scMlnet2.0 scMLnet2.0: Single-cell RNA-seq data-based inference of multilayer inter- and intra-cellular signaling networks
Introduction
scMLnet2.0 is a development release of scMLnet R package developed to construct inter-/intracellular multilayer singaling network based on single-cell RNA-seq expression data. scMLnet constructs the multilayer network by integrating intercellular pathways (ligand-receptor interactions) and intracellular subnetworks (receptor-TF pathways and TF-target gene interactions) based on cell-type specific gene expression, prior network information and statistical inference.
Publications
Credits
- Xiaoqiang Sun sunxq6@mail.sysu.edu.cn Investigator
School of Mathematics, Sun Yat-sen University, China
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Summary
Accession | BT007419 |
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Tool Type | Toolkit |
Category | Intercellular signaling data |
Platforms | Windows |
Technologies | R |
User Interface | Terminal Command Line |
Latest Release | scMLnet2.0 (February 23, 2024) |
Download Count | 512 |
Country/Region | China |
Submitted By | Xiaoqiang Sun |
Fundings
National Key R&D Program of China (2021YFF1200903)