Basic information
Locus name	AT4G25390
Organism	Arabidopsis thaliana
Taxonomic identifier	[NCBI]
Function category	Protein degradation/modification:protein kinase and phosphatases
Effect for Senescence	unclear
Gene Description	protein kinase family protein contains protein kinase domain, Pfam:PF00069
Evidence	Genomic evidence:microarray data [Ref 1]
References	1: Buchanan-Wollaston V, Page T, Harrison E, Breeze E, Lim PO, Nam HG, Lin JF, Wu SH, Swidzinski J, Ishizaki K, Leaver CJ Comparative transcriptome analysis reveals significant differences in gene expression and signalling pathways between developmental and dark/starvation-induced senescence in Arabidopsis. Plant J. 2005 May;42(4):567-85
Gene Ontology	biological process protein phosphorylation molecular function ATP binding protein kinase activity protein serine/threonine kinase activity
Sequence	AT4G25390.1 | Genomic | mRNA | CDS | Protein AT4G25390.2 | Genomic | mRNA | CDS | Protein
Microarray
Sampling	Buchanan-Wollaston V, Page T, Harrison E, Breeze E, Lim PO, Nam HG, Lin JF, Wu SH, Swidzinski J, Ishizaki K, Leaver CJ. Comparative transcriptome analysis reveals significant differences in gene expression and signalling pathways between developmental and dark/starvation-induced senescence in Arabidopsis. Plant J. 2005 May;42(4)
Comparation	Legends: Col: wild type, indicates the ratio of expression in senescing leaves/green leaves. NahG, coi1 and ein2: indicates the ratio of expression in senescing leaves of mutant/senescing wild type. D/L: ratio of DARK 5d/control. CD: Cell Death, ratio of starved cell suspension culture/control. Genes showing at least 3 fold (ratio) up regulation during leaf senescence.
miRNA Interaction
Details	target: AT4G25390.1  miRNA: ath-miR837-5p miRNA: ath-miR837-5p mfe: -22.2 kcal/mol  p-value: 0.110634  position:  1337  target 5' A A    U           A   U 3'             G AGAC AGCAAGAGACU GAU              C UUUG UUGUUCUUUGA CUA   miRNA  3' A      C                 5'  target: AT4G25390.1  miRNA: ath-miR847 miRNA: ath-miR847 mfe: -25.9 kcal/mol  p-value: 0.031226  position:  1369  target 5' U                     G 3'             CAUU GGAGGAAGAGGA UGA              GUAG UCUUCUUCUCCU ACU   miRNA  3'      U            C     5'  target: AT4G25390.2  miRNA: ath-miR837-5p miRNA: ath-miR837-5p mfe: -22.2 kcal/mol  p-value: 0.089031  position:  1337  target 5' A A    U           A   U 3'             G AGAC AGCAAGAGACU GAU              C UUUG UUGUUCUUUGA CUA   miRNA  3' A      C                 5'  target: AT4G25390.2  miRNA: ath-miR847 miRNA: ath-miR847 mfe: -25.9 kcal/mol  p-value: 0.024431  position:  1369  target 5' U                     G 3'             CAUU GGAGGAAGAGGA UGA              GUAG UCUUCUUCUCCU ACU   miRNA  3'      U            C     5'
Ortholog Group
Ortholog Groups: OG5_190440	Accession Taxon NP_194269 ( AT4G25390 ) Arabidopsis thaliana NP_199990 Arabidopsis thaliana NP_849442 Arabidopsis thaliana
Cross Link
Database Entry ID E-value Start End InterPro ID Description PANTHER PTHR24420 1.2E-131 1 270 No hit NA SUPERFAMILY SSF56112 6.0E-47 73 254 IPR011009 Protein kinase-like domain ProSiteProfiles PS50011 23.6 99 447 IPR000719 Protein kinase, catalytic domain SMART SM00220 1.5E-10 99 415 IPR002290 Serine/threonine- / dual specificity protein kinase, catalytic domain Pfam PF07714 9.4E-26 102 253 IPR001245 Serine-threonine/tyrosine-protein kinase catalytic domain ProSitePatterns PS00107 NA 105 127 IPR017441 Protein kinase, ATP binding site ProSitePatterns PS00108 NA 221 233 IPR008271 Serine/threonine-protein kinase, active site Coils Coil NA 428 449 No hit NA
Subcellular Localization
Localization 1 Localization nucleus Evidence SUBAcon Pubmed ID 23180787
Localization 2 Localization nucleus,plasma membrane Evidence SUBAcon Pubmed ID 23180787