Basic information
Locus name	AT5G44790
Alias	RAN1
Organism	Arabidopsis thaliana
Taxonomic identifier	[NCBI]
Function category	Hormone response pathway:ET
Effect for Senescence	unclear
Gene Description	copper-exporting ATPase / responsive-to-antagonist 1 / copper-transporting ATPase (RAN1) identical to SP|Q9S7J8
Evidence	Genomic evidence:microarray data [Ref 1]
References	1: Buchanan-Wollaston V, Page T, Harrison E, Breeze E, Lim PO, Nam HG, Lin JF, Wu SH, Swidzinski J, Ishizaki K, Leaver CJ Comparative transcriptome analysis reveals significant differences in gene expression and signalling pathways between developmental and dark/starvation-induced senescence in Arabidopsis. Plant J. 2005 May;42(4):567-85
Gene Ontology	biological process cation transport cellular component integral to membrane molecular function cation-transporting ATPase activity
Sequence	AT5G44790.1 | Genomic | mRNA | CDS | Protein
Microarray
Sampling	Buchanan-Wollaston V, Page T, Harrison E, Breeze E, Lim PO, Nam HG, Lin JF, Wu SH, Swidzinski J, Ishizaki K, Leaver CJ. Comparative transcriptome analysis reveals significant differences in gene expression and signalling pathways between developmental and dark/starvation-induced senescence in Arabidopsis. Plant J. 2005 May;42(4)
Comparation	Legends: Col: wild type, indicates the ratio of expression in senescing leaves/green leaves. NahG, coi1 and ein2: indicates the ratio of expression in senescing leaves of mutant/senescing wild type. D/L: ratio of DARK 5d/control. CD: Cell Death, ratio of starved cell suspension culture/control. Genes showing at least 3 fold (ratio) up regulation during leaf senescence.
miRNA Interaction
Details	target: AT5G44790.1  miRNA: ath-miR1886 miRNA: ath-miR1886 mfe: -18.1 kcal/mol  p-value: 0.717724  position:  806  target 5' G                G   G 3'             GGU GGAUGGGAUUUU AAU              UCA UCUACUUUAGAA UUA   miRNA  3'     U            A   A 5'
Ortholog Group
Ortholog Groups: OG5_126855	Accession Taxon NP_176533 Arabidopsis thaliana NP_199292 ( AT5G44790 ) Arabidopsis thaliana CMP215C Cyanidioschyzon merolae strain 10D 121438 Chlamydomonas reinhardtii 195962 Chlamydomonas reinhardtii 206047 Chlamydomonas reinhardtii ACO61854 Micromonas sp. RCC299 ACO63823 Micromonas sp. RCC299 NP_001046033 Oryza sativa Japonica Group NP_001046193 Oryza sativa Japonica Group NP_001053522 Oryza sativa Japonica Group NP_001058305 Oryza sativa Japonica Group estExt_gwp_GeneWisePlus.C_Chr_05.00010248 Ostreococcus tauri estExt_gwp_gw1.C_1840090 Physcomitrella patens subsp. patens fgenesh1_pg.scaffold_94000062 Physcomitrella patens subsp. patens 29840.m000632 Ricinus communis 30169.m006419 Ricinus communis 30190.m011197 Ricinus communis 30190.m011198 Ricinus communis thaps1_ua_kg.chr_16a000004 Thalassiosira pseudonana CCMP1335 thaps1_ua_kg.chr_7000008 Thalassiosira pseudonana CCMP1335 XP_002945987 Volvox carteri f. nagariensis XP_002958680 Volvox carteri f. nagariensis
Cross Link
Database Entry ID E-value Start End InterPro ID Description SUPERFAMILY SSF55008 1.0E-19 53 126 IPR006121 Heavy metal-associated domain, HMA PRINTS PR00942 4.1E-12 57 82 No hit NA ProSiteProfiles PS50846 22.8 57 123 IPR006121 Heavy metal-associated domain, HMA TIGRFAM TIGR00003 7.6E-13 57 121 IPR006122 Heavy metal-associated domain, copper ion-binding Pfam PF00403 8.6E-12 62 120 IPR006121 Heavy metal-associated domain, HMA ProSitePatterns PS01047 NA 62 92 IPR017969 Heavy-metal-associated, conserved site PRINTS PR00942 4.1E-12 83 106 No hit NA PANTHER PTHR24093 0.0 104 1001 IPR001757 Cation-transporting P-type ATPase PRINTS PR00942 4.1E-12 112 132 No hit NA ProSiteProfiles PS50846 22.1 134 200 IPR006121 Heavy metal-associated domain, HMA SUPERFAMILY SSF55008 7.9E-19 134 204 IPR006121 Heavy metal-associated domain, HMA TIGRFAM TIGR00003 4.9E-10 136 197 IPR006122 Heavy metal-associated domain, copper ion-binding Pfam PF00403 8.7E-12 137 197 IPR006121 Heavy metal-associated domain, HMA ProSitePatterns PS01047 NA 139 169 IPR017969 Heavy-metal-associated, conserved site PRINTS PR00942 4.1E-12 157 178 No hit NA SUPERFAMILY SSF55008 1.6E-7 203 271 IPR006121 Heavy metal-associated domain, HMA ProSiteProfiles PS50846 12.2 208 274 IPR006121 Heavy metal-associated domain, HMA TIGRFAM TIGR01525 5.6E-194 370 984 IPR027256 Cation-transporting P-type ATPase, subfamily IB SUPERFAMILY SSF81665 4.2E-11 401 440 No hit NA Pfam PF00122 2.6E-49 408 648 IPR008250 P-type ATPase, A domain TIGRFAM TIGR01494 1.6E-42 409 682 IPR001757 Cation-transporting P-type ATPase SUPERFAMILY SSF81653 4.2E-23 457 542 No hit NA PRINTS PR00119 3.0E-30 492 506 IPR001757 Cation-transporting P-type ATPase SUPERFAMILY SSF81665 4.2E-11 543 650 No hit NA Pfam PF00702 4.1E-50 652 889 IPR023214 HAD-like domain SUPERFAMILY SSF56784 8.8E-61 655 674 IPR023214 HAD-like domain PRINTS PR00119 3.0E-30 656 670 IPR001757 Cation-transporting P-type ATPase ProSitePatterns PS00154 NA 658 664 IPR018303 P-type ATPase, phosphorylation site SUPERFAMILY SSF56784 8.8E-61 732 981 IPR023214 HAD-like domain TIGRFAM TIGR01494 4.8E-50 739 954 IPR001757 Cation-transporting P-type ATPase PRINTS PR00119 3.0E-30 800 811 IPR001757 Cation-transporting P-type ATPase PRINTS PR00119 3.0E-30 822 832 IPR001757 Cation-transporting P-type ATPase PRINTS PR00119 3.0E-30 875 894 IPR001757 Cation-transporting P-type ATPase PRINTS PR00119 3.0E-30 898 910 IPR001757 Cation-transporting P-type ATPase SUPERFAMILY SSF81665 4.2E-11 924 959 No hit NA
Subcellular Localization
Localization	plasma membrane,golgi
Evidence	SUBAcon
Pubmed ID	23180787