DogPD allows users to browse GWAS curated data (e.g phenotype, alleles), breed and disease information.
1.1 Phenotype, Alleles & Disease
The phenotype, alleles and disease information is curated from public papers. The information includes chromosome, position, dbSNP rsid, species/population, disease trait, effect allele, OR value, P value, reported gene symbol and PMID.
DogPD collects breed information from 5 websites: AKC, UKC, CKC, UC, FCI and Wikipedia. The name of the breed is included and basic information of each breed is curated manually. DogPD provides three categories to browse the data: breed group, breed name from A to Z, and the geographic distribution of breed.
1.2.1 Breed Group
DogPD provides 10 types of breed group. The information is curated manually from the 5 websites mentioned above. Users can click on each group to show a breed list.
1.2.2 Dog Breeds A to Z
The breed names are ordered from A to Z. Users can click an interested letter to show all breed names starting with that letter. For example, clicking “A”, would show all breed names starting “A”.
1.2.3 Dog Breed of the World
DogPD includes 5 continents: Europe, America, Asia, Africa and Oceania. Clicking on a country from a continent will show the breed list of that origin.
1.2.4 The detail information of breed
Clicking a breed name will show detailed information in 6 categories.
a) General information: introduces the personality, energy level, shedding, grooming and other basic information of this breed. Other names of the breed will also be included.
b) Breed registries: shows if the breed is recognized by any international kennel clubs.
c) Associated disease: includes this breed’s disease name, the associated gene and disease level information.
d) Associated SNP information includes the SNP information from DogSD associated with this breed.
e) Breed standards includes the breed standard file provided by registered international kennel clubs.
f) Reference: includes the information sources of this breed.
DogPD provides dog disease information for users. The disease information is integrated from several websites such as OMIA, CIDD and the dog place.
The disease list includes the disease name, disease description, the associated gene and reference papers.
1.3.1 The Disease Detail Information
The disease detail information includes the basic information, associated disease in other database such as OMIA, and the associated breeds.
In basic information, we provide the disease description, inherit mode, disease symptom, disease cause and other information curated manually from public disease resource. User can click the link of the disease description to access the source.
Associated Disease provides the disease information curate from the OMIA database.
Associated Breeds provides the information of breeds that also have this disease.
DogPD provides several useful searching interfaces for users to require data.
2.1 Phenotype, Alleles & Disease
Users can search the phenotype, alleles & disease information by genome location, gene information and disease trait.
Users can search breed by breed name, temperament, size, trainability, weight, height, life expectancy, whether the breed is good with children, grooming and shedding frequencies.
Users can search the disease information by disease name, breed name, gene symbol, gene name and genome location.