Basic information
Locus name	AT3G19190
Alias	ATG2
Organism	Arabidopsis thaliana
Taxonomic identifier	[NCBI]
Function category	Nutrient recycling:Autophagy
Effect for Senescence	delay
Gene Description	Encodes autophagy-related protein.
Evidence	Genetic evidence:Mutant [Ref 1]
References	1: Yoshimoto K, Jikumaru Y, Kamiya Y, Kusano M, Consonni C, Panstruga R, Ohsumi Y, Shirasu K Autophagy negatively regulates cell death by controlling NPR1-dependent salicylic acid signaling during senescence and the innate immune response in Arabidopsis. Plant Cell 2009 Sep;21(9):2914-27
Gene Ontology	biological process autophagy
Sequence	AT3G19190.1 | Genomic | mRNA | CDS | Protein
Mutant information
Mutated 1 Mutant name atg2 Mutant/Transgenic mutant Ecotype Col-0 Mutagenesis type T-DNA insertion_knock out
Mutated 2 Mutant name atg2pen2 Mutant/Transgenic mutant Ecotype Col-0 Mutagenesis type cross
miRNA Interaction
Details	target: AT3G19190.1  miRNA: ath-miR172a miRNA: ath-miR172a mfe: -28.5 kcal/mol  p-value: 0.019169  position:  3154  target 5' A     U              G 3'             AUGCG UGUCGUCAAGGUUC              UACGU GUAGUAGUUCUAAG   miRNA  3'       C              A 5'  target: AT3G19190.1  miRNA: ath-miR172b miRNA: ath-miR172b mfe: -28.5 kcal/mol  p-value: 0.017713  position:  3154  target 5' A     U              G 3'             AUGCG UGUCGUCAAGGUUC              UACGU GUAGUAGUUCUAAG   miRNA  3'       C              A 5'  target: AT3G19190.1  miRNA: ath-miR172c miRNA: ath-miR172c mfe: -28.2 kcal/mol  p-value: 0.022854  position:  3155  target 5' A    U              G 3'             UGCG UGUCGUCAAGGUUC              ACGU GUAGUAGUUCUAAG   miRNA  3' G    C              A 5'  target: AT3G19190.1  miRNA: ath-miR172d miRNA: ath-miR172d mfe: -28.2 kcal/mol  p-value: 0.023259  position:  3155  target 5' A    U              G 3'             UGCG UGUCGUCAAGGUUC              ACGU GUAGUAGUUCUAAG   miRNA  3' G    C              A 5'  target: AT3G19190.1  miRNA: ath-miR172e miRNA: ath-miR172e mfe: -28.3 kcal/mol  p-value: 0.022142  position:  3154  target 5' A     U              G 3'             AUGCG UGUCGUCAAGGUUC              UACGU GUAGUAGUUCUAAG   miRNA  3'       C              G 5'  target: AT3G19190.1  miRNA: ath-miR399f miRNA: ath-miR399f mfe: -28.1 kcal/mol  p-value: 0.034329  position:  3019  target 5' U    U  U             U 3'             CUGG GC GAUUUCUUUUGGU              GGCC CG UUAGAGGAAACCG   miRNA  3'         U             U 5'  target: AT3G19190.1  miRNA: ath-miR414 miRNA: ath-miR414 mfe: -28.4 kcal/mol  p-value: 0.006958  position:  918  target 5' G              U  C  C 3'             GAUGAUGAUGAUGA GG GA              CUGCUACUACUACU CU CU   miRNA  3' A              U  A    5'  target: AT3G19190.1  miRNA: ath-miR783 miRNA: ath-miR783 mfe: -24.1 kcal/mol  p-value: 0.119218  position:  459  target 5' U  G  U       U       G 3'             GA GU GACGAGC GGAGCUU              UU UA UUGCUCG UUUCGAA   miRNA  3' C  G  C                 5'  target: AT3G19190.1  miRNA: ath-miR832-5p miRNA: ath-miR832-5p mfe: -29.7 kcal/mol  p-value: 0.031567  position:  720  target 5' A                    A 3'             UUUGA UCCCGAUUUUGGCA              AAGCU AGGGCUAGGGUCGU   miRNA  3' A     A                5'  target: AT3G19190.1  miRNA: ath-miR867 miRNA: ath-miR867 mfe: -20.9 kcal/mol  p-value: 0.227606  position:  4345  target 5' A  G   A         G    A 3'             UU UAG AGACCAUGU UCAG              AG AUU UUUGGUACA AGUU   miRNA  3' A  G   A                5'
Ortholog Group
Ortholog Groups: OG5_130577	Accession Taxon NP_188550 ( AT3G19190 ) Arabidopsis thaliana ACO66210 Micromonas sp. RCC299 29801.m003197 Ricinus communis
Cross Link
Database Entry ID E-value Start End InterPro ID Description PANTHER PTHR13190 0.0 9 1837 IPR026849 Autophagy-related protein 2 Pfam PF12624 1.8E-11 21 123 IPR026854 Vacuolar protein sorting-associated protein 13A N-terminal domain Pfam PF13329 6.2E-5 1146 1212 IPR026885 Autophagy-related protein 2 CAD motif Pfam PF09333 2.1E-16 1734 1817 IPR015412 Autophagy-related, C-terminal
Mutant Image
atg2 (SALK_006994C) mutant exhibited early senescence phenotype compared with wild type Col-0 (7-week-old).