Basic information
Locus name	AT2G23150
Alias	NRAMP3
Organism	Arabidopsis thaliana
Taxonomic identifier	[NCBI]
Function category	Nutrient recycling
Effect for Senescence	unclear
Gene Description	NRAMP metal ion transporter 3 (NRAMP3) identical to metal transporter Nramp3 [Arabidopsis thaliana] gi|6468012|gb|AAF13278; member of the natural resistance-associated macrophage protein (NRAMP) metal transporter family, PMID:11500563
Evidence	Genomic evidence:microarray data [Ref 1]
References	1: Buchanan-Wollaston V, Page T, Harrison E, Breeze E, Lim PO, Nam HG, Lin JF, Wu SH, Swidzinski J, Ishizaki K, Leaver CJ Comparative transcriptome analysis reveals significant differences in gene expression and signalling pathways between developmental and dark/starvation-induced senescence in Arabidopsis. Plant J. 2005 May;42(4):567-85
Gene Ontology	biological process transport cellular component membrane molecular function transporter activity
Pathway	Reactome REACT_15518
Sequence	AT2G23150.1 | Genomic | mRNA | CDS | Protein
Microarray
Sampling	Buchanan-Wollaston V, Page T, Harrison E, Breeze E, Lim PO, Nam HG, Lin JF, Wu SH, Swidzinski J, Ishizaki K, Leaver CJ. Comparative transcriptome analysis reveals significant differences in gene expression and signalling pathways between developmental and dark/starvation-induced senescence in Arabidopsis. Plant J. 2005 May;42(4)
Comparation	Legends: Col: wild type, indicates the ratio of expression in senescing leaves/green leaves. NahG, coi1 and ein2: indicates the ratio of expression in senescing leaves of mutant/senescing wild type. D/L: ratio of DARK 5d/control. CD: Cell Death, ratio of starved cell suspension culture/control. Genes showing at least 3 fold (ratio) up regulation during leaf senescence.
miRNA Interaction
Details	target: AT2G23150.1  miRNA: ath-miR834 miRNA: ath-miR834 mfe: -28.9 kcal/mol  p-value: 0.008539  position:  463  target 5' A   G  G              A 3'             UUG UA UGCUAUUGCUAUCA              AAU GU GCGAUGACGAUGGU   miRNA  3'     G  G                5'  target: AT2G23150.1  miRNA: ath-miR865-5p miRNA: ath-miR865-5p mfe: -22.1 kcal/mol  p-value: 0.026060  position:  435  target 5' U              U     A 3'             UUGAUUGGAUCUGA AUUCA              AGUUAAUCUAGGUU UAAGU   miRNA  3' G                    A 5'
Ortholog Group
Ortholog Groups: OG5_127097	Accession Taxon NP_173048 Arabidopsis thaliana NP_175157 Arabidopsis thaliana NP_178198 Arabidopsis thaliana NP_179896 ( AT2G23150 ) Arabidopsis thaliana NP_193614 Arabidopsis thaliana NP_201534 Arabidopsis thaliana CML262C Cyanidioschyzon merolae strain 10D CMT180C Cyanidioschyzon merolae strain 10D 113049 Chlamydomonas reinhardtii 128400 Chlamydomonas reinhardtii ACO62827 Micromonas sp. RCC299 NP_001045794 Oryza sativa Japonica Group NP_001049330 Oryza sativa Japonica Group NP_001058349 Oryza sativa Japonica Group NP_001059312 Oryza sativa Japonica Group NP_001059315 Oryza sativa Japonica Group NP_001067135 Oryza sativa Japonica Group estExt_genewise1.C_Chr_15.00010089 Ostreococcus tauri e_gw1.139.20.1 Physcomitrella patens subsp. patens e_gw1.2.138.1 Physcomitrella patens subsp. patens estExt_fgenesh1_pg.C_10047 Physcomitrella patens subsp. patens estExt_gwp_gw1.C_370047 Physcomitrella patens subsp. patens 29588.m000852 Ricinus communis 29648.m002003 Ricinus communis 29648.m002004 Ricinus communis 29970.m001011 Ricinus communis 30170.m013772 Ricinus communis fgenesh1_pg.C_chr_14000185 Thalassiosira pseudonana CCMP1335 XP_002947173 Volvox carteri f. nagariensis XP_002955040 Volvox carteri f. nagariensis
Cross Link
Database Entry ID E-value Start End InterPro ID Description PANTHER PTHR11706 0.0 3 509 IPR001046 Natural resistance-associated macrophage like Hamap MF_00221 40.5 31 464 IPR001046 Natural resistance-associated macrophage like TIGRFAM TIGR01197 1.5E-131 54 432 IPR001046 Natural resistance-associated macrophage like Pfam PF01566 2.0E-112 78 438 IPR001046 Natural resistance-associated macrophage like PRINTS PR00447 3.9E-80 135 161 IPR001046 Natural resistance-associated macrophage like PRINTS PR00447 3.9E-80 165 184 IPR001046 Natural resistance-associated macrophage like PRINTS PR00447 3.9E-80 190 211 IPR001046 Natural resistance-associated macrophage like PRINTS PR00447 3.9E-80 239 262 IPR001046 Natural resistance-associated macrophage like PRINTS PR00447 3.9E-80 346 365 IPR001046 Natural resistance-associated macrophage like PRINTS PR00447 3.9E-80 374 391 IPR001046 Natural resistance-associated macrophage like PRINTS PR00447 3.9E-80 408 427 IPR001046 Natural resistance-associated macrophage like
Subcellular Localization
Localization	vacuole
Evidence	SUBAcon
Pubmed ID	23180787