Leaf Senescence DataBase

Basic information

Locus name

AT1G31230

Alias

AK-HSDH I

Organism

Arabidopsis thaliana

Taxonomic identifier

[NCBI]

Function category

Protein degradation/modification

Effect for Senescence

unclear

Gene Description

ASPARTATE KINASE-HOMOSERINE DEHYDROGENASE I (AK-HSDH I); FUNCTIONS IN: homoserine dehydrogenase activity, aspartate kinase activity; INVOLVED IN: aspartate family amino acid biosynthetic process

Evidence

Genomic evidence:microarray data [Ref 1]

References

1: Breeze E, Harrison E, McHattie S, Hughes L, Hickman R, Hill C, Kiddle S, Kim YS, Penfold CA, Jenkins D, Zhang C, Morris K, Jenner C, Jackson S, Thomas B, Tabrett A, Legaie R, Moore JD, Wild DL, Ott S, Rand D, Beynon J, Denby K, Mead A, Buchanan-Wollaston
High-resolution temporal profiling of transcripts during Arabidopsis leaf senescence reveals a distinct chronology of processes and regulation.
Plant Cell 2011 Mar;23(3):873-94

Gene Ontology

biological process	aspartate family amino acid biosynthetic process cellular amino acid biosynthetic process cellular amino acid metabolic process metabolic process oxidation-reduction process
molecular function	amino acid binding aspartate kinase activity homoserine dehydrogenase activity

Pathway

KEGG	map00260 (EC 2.7.2.4) map00270 (EC 2.7.2.4) map00300 (EC 1.1.1.3)
MetaCyc	PWY-2941
Reactome	REACT_13 map00260 (EC 1.1.1.3) map00270 (EC 1.1.1.3) map00300 (EC 1.1.1.3)

Sequence

AT1G31230.1 | Genomic | mRNA | CDS | Protein

miRNA Interaction

Details


target: AT1G31230.1 miRNA: ath-miR414 miRNA: ath-miR414 mfe: -30.9 kcal/mol p-value: 0.001748 position: 1260 target 5' C A U A 3' GGC GA UGAUGAUGAAGAUGG CUG CU ACUACUACUUCUACU miRNA 3' A 5'

Ortholog Group

Ortholog Groups: OG5_128063

Accession	Taxon
NP_001031916	Arabidopsis thaliana
NP_001031917	Arabidopsis thaliana
NP_174408 ( AT1G31230 )	Arabidopsis thaliana
NP_193706	Arabidopsis thaliana
NP_197605	Arabidopsis thaliana
NP_974576	Arabidopsis thaliana
CMN129C	Cyanidioschyzon merolae strain 10D
196316	Chlamydomonas reinhardtii
196320	Chlamydomonas reinhardtii
196925	Chlamydomonas reinhardtii
ACO67207	Micromonas sp. RCC299
ACO69662	Micromonas sp. RCC299
NP_001061592	Oryza sativa Japonica Group
NP_001062794	Oryza sativa Japonica Group
NP_001065639	Oryza sativa Japonica Group
NP_001066044	Oryza sativa Japonica Group
fgenesh1_pg.C_Chr_09.0001000257	Ostreococcus tauri
e_gw1.194.11.1	Physcomitrella patens subsp. patens
e_gw1.88.230.1	Physcomitrella patens subsp. patens
e_gw1.88.38.1	Physcomitrella patens subsp. patens
29757.m000730	Ricinus communis
29942.m000731	Ricinus communis
50477.m000024	Ricinus communis
estExt_Genewise1.C_chr_70425	Thalassiosira pseudonana CCMP1335
estExt_Genewise1.C_chr_80132	Thalassiosira pseudonana CCMP1335
estExt_gwp_gw1.C_chr_50172	Thalassiosira pseudonana CCMP1335
XP_002947100	Volvox carteri f. nagariensis
XP_002958802	Volvox carteri f. nagariensis

Cross Link

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PIRSF	PIRSF000727	0.0	10	908	IPR011147	Bifunctional aspartokinase/homoserine dehydrogenase I
PANTHER	PTHR21499	0.0	74	911	No hit	NA
Pfam	PF00696	2.0E-44	84	366	IPR001048	Aspartate/glutamate/uridylate kinase
SUPERFAMILY	SSF53633	3.9E-70	84	380	IPR001048	Aspartate/glutamate/uridylate kinase
TIGRFAM	TIGR00657	4.0E-109	84	546	IPR001341	Aspartate kinase domain
ProSitePatterns	PS00324	NA	86	94	IPR018042	Aspartate kinase, conserved site
SUPERFAMILY	SSF55021	5.5E-19	392	466	No hit	NA
Pfam	PF01842	3.5E-10	410	465	IPR002912	ACT domain
SUPERFAMILY	SSF55021	2.6E-23	474	561	No hit	NA
Pfam	PF01842	3.6E-10	492	546	IPR002912	ACT domain
SUPERFAMILY	SSF51735	5.1E-38	551	725	No hit	NA
Pfam	PF03447	3.3E-23	559	695	IPR005106	Aspartate/homoserine dehydrogenase, NAD-binding
Pfam	PF00742	4.7E-54	703	901	IPR001342	Homoserine dehydrogenase, catalytic
SUPERFAMILY	SSF55347	3.3E-51	703	888	No hit	NA
ProSitePatterns	PS01042	NA	749	771	IPR019811	Homoserine dehydrogenase, conserved site
Coils	Coil	NA	804	825	No hit	NA

Subcellular Localization

Localization

plastid

Evidence

SUBAcon

Pubmed ID

23180787