Basic information
Locus name	AT4G12570
Alias	UPL5
Organism	Arabidopsis thaliana
Taxonomic identifier	[NCBI]
Function category	Protein degradation/modification:E3 ubiquitin ligase
Effect for Senescence	delay
Gene Description	HECT domain E3 ubiquitin ligase
Evidence	Genetic evidence:Mutant [Ref 1]
References	1: Miao Y, Zentgraf U A HECT E3 ubiquitin ligase negatively regulates Arabidopsis leaf senescence through degradation of the transcription factor WRKY53. Plant J. 2010 Jul;63(2):179-88
Gene Ontology	biological process cellular protein modification process cellular component intracellular molecular function protein binding ubiquitin-protein ligase activity
Pathway	KEGG map00380 (EC 6.3.2.-)
Sequence	AT4G12570.1 | Genomic | mRNA | CDS | Protein
Mutant information
Mutated 1 Mutant name upl5-1 Mutant/Transgenic mutant Ecotype Col-0 Mutagenesis type T-DNA insertion_knock out
Mutated 2 Mutant name upl5-2 Mutant/Transgenic mutant Ecotype Col-0 Mutagenesis type T-DNA insertion_knock out
Ortholog Group
Ortholog Groups: OG5_170616	Accession Taxon NP_192994 ( AT4G12570 ) Arabidopsis thaliana NP_001063514 Oryza sativa Japonica Group e_gw1.148.7.1 Physcomitrella patens subsp. patens e_gw1.205.1.1 Physcomitrella patens subsp. patens 29206.m000140 Ricinus communis
Cross Link
Database Entry ID E-value Start End InterPro ID Description PANTHER PTHR11254 8.3E-267 1 871 No hit NA ProSiteProfiles PS50053 18.0 95 171 IPR019955 Ubiquitin supergroup SMART SM00213 4.7E-13 95 167 IPR000626 Ubiquitin SUPERFAMILY SSF54236 6.0E-18 96 183 No hit NA Pfam PF00240 1.6E-17 103 167 IPR000626 Ubiquitin PRINTS PR00348 1.4E-8 106 126 IPR019956 Ubiquitin subgroup PRINTS PR00348 1.4E-8 127 147 IPR019956 Ubiquitin subgroup PRINTS PR00348 1.4E-8 148 169 IPR019956 Ubiquitin subgroup SUPERFAMILY SSF56204 6.5E-90 507 859 IPR000569 HECT SMART SM00119 1.1E-64 530 871 IPR000569 HECT ProSiteProfiles PS50237 65.8 532 871 IPR000569 HECT Pfam PF00632 4.0E-65 560 860 IPR000569 HECT