The detail information of Subaortic stenosis
OMIA Basic Information

Possible human homologues (MIM numbers):

Mendelian trait/disorder: yes

Mode of inheritance: Autosomal Recessive

Considered a defect: yes

Year key mutation first reported: -

Species-specific name: -

Species-specific symbol: -

More detail information can see in

Associated Breeds
iDog Breed Number Breed Name Personality Height Weight History Breed Source
CB166 Newfoundland 71.1 cm (male), 66 cm (female) 59-68 kg (male), 45.4-54.4 kg (female) Canada
Associated Gene
There are no associated genes.
References
Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.
2021 Ontiveros,E.S.,Stern,J.A.: :
Genetics of canine subvalvular aortic stenosis (SAS). Canine Med Genet 8:4, 2021.
Pubmed reference: 33962679 . DOI: 10.1186/s40575-021-00103-4 .
2020 Brambilla,P.G.,Polli,M.,Pradelli,D.,Papa,M.,Rizzi,R.,Bagardi,M.,Bussadori,C.: :
Epidemiological study of congenital heart diseases in dogs: Prevalence, popularity, and volatility throughout twenty years of clinical practice. PLoS One 15:e0230160, 2020.
Pubmed reference: 32716943 . DOI: 10.1371/journal.pone.0230160 .
2015 Drögemüller,M.,Jagannathan,V.,Dolf,G.,Butenhoff,K.,Kottmann-Berger,S.,Wess,G.,Leeb,T.: :
A single codon insertion in the PICALM gene is not associated with subvalvular aortic stenosis in Newfoundland dogs. Hum Genet 134:127-9, 2015.
Pubmed reference: 25391634 . DOI: 10.1007/s00439-014-1506-5 .
2015 Kander,M.,Pasławska,U.,Staszczyk,M.,Cepiel,A.,Pasławski,R.,Mazur,G.,Noszczyk-Nowak,A.: :
Retrospective analysis of co-occurrence of congenital aortic stenosis and pulmonary artery stenosis in dogs. Pol J Vet Sci 18:841-5, 2015.
Pubmed reference: 26812828 . DOI: 10.1515/pjvs-2015-0109 .
2014 Eason,B.D.,Fine,D.M.,Leeder,D.,Stauthammer,C.,Lamb,K.,Tobias,A.H.: :
Influence of Beta Blockers on Survival in Dogs with Severe Subaortic Stenosis. J Vet Intern Med :, 2014.
Pubmed reference: 24597738 . DOI: 10.1111/jvim.12339 .
2014 Stern,J.A.,White,S.N.,Lehmkuhl,L.B.,Reina-Doreste,Y.,Ferguson,J.L.,Nascone-Yoder,N.M.,Meurs,K.M.: :
A single codon insertion in PICALM is associated with development of familial subvalvular aortic stenosis in Newfoundland dogs. Hum Genet 133:1139-48, 2014.
Pubmed reference: 24898977 . DOI: 10.1007/s00439-014-1454-0 .
2013 Ohad,D.G.,Avrahami,A.,Waner,T.,David,L.: :
The occurrence and suspected mode of inheritance of congenital subaortic stenosis and tricuspid valve dysplasia in Dogue de Bordeaux dogs. Vet J 197:351-7, 2013.
Pubmed reference: 23434219 . DOI: 10.1016/j.tvjl.2013.01.012 .
2012 Reist-Marti,S.B.,Dolf,G.,Leeb,T.,Kottmann,S.,Kietzmann,S.,Butenhoff,K.,Rieder,S.: :
Genetic evidence of subaortic stenosis in the Newfoundland dog. Vet Rec 170:597, 2012.
Pubmed reference: 22645160 . DOI: 10.1136/vr.100019 .
2011 Oliveira,P.,Domenech,O.,Silva,J.,Vannini,S.,Bussadori,R.,Bussadori,C.: :
Retrospective Review of Congenital Heart Disease in 976 Dogs. J Vet Intern Med :, 2011.
Pubmed reference: 21418326 . DOI: 10.1111/j.1939-1676.2011.0711.x .
2010 Quintavalla,C.,Guazzetti,S.,Mavropoulou,A.,Bussadori,C.: :
Aorto-septal angle in Boxer dogs with subaortic stenosis: An echocardiographic study. Vet J 185:332-337, 2010.
Pubmed reference: 19665399 . DOI: 10.1016/j.tvjl.2009.06.027 .
2009 Jenni,S.,Gardelle,O.,Zini,E.,Glaus,TM.: :
Use of auscultation and Doppler echocardiography in Boxer puppies to predict development of subaortic or pulmonary stenosis. J Vet Intern Med 23:81-6, 2009.
Pubmed reference: 19175725 . DOI: 10.1111/j.1939-1676.2008.0213.x .
2006 Chetboul,V.,Trollé,J.M.,Nicolle,A.,CarlosSampedrano,C.,Gouni,V.,Laforge,H.,Benalloul,T.,Tissier,R.,Pouchelon,J.L.: :
