Basic information
Locus name	AT5G58350
Organism	Arabidopsis thaliana
Taxonomic identifier	[NCBI]
Function category	Protein degradation/modification:protein kinase and phosphatases
Effect for Senescence	unclear
Gene Description	protein kinase family protein contains protein kinase domain, Pfam:PF00069
Evidence	Genomic evidence:microarray data [Ref 1]
References	1: Buchanan-Wollaston V, Page T, Harrison E, Breeze E, Lim PO, Nam HG, Lin JF, Wu SH, Swidzinski J, Ishizaki K, Leaver CJ Comparative transcriptome analysis reveals significant differences in gene expression and signalling pathways between developmental and dark/starvation-induced senescence in Arabidopsis. Plant J. 2005 May;42(4):567-85
Gene Ontology	biological process protein phosphorylation molecular function ATP binding protein kinase activity protein serine/threonine kinase activity
Sequence	AT5G58350.1 | Genomic | mRNA | CDS | Protein
Microarray
Sampling	Buchanan-Wollaston V, Page T, Harrison E, Breeze E, Lim PO, Nam HG, Lin JF, Wu SH, Swidzinski J, Ishizaki K, Leaver CJ. Comparative transcriptome analysis reveals significant differences in gene expression and signalling pathways between developmental and dark/starvation-induced senescence in Arabidopsis. Plant J. 2005 May;42(4)
Comparation	Legends: Col: wild type, indicates the ratio of expression in senescing leaves/green leaves. NahG, coi1 and ein2: indicates the ratio of expression in senescing leaves of mutant/senescing wild type. D/L: ratio of DARK 5d/control. CD: Cell Death, ratio of starved cell suspension culture/control. Genes showing at least 3 fold (ratio) up regulation during leaf senescence.
miRNA Interaction
Details	target: AT5G58350.1  miRNA: ath-miR837-5p miRNA: ath-miR837-5p mfe: -22.9 kcal/mol  p-value: 0.092091  position:  821  target 5' A C   C             G 3'             G AAU GACGAGAAGCUGG              C UUG UUGUUCUUUGACU   miRNA  3' A U   C             A 5'
Ortholog Group
Ortholog Groups: OG5_170755	Accession Taxon NP_200643 ( AT5G58350 ) Arabidopsis thaliana NP_566954 Arabidopsis thaliana NP_001065981 Oryza sativa Japonica Group 29044.m000164 Ricinus communis 29804.m001481 Ricinus communis
Cross Link
Database Entry ID E-value Start End InterPro ID Description PANTHER PTHR13902 8.0E-232 7 426 No hit NA ProSiteProfiles PS50011 39.5 19 277 IPR000719 Protein kinase, catalytic domain SMART SM00220 3.7E-56 19 277 IPR002290 Serine/threonine- / dual specificity protein kinase, catalytic domain Pfam PF00069 5.6E-50 21 277 IPR000719 Protein kinase, catalytic domain SUPERFAMILY SSF56112 1.2E-64 21 278 IPR011009 Protein kinase-like domain ProSitePatterns PS00108 NA 143 155 IPR008271 Serine/threonine-protein kinase, active site SUPERFAMILY SSF56112 1.2E-64 432 462 IPR011009 Protein kinase-like domain
Subcellular Localization
Localization 1 Localization nucleus Evidence Localization with GFP-fusion protein (GFP:cDNA) Pubmed ID 10737809
Localization 2 Localization cytoplasm and nucleus Evidence Localization with GFP-ORF fusion protein (GFP:cDNA) Pubmed ID 15610358
Localization 3 Localization cytosol Evidence SUBAcon Pubmed ID 23180787