Basic information
Locus name	AT5G41410
Alias	BEL1
Organism	Arabidopsis thaliana
Taxonomic identifier	[NCBI]
Function category	Transcription regulation:HB
Effect for Senescence	promote
Gene Description	Homeodomain protein (floral homeotic gene) required for ovule identity
Evidence	Genetic evidence:Mutant [Ref 1]; Genomic evidence:microarray data [Ref 2]
References	1: Ray A, Robinson-Beers K, Ray S, Baker SC, Lang JD, Preuss D, Milligan SB, Gasser CS Arabidopsis floral homeotic gene BELL (BEL1) controls ovule development through negative regulation of AGAMOUS gene (AG). Proc. Natl. Acad. Sci. U.S.A. 1994 Jun 21;91(13):5761-5 2: Buchanan-Wollaston V, Page T, Harrison E, Breeze E, Lim PO, Nam HG, Lin JF, Wu SH, Swidzinski J, Ishizaki K, Leaver CJ Comparative transcriptome analysis reveals significant differences in gene expression and signalling pathways between developmental and dark/starvation-induced senescence in Arabidopsis. Plant J. 2005 May;42(4):567-85
Gene Ontology	biological process regulation of transcription, DNA-dependent molecular function DNA binding sequence-specific DNA binding transcription factor activity sequence-specific DNA binding
Sequence	AT5G41410.1 | Genomic | mRNA | CDS | Protein
Mutant information
Mutant name	bel1-1
Mutant/Transgenic	mutant
Ecotype	Ler
Mutagenesis type	EMS
Microarray
Sampling	Buchanan-Wollaston V, Page T, Harrison E, Breeze E, Lim PO, Nam HG, Lin JF, Wu SH, Swidzinski J, Ishizaki K, Leaver CJ. Comparative transcriptome analysis reveals significant differences in gene expression and signalling pathways between developmental and dark/starvation-induced senescence in Arabidopsis. Plant J. 2005 May;42(4)
Comparation	Legends: Col: wild type, indicates the ratio of expression in senescing leaves/green leaves. NahG, coi1 and ein2: indicates the ratio of expression in senescing leaves of mutant/senescing wild type. D/L: ratio of DARK 5d/control. CD: Cell Death, ratio of starved cell suspension culture/control. Genes showing at least 3 fold (ratio) up regulation during leaf senescence.
miRNA Interaction
Details	target: AT5G41410.1  miRNA: ath-miR414 miRNA: ath-miR414 mfe: -34.1 kcal/mol  p-value: 0.000147  position:  877  target 5' A              U     A 3'             GAUGAUGAUGAUGA GAUGA              CUGCUACUACUACU CUACU   miRNA  3' A              U       5'  target: AT5G41410.1  miRNA: ath-miR866-3p miRNA: ath-miR866-3p mfe: -22.0 kcal/mol  p-value: 0.054774  position:  275  target 5' U                C    A 3'             UCUU GGAGAUGGGUU UUGU              AGAA UUUCUGCCUAA AACA   miRNA  3'      G                  5'
Ortholog Group
Ortholog Groups: OG5_188273	Accession Taxon NP_198957 ( AT5G41410 ) Arabidopsis thaliana NP_001056572 Oryza sativa Japonica Group 30190.m011257 Ricinus communis
Cross Link
Database Entry ID E-value Start End InterPro ID Description PANTHER PTHR11850 2.8E-99 54 514 No hit NA Pfam PF07526 5.5E-46 194 336 IPR006563 POX SMART SM00574 1.1E-71 200 338 IPR006563 POX Coils Coil NA 270 305 No hit NA ProSiteProfiles PS50071 12.0 389 452 IPR001356 Homeodomain SMART SM00389 5.6E-9 392 456 IPR001356 Homeodomain SUPERFAMILY SSF46689 3.4E-17 393 460 IPR009057 Homeodomain-like Pfam PF05920 1.7E-16 409 448 IPR008422 Homeobox KN domain
Subcellular Localization
Localization 1 Localization cytosol Evidence Localization with GFP-fusion protein (GFP:cDNA) Pubmed ID 10737809
Localization 2 Localization nucleus Evidence SUBAcon Pubmed ID 23180787