Basic information
Locus name	AT5G46180
Organism	Arabidopsis thaliana
Taxonomic identifier	[NCBI]
Function category	Nutrient recycling
Effect for Senescence	unclear
Gene Description	ornithine aminotransferase, putative / ornithine--oxo-acid aminotransferase, putative similar to SP|Q92413 Ornithine aminotransferase (EC 2.6.1.13) (Ornithine--oxo-acid aminotransferase) [Aspergillus nidulans] {Emericella nidulans}; contains Pfam profile PF00202: aminotransferase, class III
Evidence	Genomic evidence:microarray data [Ref 1]
References	1: Buchanan-Wollaston V, Page T, Harrison E, Breeze E, Lim PO, Nam HG, Lin JF, Wu SH, Swidzinski J, Ishizaki K, Leaver CJ Comparative transcriptome analysis reveals significant differences in gene expression and signalling pathways between developmental and dark/starvation-induced senescence in Arabidopsis. Plant J. 2005 May;42(4):567-85
Gene Ontology	molecular function pyridoxal phosphate binding transaminase activity
Pathway
Sequence	AT5G46180.1 | Genomic | mRNA | CDS | Protein
Microarray
Sampling	Buchanan-Wollaston V, Page T, Harrison E, Breeze E, Lim PO, Nam HG, Lin JF, Wu SH, Swidzinski J, Ishizaki K, Leaver CJ. Comparative transcriptome analysis reveals significant differences in gene expression and signalling pathways between developmental and dark/starvation-induced senescence in Arabidopsis. Plant J. 2005 May;42(4)
Comparation	Legends: Col: wild type, indicates the ratio of expression in senescing leaves/green leaves. NahG, coi1 and ein2: indicates the ratio of expression in senescing leaves of mutant/senescing wild type. D/L: ratio of DARK 5d/control. CD: Cell Death, ratio of starved cell suspension culture/control. Genes showing at least 3 fold (ratio) up regulation during leaf senescence.
miRNA Interaction
Details	target: AT5G46180.1  miRNA: ath-miR781 miRNA: ath-miR781 mfe: -21.1 kcal/mol  p-value: 0.156019  position:  849  target 5' A   C                C 3'             AAG UGU UAGAGAACUCUG              UUC AUA GUCUUUUGAGAU   miRNA  3' A       G            U 5'  target: AT5G46180.1  miRNA: ath-miR837-5p miRNA: ath-miR837-5p mfe: -23.0 kcal/mol  p-value: 0.063667  position:  552  target 5' U      U         A   G 3'             UGAAAC AGCAAGAAA UGG              ACUUUG UUGUUCUUU ACU   miRNA  3'        C         G   A 5'  target: AT5G46180.1  miRNA: ath-miR844 miRNA: ath-miR844 mfe: -22.7 kcal/mol  p-value: 0.021293  position:  173  target 5' G                     C 3'             AGC UAU GGCGGUCU GCCA              UCG AUA UCGUUAGA UGGU   miRNA  3'     A   U        A      5'
Ortholog Group
Ortholog Groups: OG5_126982	Accession Taxon NP_178175 Arabidopsis thaliana NP_199430 ( AT5G46180 ) Arabidopsis thaliana CML323C Cyanidioschyzon merolae strain 10D CMQ064C Cyanidioschyzon merolae strain 10D 139007 Chlamydomonas reinhardtii 195386 Chlamydomonas reinhardtii ACO66894 Micromonas sp. RCC299 NP_001050753 Oryza sativa Japonica Group NP_001054542 Oryza sativa Japonica Group gw1.14.00.110.1 Ostreococcus tauri e_gw1.4.76.1 Physcomitrella patens subsp. patens estExt_fgenesh1_pg.C_1260047 Physcomitrella patens subsp. patens estExt_gwp_gw1.C_3820036 Physcomitrella patens subsp. patens 29693.m001974 Ricinus communis 30169.m006332 Ricinus communis estExt_Genewise1.C_chr_40321 Thalassiosira pseudonana CCMP1335 estExt_thaps1_ua_kg.C_chr_230045 Thalassiosira pseudonana CCMP1335 XP_002945774 Volvox carteri f. nagariensis XP_002956824 Volvox carteri f. nagariensis
Cross Link
Database Entry ID E-value Start End InterPro ID Description PIRSF PIRSF000521 7.0E-17 1 446 No hit NA PANTHER PTHR11986 1.8E-257 37 451 IPR005814 Aminotransferase class-III TIGRFAM TIGR01885 3.2E-195 40 443 IPR010164 Ornithine aminotransferase SUPERFAMILY SSF53383 1.7E-122 52 443 IPR015424 Pyridoxal phosphate-dependent transferase Pfam PF00202 8.3E-109 62 388 IPR005814 Aminotransferase class-III ProSitePatterns PS00600 NA 262 299 IPR005814 Aminotransferase class-III
Subcellular Localization
Localization	mitochondrion
Evidence	SUBAcon
Pubmed ID	23180787