The detail information of Deafness, LOXHD1-related
OMIA Basic Information
Possible human homologues (MIM numbers):
Mendelian trait/disorder: yes
Mode of inheritance: Autosomal Recessive
Considered a defect: yes
Year key mutation first reported: 2021
Species-specific name: Nonsyndromic hearing loss
Species-specific symbol: -
More detail information can see in
Associated Breeds
There are associated breeds.
Associated Gene
| Symbol | Description | Species | Position | Other Links |
|---|---|---|---|---|
| LOXHD1 | lipoxygenase homology domains 1 | Canis lupus familiaris | Chr7 : 44615788 - 44781462 | Homologene, Ensembl, NCBI gene |
References
Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.
| 2021 |
Hytönen,M.K.,Niskanen,J.E.,Arumilli,M.,Brookhart-Knox,C.A.,Donner,J.,Lohi,H.: :
Missense variant in LOXHD1 is associated with canine nonsyndromic hearing loss. Hum Genet :, 2021. Pubmed reference: 33983508 . DOI: 10.1007/s00439-021-02286-z . |
| 2001 |
Coppens,A.G.,Kiss,R.,Heizmann,C.W.,Deltenre,P.,Poncelet,L.: :
An original inner ear neuroepithelial degeneration in a deaf Rottweiler puppy. Hear Res 161:65-71, 2001. Pubmed reference: 11744282 . DOI: 10.1016/s0378-5955(01)00354-9 . |
| 1996 |
Strain,G.M.: :
Aetiology, prevalence and diagnosis of deafness in dogs and cats [Review] British Veterinary Journal 152:17-36, 1996. Pubmed reference: 8634862 . |