Basic information
Locus name	AT3G63380
Organism	Arabidopsis thaliana
Taxonomic identifier	[NCBI]
Function category	Nutrient recycling
Effect for Senescence	unclear
Gene Description	calcium-transporting ATPase, plasma membrane-type, putative / Ca(2+)-ATPase, putative (ACA12) identical to SP|Q9LY77 Potential calcium-transporting ATPase 12, plasma membrane-type (EC 3.6.3.8) (Ca(2+)-ATPase isoform 12) {Arabidopsis thaliana}; similar to SP|Q9LF79 Calcium-transporting ATPase 8, plasma membrane-type (EC 3.6.3.8) (Ca2+-ATPase, isoform 8) {Arabidopsis thaliana}; contains InterPro Accession IPR006069: Cation transporting ATPase
Evidence	Genomic evidence:microarray data [Ref 1]
References	1: Buchanan-Wollaston V, Page T, Harrison E, Breeze E, Lim PO, Nam HG, Lin JF, Wu SH, Swidzinski J, Ishizaki K, Leaver CJ Comparative transcriptome analysis reveals significant differences in gene expression and signalling pathways between developmental and dark/starvation-induced senescence in Arabidopsis. Plant J. 2005 May;42(4):567-85
Gene Ontology	biological process cation transport cellular component integral to membrane molecular function cation-transporting ATPase activity
Sequence	AT3G63380.1 | Genomic | mRNA | CDS | Protein
Microarray
Sampling	Buchanan-Wollaston V, Page T, Harrison E, Breeze E, Lim PO, Nam HG, Lin JF, Wu SH, Swidzinski J, Ishizaki K, Leaver CJ. Comparative transcriptome analysis reveals significant differences in gene expression and signalling pathways between developmental and dark/starvation-induced senescence in Arabidopsis. Plant J. 2005 May;42(4)
Comparation	Legends: Col: wild type, indicates the ratio of expression in senescing leaves/green leaves. NahG, coi1 and ein2: indicates the ratio of expression in senescing leaves of mutant/senescing wild type. CD: Cell Death, ratio of starved cell suspension culture/control. Genes showing at least 3 fold (ratio) up regulation during leaf senescence.
miRNA Interaction
Details	target: AT3G63380.1  miRNA: ath-miR401 miRNA: ath-miR401 mfe: -27.5 kcal/mol  p-value: 0.030040  position:  652  target 5' U        U      U    U 3'             UGUUGGUC GCGCUA UUUC              ACAGCCAG UGUGGU AAAG   miRNA  3'          C      C    C 5'  target: AT3G63380.1  miRNA: ath-miR865-5p miRNA: ath-miR865-5p mfe: -20.3 kcal/mol  p-value: 0.152071  position:  2299  target 5' G     A              G 3'             UUGAU AGAUCCGGG UCAU              AGUUA UCUAGGUUU AGUA   miRNA  3' G     A         A      5'
Ortholog Group
Ortholog Groups: OG5_126645	Accession Taxon NP_179879 Arabidopsis thaliana NP_181687 Arabidopsis thaliana NP_188755 Arabidopsis thaliana NP_188931 Arabidopsis thaliana NP_191292 Arabidopsis thaliana NP_191897 ( AT3G63380 ) Arabidopsis thaliana NP_194719 Arabidopsis thaliana NP_195479 Arabidopsis thaliana NP_200113 Arabidopsis thaliana NP_200521 Arabidopsis thaliana NP_564295 Arabidopsis thaliana NP_849716 Arabidopsis thaliana NP_851200 Arabidopsis thaliana CMQ379C Cyanidioschyzon merolae strain 10D 118223 Chlamydomonas reinhardtii 128099 Chlamydomonas reinhardtii 189266 Chlamydomonas reinhardtii 196702 Chlamydomonas reinhardtii ACO69190 Micromonas sp. RCC299 ACO69913 Micromonas sp. RCC299 NP_001045345 Oryza sativa Japonica Group NP_001046064 Oryza sativa Japonica Group NP_001049307 Oryza sativa