Basic information
Locus name	AT3G11410
Organism	Arabidopsis thaliana
Taxonomic identifier	[NCBI]
Function category	Protein degradation/modification:protein kinase and phosphatases
Effect for Senescence	unclear
Gene Description	protein phosphatase 2C, putative / PP2C, putative identical to protein phosphatase 2C (PP2C) GB:P49598 [Arabidopsis thaliana]; contains Pfam profile PF00481: Protein phosphatase 2C; identical to cDNA protein phosphatase 2C GI:633027
Evidence	Genomic evidence:microarray data [Ref 1]
References	1: Buchanan-Wollaston V, Page T, Harrison E, Breeze E, Lim PO, Nam HG, Lin JF, Wu SH, Swidzinski J, Ishizaki K, Leaver CJ Comparative transcriptome analysis reveals significant differences in gene expression and signalling pathways between developmental and dark/starvation-induced senescence in Arabidopsis. Plant J. 2005 May;42(4):567-85
Gene Ontology	biological process protein dephosphorylation molecular function catalytic activity protein serine/threonine phosphatase activity
Sequence	AT3G11410.1 | Genomic | mRNA | CDS | Protein
Microarray
Sampling	Buchanan-Wollaston V, Page T, Harrison E, Breeze E, Lim PO, Nam HG, Lin JF, Wu SH, Swidzinski J, Ishizaki K, Leaver CJ. Comparative transcriptome analysis reveals significant differences in gene expression and signalling pathways between developmental and dark/starvation-induced senescence in Arabidopsis. Plant J. 2005 May;42(4)
Comparation	Legends: Col: wild type, indicates the ratio of expression in senescing leaves/green leaves. NahG, coi1 and ein2: indicates the ratio of expression in senescing leaves of mutant/senescing wild type. D/L: ratio of DARK 5d/control. CD: Cell Death, ratio of starved cell suspension culture/control. Genes showing at least 3 fold (ratio) up regulation during leaf senescence.
miRNA Interaction
Details	target: AT3G11410.1  miRNA: ath-miR414 miRNA: ath-miR414 mfe: -24.8 kcal/mol  p-value: 0.009243  position:  1075  target 5' G    G   C A C            G 3'             UGAC GAU G A UGAUGAGGAUGA              ACUG CUA C U ACUACUUCUACU   miRNA  3'                             5'
Ortholog Group
Ortholog Groups: OG5_160101	Accession Taxon NP_172223 Arabidopsis thaliana NP_180499 Arabidopsis thaliana NP_187748 ( AT3G11410 ) Arabidopsis thaliana NP_200730 Arabidopsis thaliana NP_001044788 Oryza sativa Japonica Group NP_001049674 Oryza sativa Japonica Group 30143.m001179 Ricinus communis
Cross Link
Database Entry ID E-value Start End InterPro ID Description PANTHER PTHR13832 9.1E-193 41 394 IPR015655 Protein phosphatase 2C SMART SM00332 4.8E-104 92 387 IPR001932 Protein phosphatase 2C (PP2C)-like SUPERFAMILY SSF81606 7.3E-76 100 390 IPR001932 Protein phosphatase 2C (PP2C)-like Pfam PF00481 3.5E-68 106 382 IPR001932 Protein phosphatase 2C (PP2C)-like SMART SM00331 0.0 116 389 IPR001932 Protein phosphatase 2C (PP2C)-like ProSitePatterns PS01032 NA 137 145 IPR000222 Protein phosphatase 2C, manganese/magnesium aspartate binding site
Subcellular Localization
Localization	cytosol
Evidence	SUBAcon
Pubmed ID	23180787