Basic information
Locus name	AT5G15410
Alias	DND1
Organism	Arabidopsis thaliana
Taxonomic identifier	[NCBI]
Function category	Others:defense
Effect for Senescence	delay
Gene Description	defense, no death' gene (DND1) encodes a mutated cyclic nucleotide-gated cation channel; Same as CNGC2. plasma membrane-localized cation channel (CNGC2).
Evidence	Genetic evidence:Mutant [Ref 1]
References	1: Ma W, Smigel A, Walker RK, Moeder W, Yoshioka K, Berkowitz GA Leaf senescence signaling: the Ca2+-conducting Arabidopsis cyclic nucleotide gated channel2 acts through nitric oxide to repress senescence programming. Plant Physiol. 2010 Oct;154(2):733-43
Sequence	AT5G15410.1 | Genomic | mRNA | CDS | Protein AT5G15410.2 | Genomic | mRNA | CDS | Protein
Mutant information
Mutant name	dnd1
Mutant/Transgenic	mutant
Ecotype	Col-0
Mutagenesis type	EMS
Ortholog Group
Ortholog Groups: OG5_150351	Accession Taxon NP_197045 ( AT5G15410 ) Arabidopsis thaliana NP_200236 Arabidopsis thaliana NP_851188 Arabidopsis thaliana NP_974783 Arabidopsis thaliana NP_001051331 Oryza sativa Japonica Group NP_001055973 Oryza sativa Japonica Group fgenesh2_pg.scaffold_99000010 Physcomitrella patens subsp. patens gw1.90.40.1 Physcomitrella patens subsp. patens 28124.m000232 Ricinus communis 30027.m000817 Ricinus communis
Cross Link
Database Entry ID E-value Start End InterPro ID Description PANTHER PTHR10217 0.0 89 719 No hit NA SUPERFAMILY SSF81324 7.6E-24 114 318 No hit NA SUPERFAMILY SSF81324 7.6E-24 392 451 No hit NA SUPERFAMILY SSF51206 9.7E-35 457 644 IPR018490 Cyclic nucleotide-binding-like ProSiteProfiles PS50042 13.9 530 640 IPR000595 Cyclic nucleotide-binding domain SMART SM00100 2.3E-4 530 659 IPR000595 Cyclic nucleotide-binding domain Pfam PF00027 9.6E-11 549 643 IPR000595 Cyclic nucleotide-binding domain
Mutant Image
mutant plants showing early senescence
Subcellular Localization
Localization	plasma membrane
Evidence	SUBAcon
Pubmed ID	23180787