Japonica Group NP_001050661 Oryza sativa Japonica Group NP_001053795 Oryza sativa Japonica Group NP_001055932 Oryza sativa Japonica Group NP_001062241 Oryza sativa Japonica Group NP_001065710 Oryza sativa Japonica Group NP_001066105 Oryza sativa Japonica Group NP_001067159 Oryza sativa Japonica Group estExt_genewise1.C_Chr_09.00010003 Ostreococcus tauri e_gw1.34.2.1 Physcomitrella patens subsp. patens e_gw1.37.18.1 Physcomitrella patens subsp. patens estExt_Genewise1.C_2900008 Physcomitrella patens subsp. patens estExt_Genewise1.C_80210 Physcomitrella patens subsp. patens fgenesh2_pg.scaffold_92000008 Physcomitrella patens subsp. patens 29661.m000915 Ricinus communis 29661.m000916 Ricinus communis 29844.m003207 Ricinus communis 29844.m003208 Ricinus communis 29883.m001964 Ricinus communis 29937.m000200 Ricinus communis 30094.m000670 Ricinus communis 30128.m008598 Ricinus communis 30128.m008624 Ricinus communis 30162.m001261 Ricinus communis 30170.m013745 Ricinus communis 30198.m000878 Ricinus communis thaps1_ua_kg.chr_13000064 Thalassiosira pseudonana CCMP1335 XP_002948264 Volvox carteri f. nagariensis XP_002949457 Volvox carteri f. nagariensis XP_002954780 Volvox carteri f. nagariensis
Cross Link
Database Entry ID E-value Start End InterPro ID Description PANTHER PTHR24093 0.0 1 1015 IPR001757 Cation-transporting P-type ATPase TIGRFAM TIGR01517 2.5E-303 106 1006 IPR006408 Calcium-transporting P-type ATPase, subfamily IIB SMART SM00831 0.0 107 181 IPR004014 Cation-transporting P-type ATPase, N-terminal Pfam PF00690 2.8E-14 109 176 IPR004014 Cation-transporting P-type ATPase, N-terminal SUPERFAMILY SSF81665 9.4E-120 109 227 No hit NA Pfam PF00122 1.6E-63 195 443 IPR008250 P-type ATPase, A domain TIGRFAM TIGR01494 1.1E-18 196 367 IPR001757 Cation-transporting P-type ATPase SUPERFAMILY SSF81653 9.8E-26 227 326 No hit NA PRINTS PR00119 3.0E-34 275 289 IPR001757 Cation-transporting P-type ATPase SUPERFAMILY SSF81665 9.4E-120 328 445 No hit NA TIGRFAM TIGR01494 3.1E-22 392 481 IPR001757 Cation-transporting P-type ATPase Pfam PF00702 2.1E-26 448 763 IPR023214 HAD-like domain SUPERFAMILY SSF56784 3.3E-56 449 469 IPR023214 HAD-like domain PRINTS PR00119 3.0E-34 451 465 IPR001757 Cation-transporting P-type ATPase ProSitePatterns PS00154 NA 453 459 IPR018303 P-type ATPase, phosphorylation site SUPERFAMILY SSF81660 1.2E-40 457 654 IPR023299 P-type ATPase, cytoplasmic domain N SUPERFAMILY SSF56784 3.3E-56 602 854 IPR023214 HAD-like domain PRINTS PR00120 1.4E-11 605 623 IPR001757 Cation-transporting P-type ATPase PRINTS PR00119 3.0E-34 642 653 IPR001757 Cation-transporting P-type ATPase PRINTS PR00119 3.0E-34 664 674 IPR001757 Cation-transporting P-type ATPase TIGRFAM TIGR01494 6.6E-33 720 829 IPR001757 Cation-transporting P-type ATPase PRINTS PR00119 3.0E-34 749 768 IPR001757 Cation-transporting P-type ATPase PRINTS PR00120 1.4E-11 749 765 IPR001757 Cation-transporting P-type ATPase PRINTS PR00119 3.0E-34 773 785 IPR001757 Cation-transporting P-type ATPase PRINTS PR00120 1.4E-11 781 806 IPR001757 Cation-transporting P-type ATPase SUPERFAMILY SSF81665 9.4E-120 799 1006 No hit NA Pfam PF00689 3.5E-45 834 1004 IPR006068 Cation-transporting P-type ATPase, C-terminal
Subcellular Localization
Localization	plasma membrane
Evidence	SUBAcon
Pubmed ID	23180787