K, Mead A, Buchanan-Wollaston High-resolution temporal profiling of transcripts during Arabidopsis leaf senescence reveals a distinct chronology of processes and regulation. Plant Cell 2011 Mar;23(3):873-94
Gene Ontology	biological process oxidation-reduction process molecular function electron carrier activity heme binding iron ion binding oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
Pathway	Reactome REACT_13433
Sequence	AT1G64950.1 | Genomic | mRNA | CDS | Protein
Microarray
Sampling	Buchanan-Wollaston V, Page T, Harrison E, Breeze E, Lim PO, Nam HG, Lin JF, Wu SH, Swidzinski J, Ishizaki K, Leaver CJ. Comparative transcriptome analysis reveals significant differences in gene expression and signalling pathways between developmental and dark/starvation-induced senescence in Arabidopsis. Plant J. 2005 May;42(4)
Comparation	Legends: Col: wild type, indicates the ratio of expression in senescing leaves/green leaves. NahG, coi1 and ein2: indicates the ratio of expression in senescing leaves of mutant/senescing wild type. D/L: ratio of DARK 5d/control. Genes showing at least 3 fold (ratio) up regulation during leaf senescence.
Ortholog Group
Ortholog Groups: OG5_134367	Accession Taxon NP_176670 Arabidopsis thaliana NP_176673 Arabidopsis thaliana NP_176674 Arabidopsis thaliana NP_176675 ( AT1G64950 ) Arabidopsis thaliana NP_178922 Arabidopsis thaliana NP_200940 Arabidopsis thaliana NP_001057534 Oryza sativa Japonica Group NP_001061003 Oryza sativa Japonica Group NP_001064139 Oryza sativa Japonica Group NP_001065050 Oryza sativa Japonica Group NP_001065051 Oryza sativa Japonica Group NP_001065053 Oryza sativa Japonica Group NP_001065056 Oryza sativa Japonica Group NP_001065058 Oryza sativa Japonica Group NP_001065059 Oryza sativa Japonica Group e_gw1.33.86.1 Physcomitrella patens subsp. patens gw1.314.46.1 Physcomitrella patens subsp. patens 30073.m002236 Ricinus communis 30148.m001475 Ricinus communis 30148.m001476 Ricinus communis 30148.m001477 Ricinus communis 30148.m001478 Ricinus communis 30148.m001481 Ricinus communis 30148.m001482 Ricinus communis 30148.m001483 Ricinus communis
Cross Link
Database Entry ID E-value Start End InterPro ID Description PANTHER PTHR24298 2.2E-69 1 507 No hit NA Pfam PF00067 2.1E-98 33 498 IPR001128 Cytochrome P450 SUPERFAMILY SSF48264 5.2E-115 33 507 IPR001128 Cytochrome P450 PRINTS PR00463 1.2E-40 63 82 IPR002401 Cytochrome P450, E-class, group I PRINTS PR00463 1.2E-40 87 108 IPR002401 Cytochrome P450, E-class, group I PRINTS PR00463 1.2E-40 181 199 IPR002401 Cytochrome P450, E-class, group I Coils Coil NA 252 273 No hit NA PRINTS PR00463 1.2E-40 301 318 IPR002401 Cytochrome P450, E-class, group I PRINTS PR00385 2.4E-11 312 329 IPR001128 Cytochrome P450 PRINTS PR00463 1.2E-40 321 347 IPR002401 Cytochrome P450, E-class, group I PRINTS PR00463 1.2E-40 365 383 IPR002401 Cytochrome P450, E-class, group I PRINTS PR00385 2.4E-11 366 377 IPR001128 Cytochrome P450 PRINTS PR00463 1.2E-40 406 430 IPR002401 Cytochrome P450, E-class, group I PRINTS PR00463 1.2E-40 443 453 IPR002401 Cytochrome P450, E-class, group I PRINTS PR00385 2.4E-11 444 453 IPR001128 Cytochrome P450 ProSitePatterns PS00086 NA 446 455 IPR017972 Cytochrome P450, conserved site PRINTS PR00385 2.4E-11 453 464 IPR001128 Cytochrome P450 PRINTS PR00463 1.2E-40 453 476 IPR002401 Cytochrome P450, E-class, group I
Subcellular Localization
Localization	endoplasmic reticulum
Evidence	SUBAcon
Pubmed ID	23180787