Congenital heart diseases in the boxer dog: A retrospective study of 105 cases (1998-2005). J Vet Med A Physiol Pathol Clin Med 53:346-51, 2006.
Pubmed reference: 16922831 . DOI: 10.1111/j.1439-0442.2006.00865.x .
2005 Freedom,RM.,Yoo,SJ.,Russell,J.,Perrin,D.,Williams,WG.: :
Thoughts about fixed subaortic stenosis in man and dog. Cardiol Young 15:186-205, 2005.
Pubmed reference: 15845164 . DOI: 10.1017/S1047951105000399 .
2003 Baumgartner,C.,Glaus,TM.: :
[Congenital cardiac diseases in dogs: a retrospective analysis]. Schweiz Arch Tierheilkd 145:527-33, 535-6, 2003.
Pubmed reference: 14639823 .
2000 Orton,E.C.,Herndon,G.D.,Boon,J.A.,Gaynor,J.S.,Hackett,T.B.,Monnet,E.: :
Influence of open surgical correction on intermediate-term outcome in dogs with subvalvular aortic stenosis: 44 cases (1991-1998) Journal of the American Veterinary Medical Association 216:364-367, 2000.
Pubmed reference: 10668534 .
2000 Pyle,R.L.: :
Interpreting low-intensity cardiac murmurs in dogs predisposed to subaortic stenosis Journal of the American Animal Hospital Association 36:379-382, 2000.
Pubmed reference: 10997510 .
1998 Demoraes,A.N.,Dyson,D.H.,Ogrady,M.R.,Mcdonell,W.N.,Holmberg,D.L.: :
Plasma concentrations and cardiovascular influence of lidocaine infusions during isoflurane anesthesia in healthy dogs and dogs with subaortic stenosis Veterinary Surgery 27:486-497, 1998.
Pubmed reference: 9749521 .
1996 Monnet,E.,Orton,E.C.,Gaynor,J.S.,Boon,J.,Wagner,A.,Linn,K.,Eddleman,L.A.,Brevard,S.: :
Open resection for subvalvular aortic stenosis in dogs Journal of the American Veterinary Medical Association 209:1255-1261, 1996.
Pubmed reference: 8837645 .
1996 Nakayama,T.,Wakao,Y.,Ishikawa,R.,Takahashi,M.: :
Progression of subaortic stenosis detected by continuous wave doppler echocardiography in a dog Journal of Veterinary Internal Medicine 10:97-98, 1996.
Pubmed reference: 8683489 .
1996 Swift,S.: :
The problem of inherited diseases. 2. Subaortic stenosis in Boxers Journal of Small Animal Practice 37:351-352, 1996.
Pubmed reference: 8840258 .
1994 Kienle,R.D.,Thomas,W.P.,Pion,P.D.: :
The natural clinical history of canine congenital subaortic stenosis Journal of Veterinary Internal Medicine 8:423-431, 1994.
Pubmed reference: 7884729 .
1994 Lehmkuhl,L.B.,Bonagura,J.D.: :
Comparison of Transducer Placement Sites for Doppler Echocardiography in Dogs with Subaortic Stenosis American Journal of Veterinary Research 55:192-198, 1994.
Pubmed reference: 8172406 .
1993 Delellis,L.A.,Thomas,W.P.,Pion,P.D.: :
Balloon Dilation of Congenital Subaortic Stenosis in the Dog Journal of Veterinary Internal Medicine 7:153-162, 1993.
Pubmed reference: 8331609 .
1978 Muna,WF.,Ferrans,VJ.,Pierce,JE.,Roberts,WC.: :
Discrete subaortic stenosis in Newfoundland dogs: association of infective endocarditis. Am J Cardiol 41:746-54, 1978.
Pubmed reference: 565582 .
1976 Critchley,KL.: :
Sub-aortic stenosis in a Boxer dog. J Small Anim Pract 17:319-21, 1976.
Pubmed reference: 945430 .
1976 Pyle,RL.,Patterson,DF.,Chacko,S.: :
The genetics and pathology of discrete subaortic stenosis in the Newfoundland dog. Am Heart J 92:324-34, 1976.
Pubmed reference: 986114 .
1967 Flickinger,G.L.,Patterson,D.F.: :
Coronary lesions associated with congenital subaortic stenosis in the dog Journal of Pathology and Bacteriology 93:133-140, 1967.
Pubmed reference: 6067618 . DOI: 10.1002/path.1700930113 .
1963 Patterson,D.F.,Detweiler,D.K.: :
Predominance of German Shepherd and Boxer breeds among dogs with congenital subaortic stenosis American Heart Journal 65:249-430, 1963.
Pubmed reference: 13941902 .