Basic information
Locus name	AT1G72770
Organism	Arabidopsis thaliana
Taxonomic identifier	[NCBI]
Function category	Protein degradation/modification:protein kinase and phosphatases
Effect for Senescence	unclear
Gene Description	protein phosphatase 2C P2C-HA / PP2C P2C-HA (P2C-HA) identical to protein phosphatase 2C (AtP2C-HA) GB:AJ003119
Evidence	Genomic evidence:microarray data [Ref 1]
References	1: Buchanan-Wollaston V, Page T, Harrison E, Breeze E, Lim PO, Nam HG, Lin JF, Wu SH, Swidzinski J, Ishizaki K, Leaver CJ Comparative transcriptome analysis reveals significant differences in gene expression and signalling pathways between developmental and dark/starvation-induced senescence in Arabidopsis. Plant J. 2005 May;42(4):567-85
Gene Ontology	biological process protein dephosphorylation molecular function catalytic activity protein serine/threonine phosphatase activity
Sequence	AT1G72770.1 | Genomic | mRNA | CDS | Protein AT1G72770.2 | Genomic | mRNA | CDS | Protein
Microarray
Sampling	Buchanan-Wollaston V, Page T, Harrison E, Breeze E, Lim PO, Nam HG, Lin JF, Wu SH, Swidzinski J, Ishizaki K, Leaver CJ. Comparative transcriptome analysis reveals significant differences in gene expression and signalling pathways between developmental and dark/starvation-induced senescence in Arabidopsis. Plant J. 2005 May;42(4)
Comparation	Legends: Col: wild type, indicates the ratio of expression in senescing leaves/green leaves. NahG, coi1 and ein2: indicates the ratio of expression in senescing leaves of mutant/senescing wild type. D/L: ratio of DARK 5d/control. CD: Cell Death, ratio of starved cell suspension culture/control. Genes showing at least 3 fold (ratio) up regulation during leaf senescence.
miRNA Interaction
Details	target: AT1G72770.1  miRNA: ath-miR773 miRNA: ath-miR773 mfe: -26.8 kcal/mol  p-value: 0.021363  position:  1673  target 5' U       U            G 3'             AGA AAA GCUGGAGGCAAA              UCU UUU CGACCUUCGUUU   miRNA  3' C   G   U              5'  target: AT1G72770.1  miRNA: ath-miR847 miRNA: ath-miR847 mfe: -26.9 kcal/mol  p-value: 0.023122  position:  1808  target 5' G             C     U 3'             GUCAAG AGAAGA GAGUG              UAGUUC UCUUCU CUCAC   miRNA  3' G      U      C     U 5'  target: AT1G72770.2  miRNA: ath-miR773 miRNA: ath-miR773 mfe: -26.8 kcal/mol  p-value: 0.022190  position:  1669  target 5' U       U            G 3'             AGA AAA GCUGGAGGCAAA              UCU UUU CGACCUUCGUUU   miRNA  3' C   G   U              5'  target: AT1G72770.2  miRNA: ath-miR847 miRNA: ath-miR847 mfe: -26.9 kcal/mol  p-value: 0.023990  position:  1927  target 5' G             C     U 3'             GUCAAG AGAAGA GAGUG              UAGUUC UCUUCU CUCAC   miRNA  3' G      U      C     U 5'
Ortholog Group
Ortholog Groups: OG5_139205	Accession Taxon NP_001077815 Arabidopsis thaliana NP_001119448 Arabidopsis thaliana NP_173199 Arabidopsis thaliana NP_177421 ( AT1G72770 ) Arabidopsis thaliana NP_194338 Arabidopsis thaliana NP_200515 Arabidopsis thaliana 121320 Chlamydomonas reinhardtii NP_001043415 Oryza sativa Japonica Group NP_001056498 Oryza sativa Japonica Group gw1.311.62.1 Physcomitrella patens subsp. patens gw1.80.44.1 Physcomitrella patens subsp. patens 29706.m001323 Ricinus communis 29739.m003582 Ricinus communis 29912.m005309 Ricinus communis thaps1_ua_kg.chr_3000303 Thalassiosira pseudonana CCMP1335 XP_002951041 Volvox carteri f. nagariensis
Cross Link
Database Entry ID E-value Start End InterPro ID Description PANTHER PTHR13832 1.6E-165 177 511 IPR015655 Protein phosphatase 2C SMART SM00332 1.7E-104 179 499 IPR001932 Protein phosphatase 2C (PP2C)-like SUPERFAMILY SSF81606 4.2E-74 182 502 IPR001932 Protein phosphatase 2C (PP2C)-like Pfam PF00481 9.8E-63 193 494 IPR001932 Protein phosphatase 2C (PP2C)-like ProSitePatterns PS01032 NA 238 246 IPR000222 Protein phosphatase 2C, manganese/magnesium aspartate binding site
Subcellular Localization
Localization	cytosol
Evidence	SUBAcon
Pubmed ID	23180787