Basic information
Locus name	AT4G23700
Organism	Arabidopsis thaliana
Taxonomic identifier	[NCBI]
Function category	Nutrient recycling
Effect for Senescence	unclear
Gene Description	cation/hydrogen exchanger, putative (CHX17) similar to Na+/H+-exchanging protein slr1595 - Synechocystis sp., EMBL:D90902; monovalent cation:proton antiporter family 2 (CPA2) member, PMID:11500563
Evidence	Genomic evidence:microarray data [Ref 1]
References	1: Buchanan-Wollaston V, Page T, Harrison E, Breeze E, Lim PO, Nam HG, Lin JF, Wu SH, Swidzinski J, Ishizaki K, Leaver CJ Comparative transcriptome analysis reveals significant differences in gene expression and signalling pathways between developmental and dark/starvation-induced senescence in Arabidopsis. Plant J. 2005 May;42(4):567-85
Gene Ontology	biological process cation transport transmembrane transport cellular component integral to membrane molecular function solute:hydrogen antiporter activity
Sequence	AT4G23700.1 | Genomic | mRNA | CDS | Protein
Microarray
Sampling	Buchanan-Wollaston V, Page T, Harrison E, Breeze E, Lim PO, Nam HG, Lin JF, Wu SH, Swidzinski J, Ishizaki K, Leaver CJ. Comparative transcriptome analysis reveals significant differences in gene expression and signalling pathways between developmental and dark/starvation-induced senescence in Arabidopsis. Plant J. 2005 May;42(4)
Comparation	Legends: Col: wild type, indicates the ratio of expression in senescing leaves/green leaves. NahG, coi1 and ein2: indicates the ratio of expression in senescing leaves of mutant/senescing wild type. CD: Cell Death, ratio of starved cell suspension culture/control. Genes showing at least 3 fold (ratio) up regulation during leaf senescence.
miRNA Interaction
Details	target: AT4G23700.1  miRNA: ath-miR396a miRNA: ath-miR396a mfe: -24.2 kcal/mol  p-value: 0.063716  position:  1079  target 5' U                A   U 3'             UAGUU GAGAAAGUUG GGA              GUCAA UUCUUUCGAC CCU   miRNA  3'       G          A   U 5'  target: AT4G23700.1  miRNA: ath-miR396b miRNA: ath-miR396b mfe: -23.3 kcal/mol  p-value: 0.092053  position:  1080  target 5' U               A   U 3'             AGUU GAGAAAGUUG GGA              UCAA UUCUUUCGAC CCU   miRNA  3' U    G          A   U 5'  target: AT4G23700.1  miRNA: ath-miR830 miRNA: ath-miR830 mfe: -22.2 kcal/mol  p-value: 0.013943  position:  1126  target 5' C      G             U 3'             UACUUC UCUCAAG UGGUU              GUGAAG AGAGUUU AUCAA   miRNA  3'        A       U     U 5'  target: AT4G23700.1  miRNA: ath-miR854a miRNA: ath-miR854a mfe: -30.8 kcal/mol  p-value: 0.011456  position:  632  target 5' G                    G 3'             CUCCU UUCCUUGUCUUCAU              GAGGA GAGGGAUAGGAGUA   miRNA  3'       G              G 5'  target: AT4G23700.1  miRNA: ath-miR854b miRNA: ath-miR854b mfe: -30.8 kcal/mol  p-value: 0.012867  position:  632  target 5' G                    G 3'             CUCCU UUCCUUGUCUUCAU              GAGGA GAGGGAUAGGAGUA   miRNA  3'       G              G 5'  target: AT4G23700.1  miRNA: ath-miR854c miRNA: ath-miR854c mfe: -30.8 kcal/mol  p-value: 0.011376  position:  632  target 5' G                    G 3'             CUCCU UUCCUUGUCUUCAU              GAGGA GAGGGAUAGGAGUA   miRNA  3'       G              G 5'  target: AT4G23700.1  miRNA: ath-miR854d miRNA: ath-miR854d mfe: -30.8 kcal/mol  p-value: 0.012123  position:  632  target 5' G                    G 3'             CUCCU UUCCUUGUCUUCAU              GAGGA GAGGGAUAGGAGUA   miRNA  3'       G              G 5'  target: AT4G23700.1  miRNA: ath-miR854e miRNA: ath-miR854e mfe: -30.8 kcal/mol  p-value: 0.013285  position:  632  target 5' G                    G 3'             CUCCU UUCCUUGUCUUCAU              GAGGA GAGGGAUAGGAGUA   miRNA  3'       G              G 5'
Ortholog Group
Ortholog Groups: OG5_128196	Accession Taxon NP_001030975 Arabidopsis thaliana NP_172049 Arabidopsis thaliana NP_176599 Arabidopsis thaliana NP_178985 Arabidopsis thaliana NP_180750 Arabidopsis thaliana NP_188390 Arabidopsis thaliana NP_190940 Arabidopsis thaliana NP_194101 ( AT4G23700 ) Arabidopsis thaliana NP_198976 Arabidopsis thaliana NP_974866 Arabidopsis thaliana ACO67418 Micromonas sp. RCC299 NP_001044623 Oryza sativa Japonica Group NP_001054455 Oryza sativa Japonica Group NP_001055076 Oryza sativa Japonica Group NP_001055872 Oryza sativa Japonica Group NP_001066026 Oryza sativa Japonica Group NP_001067282 Oryza sativa Japonica Group estExt_fgenesh1_pm.C_1230004 Physcomitrella patens subsp. patens estExt_gwp_gw1.C_1620028 Physcomitrella patens subsp. patens 29693.m002037 Ricinus communis 29729.m002305 Ricinus communis 29992.m001414 Ricinus communis 30025.m000600 Ricinus communis 30025.m000601 Ricinus communis 30025.m000602 Ricinus communis 30180.m001058 Ricinus communis 30190.m010768 Ricinus communis 30190.m011351 Ricinus communis 30199.m000886 Ricinus communis fgenesh1_pg.C_chr_19a_19000052 Thalassiosira pseudonana CCMP1335 thaps1_ua_kg.chr_1000235 Thalassiosira pseudonana CCMP1335 thaps1_ua_kg.chr_1000338 Thalassiosira pseudonana CCMP1335
Cross Link
Database Entry ID E-value Start End InterPro ID Description PANTHER PTHR32468 0.0 1 819 No hit NA Pfam PF00999 4.7E-73 38 422 IPR006153 Cation/H+ exchanger
Subcellular Localization
Localization	plasma membrane
Evidence	SUBAcon
Pubmed ID	23180787