Basic information
Locus name	AT1G58030
Organism	Arabidopsis thaliana
Taxonomic identifier	[NCBI]
Function category	Nutrient recycling
Effect for Senescence	unclear
Gene Description	amino acid permease family protein similar to SP|P18581 Low-affinity cationic amino acid transporter-2 (CAT-2) (T-cell early activation protein) {Mus musculus}; contains Pfam profile PF00324: Amino acid permease
Evidence	Genomic evidence:microarray data [Ref 1]
References	1: Buchanan-Wollaston V, Page T, Harrison E, Breeze E, Lim PO, Nam HG, Lin JF, Wu SH, Swidzinski J, Ishizaki K, Leaver CJ Comparative transcriptome analysis reveals significant differences in gene expression and signalling pathways between developmental and dark/starvation-induced senescence in Arabidopsis. Plant J. 2005 May;42(4):567-85
Gene Ontology	biological process amino acid transmembrane transport cellular component membrane molecular function amino acid transmembrane transporter activity
Sequence	AT1G58030.1 | Genomic | mRNA | CDS | Protein
Microarray
Sampling	Buchanan-Wollaston V, Page T, Harrison E, Breeze E, Lim PO, Nam HG, Lin JF, Wu SH, Swidzinski J, Ishizaki K, Leaver CJ. Comparative transcriptome analysis reveals significant differences in gene expression and signalling pathways between developmental and dark/starvation-induced senescence in Arabidopsis. Plant J. 2005 May;42(4)
Comparation	Legends: Col: wild type, indicates the ratio of expression in senescing leaves/green leaves. NahG, coi1 and ein2: indicates the ratio of expression in senescing leaves of mutant/senescing wild type. D/L: ratio of DARK 5d/control. CD: Cell Death, ratio of starved cell suspension culture/control. Genes showing at least 3 fold (ratio) up regulation during leaf senescence.
miRNA Interaction
Details	target: AT1G58030.1  miRNA: ath-miR167d miRNA: ath-miR167d mfe: -29.6 kcal/mol  p-value: 0.009238  position:  1627  target 5' U                     C 3'             CCGG UCAUGUUGGUA CUUC              GGUC AGUACGACCGU GAAG   miRNA  3'      U           C    U 5'  target: AT1G58030.1  miRNA: ath-miR776 miRNA: ath-miR776 mfe: -21.1 kcal/mol  p-value: 0.130802  position:  443  target 5' G    A                G 3'             AGCA CAAUAGGAG CU GGA              UUGU GUUAUCUUC GA UCU   miRNA  3'      A         U  A     5'  target: AT1G58030.1  miRNA: ath-miR782 miRNA: ath-miR782 mfe: -27.0 kcal/mol  p-value: 0.010677  position:  1714  target 5' C   A                 G 3'             AAG AGC UCUAGGGUGUUUG              UUC UUG AGGUUCCACAAAC   miRNA  3'         U             A 5'
Ortholog Group
Ortholog Groups: OG5_126699	Accession Taxon NP_001154586 Arabidopsis thaliana NP_187022 Arabidopsis thaliana NP_198510 Arabidopsis thaliana NP_563754 Arabidopsis thaliana NP_849822 ( AT1G58030 ) Arabidopsis thaliana CME062C Cyanidioschyzon merolae strain 10D 205765 Chlamydomonas reinhardtii 206100 Chlamydomonas reinhardtii ACO67941 Micromonas sp. RCC299 NP_001047620 Oryza sativa Japonica Group NP_001050796 Oryza sativa Japonica Group NP_001064675 Oryza sativa Japonica Group NP_001067309 Oryza sativa Japonica Group e_gw1.15.00.109.1 Ostreococcus tauri e_gw1.360.2.1 Physcomitrella patens subsp. patens estExt_gwp_gw1.C_2300007 Physcomitrella patens subsp. patens 30072.m000947 Ricinus communis 30072.m000948 Ricinus communis 30174.m008769 Ricinus communis gw1.1.181.1 Thalassiosira pseudonana CCMP1335 gw1.10.71.1 Thalassiosira pseudonana CCMP1335 thaps1_ua_kg.chr_23000036 Thalassiosira pseudonana CCMP1335 thaps1_ua_kg.chr_4000246 Thalassiosira pseudonana CCMP1335 XP_002949048 Volvox carteri f. nagariensis XP_002953996 Volvox carteri f. nagariensis
Cross Link
Database Entry ID E-value Start End InterPro ID Description PANTHER PTHR11785 1.4E-224 20 631 IPR002293 Amino acid/polyamine transporter I PIRSF PIRSF006060 7.1E-72 37 624 IPR002293 Amino acid/polyamine transporter I Pfam PF13520 4.2E-54 48 427 No hit NA Pfam PF13906 7.3E-22 560 610 No hit NA
Subcellular Localization
Localization	vacuole
Evidence	SUBAcon
Pubmed ID	23180787