Basic information
Locus name	AT4G00900
Alias	ECA2
Organism	Arabidopsis thaliana
Taxonomic identifier	[NCBI]
Function category	Nutrient recycling
Effect for Senescence	unclear
Gene Description	calcium-transporting ATPase 2, endoplasmic reticulum-type (ECA2) nearly identical to SP|O23087 Calcium-transporting ATPase 2, endoplasmic reticulum-type (EC 3.6.3.8) {Arabidopsis thaliana}; contains InterPro Accession IPR006069: Cation transporting ATPase
Evidence	Genomic evidence:microarray data [Ref 1]
References	1: Buchanan-Wollaston V, Page T, Harrison E, Breeze E, Lim PO, Nam HG, Lin JF, Wu SH, Swidzinski J, Ishizaki K, Leaver CJ Comparative transcriptome analysis reveals significant differences in gene expression and signalling pathways between developmental and dark/starvation-induced senescence in Arabidopsis. Plant J. 2005 May;42(4):567-85
Gene Ontology	biological process cation transport cellular component integral to membrane molecular function cation-transporting ATPase activity
Sequence	AT4G00900.1 | Genomic | mRNA | CDS | Protein
Microarray
Sampling	Buchanan-Wollaston V, Page T, Harrison E, Breeze E, Lim PO, Nam HG, Lin JF, Wu SH, Swidzinski J, Ishizaki K, Leaver CJ. Comparative transcriptome analysis reveals significant differences in gene expression and signalling pathways between developmental and dark/starvation-induced senescence in Arabidopsis. Plant J. 2005 May;42(4)
Comparation	Legends: Col: wild type, indicates the ratio of expression in senescing leaves/green leaves. NahG, coi1 and ein2: indicates the ratio of expression in senescing leaves of mutant/senescing wild type. D/L: ratio of DARK 5d/control. CD: Cell Death, ratio of starved cell suspension culture/control. Genes showing at least 3 fold (ratio) up regulation during leaf senescence.
miRNA Interaction
Details	target: AT4G00900.1  miRNA: ath-miR414 miRNA: ath-miR414 mfe: -24.6 kcal/mol  p-value: 0.022255  position:  2232  target 5' A    A          U A    U 3'             UGAC GGUGAUGGUG G AUGA              ACUG CUACUACUAC U UACU   miRNA  3'                 U C      5'
Ortholog Group
Ortholog Groups: OG5_126674	Accession Taxon NP_172246 Arabidopsis thaliana NP_172259 Arabidopsis thaliana NP_191999 ( AT4G00900 ) Arabidopsis thaliana NP_563860 Arabidopsis thaliana CMM114C Cyanidioschyzon merolae strain 10D CMT241C Cyanidioschyzon merolae strain 10D 77047 Chlamydomonas reinhardtii ACO68577 Micromonas sp. RCC299 ACO69912 Micromonas sp. RCC299 NP_001049744 Oryza sativa Japonica Group NP_001051163 Oryza sativa Japonica Group 0300010474 Ostreococcus tauri estExt_Genewise1.C_2390013 Physcomitrella patens subsp. patens estExt_Genewise1.C_2480016 Physcomitrella patens subsp. patens estExt_Genewise1.C_800026 Physcomitrella patens subsp. patens estExt_gwp_gw1.C_380002 Physcomitrella patens subsp. patens estExt_gwp_gw1.C_780084 Physcomitrella patens subsp. patens 29742.m001369 Ricinus communis 30039.m000230 Ricinus communis 30170.m013599 Ricinus communis e_gw1.15.5.1 Thalassiosira pseudonana CCMP1335 e_gw1.4.39.1 Thalassiosira pseudonana CCMP1335 estExt_thaps1_ua_kg.C_chr_30127 Thalassiosira pseudonana CCMP1335 fgenesh1_pm.C_chr_1000049 Thalassiosira pseudonana CCMP1335 XP_002953236 Volvox carteri f. nagariensis XP_002958852 Volvox carteri f. nagariensis
Cross Link
Database Entry ID E-value Start End InterPro ID Description PANTHER PTHR24093 0.0 1 1050 IPR001757 Cation-transporting P-type ATPase SMART SM00831 8.7E-21 8 82 IPR004014 Cation-transporting P-type ATPase, N-terminal SUPERFAMILY SSF81665 3.5E-136 9 133 No hit NA Pfam PF00690 2.9E-21 10 77 IPR004014 Cation-transporting P-type ATPase, N-terminal Pfam PF00122 1.5E-67 101 358 IPR008250 P-type ATPase, A domain TIGRFAM TIGR01494 3.5E-18 101 291 IPR001757 Cation-transporting P-type ATPase Coils Coil NA 120 141 No hit NA SUPERFAMILY SSF81653 5.4E-29 135 245 No hit NA PRINTS PR00119 1.7E-40 183 197 IPR001757 Cation-transporting P-type ATPase SUPERFAMILY SSF81665 3.5E-136 249 360 No hit NA TIGRFAM TIGR01494 4.3E-21 304 389 IPR001757 Cation-transporting P-type ATPase PRINTS PR00121 1.7E-7 359 380 No hit NA Pfam PF00702 1.3E-28 363 739 IPR023214 HAD-like domain SUPERFAMILY SSF56784 4.9E-51 364 384 IPR023214 HAD-like domain PRINTS PR00119 1.7E-40 366 380 IPR001757 Cation-transporting P-type ATPase ProSitePatterns PS00154 NA 368 374 IPR018303 P-type ATPase, phosphorylation site SUPERFAMILY SSF81660 1.4E-50 373 621 IPR023299 P-type ATPase, cytoplasmic domain N SUPERFAMILY SSF56784 4.9E-51 557 829 IPR023214 HAD-like domain PRINTS PR00119 1.7E-40 617 628 IPR001757 Cation-transporting P-type ATPase PRINTS PR00119 1.7E-40 639 649 IPR001757 Cation-transporting P-type ATPase TIGRFAM TIGR01494 3.7E-36 698 810 IPR001757 Cation-transporting P-type ATPase PRINTS PR00119 1.7E-40 725 744 IPR001757 Cation-transporting P-type ATPase PRINTS PR00119 1.7E-40 749 761 IPR001757 Cation-transporting P-type ATPase SUPERFAMILY SSF81665 3.5E-136 775 1044 No hit NA Pfam PF00689 1.6E-46 810 1039 IPR006068 Cation-transporting P-type ATPase, C-terminal PRINTS PR00121 1.7E-7 981 1005 No hit NA
Subcellular Localization
Localization	endoplasmic reticulum
Evidence	SUBAcon
Pubmed ID	23180787