| Data Item | Number |
|---|---|
| Total genes | 140,356 |
| Total transcripts | 268,848 |
| Transcripts integrated from existing databases | 246,135 |
| Novel transcripts identified based on RNA-Seq data | 21,815 |
| Functional lncRNAs supported by experimental evidence | 1,867 |
| Item | Data | Results |
|---|---|---|
| Expression | HPA: 32 normal tissues, 122 samples GTEx: 53 normal tissues, 11,688 samples |
101,123 expressed lncRNA transcripts; 819 HK lncRNAs, 49,115 TS lncRNAs |
| Methylation |
TCGA: 9 cancers, 47 samples ENCODE: brain tissue, 1 sample |
Both promoter and body region methylation level of 270,044 lncRNA transcripts |
| Variation | 1000 Genomes Project dbSNP (Version 2017.07.10) |
92,725,757 SNPs |
| Interaction | 270,044 lncRNAs | 128,392,451 lncRNA-miRNA interactions |
| Data Item | LncRNA Number | Association Number | Literature Number |
|---|---|---|---|
| LncRNA-function association | 1,653 | 3,762 | 2,501 |
| LncRNA-disease association | 1,502 | 3,772 | 2,337 |
| MeSH Ontology | Association Number | LncRNA Number |
|---|---|---|
| Neoplasms | 2,888 | 1,077 |
| Digestive System Diseases | 888 | 427 |
| Male Urogenital Diseases | 423 | 176 |
| Female Urogenital Diseases and Pregnancy Complications | 403 | 195 |
| Respiratory Tract Diseases | 339 | 224 |
| Skin and Connective Tissue Diseases | 229 | 165 |
| Endocrine System Diseases | 260 | 129 |
| Cardiovascular Diseases | 242 | 155 |
| Congenital, Hereditary, and Neonatal Diseases and Abnormalities | 217 | 150 |
| Nervous System Diseases | 214 | 103 |
| Immune System Diseases | 126 | 69 |
| Hemic and Lymphatic Diseases | 117 | 63 |
| Mental Disorders | 101 | 52 |
| Musculoskeletal Diseases | 81 | 66 |
| Nutritional and Metabolic Diseases | 57 | 36 |
| Stomatognathic Diseases | 48 | 34 |
| Otorhinolaryngologic Diseases | 43 | 31 |
| Virus Diseases | 38 | 25 |
| Pathological Conditions, Signs and Symptoms | 24 | 21 |
| Eye Diseases | 19 | 11 |
| Bacterial Infections and Mycoses | 11 | 11 |
| Physiological Phenomena | 9 | 5 |
| Behavior and Behavior Mechanisms | 8 | 7 |
| Cell Physiological Phenomena | 5 | 4 |
| Chemically-Induced Disorders | 5 | 3 |
| Parasitic Diseases | 5 | 2 |
| Occupational Diseases | 3 | 3 |
| Disorders of Environmental Origin | 2 | 2 |
| Data Item | Association Number | LncRNA Number | |
|---|---|---|---|
| Functional Mechanism (n =6) | transcriptional regulation | 397 | 235 |
| ceRNA | 182 | 93 | |
| translational control | 19 | 17 | |
| splicing regulation | 19 | 9 | |
| protein localization | 6 | 6 | |
| RNAi | 3 | 3 | |
| Biological Process (n = 2) | pathogenic process | 3,598 | 1,502 |
| developmental process | 53 | 48 | |
| Tag (n = 8) | biomarker | 943 | 523 |
| therapy target | 373 | 196 | |
| snp in lncRNA | 144 | 84 | |
| oncogene | 113 | 62 | |
| suppressor | 104 | 58 | |
| stress action | 12 | 12 | |
| miRNA precursor | 7 | 7 | |
| evolution | 2 | 2 |